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Binuclear palladacycles with ionisable and non-ionisable tethers as anticancer agents
Binuclear palladacycles with ionisable and non-ionisable tethers as anticancer agents
The search for novel anticancer agents to replace the current platinum-based treatments remains an ongoing process. Pallad...
In memoriam: F. Ann Walker (1940–2022)
In memoriam: F. Ann Walker (1940–2022)
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
A tribute to Frances Ann Walker
A tribute to Frances Ann Walker
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Design and anticancer behaviour of cationic/neutral half-sandwich iridium(III) imidazole-phenanthroline/phenanthrene complexes
Design and anticancer behaviour of cationic/neutral half-sandwich iridium(III) imidazole-phenanthroline/phenanthrene complexes
Today, cancer is one of the most important diseases endangering human life and health. Cisplatin, a clinically utilized me...
Oxygen affinities of DosT and DosS sensor kinases with implications for hypoxia adaptation in Mycobacterium tuberculosis
Oxygen affinities of DosT and DosS sensor kinases with implications for hypoxia adaptation in Mycobacterium tuberculosis
DosT and DosS are heme-based kinases involved in sensing and signaling O2 tension in the microenvironment of Mycobacterium...
Studies on synthesis and influence of sterically driven Ni(II)-terpyridine (NNN) complexes on BSA/DNA binding and anticancer activity
Studies on synthesis and influence of sterically driven Ni(II)-terpyridine (NNN) complexes on BSA/DNA binding and anticancer activity
2,2′:6′,2″-Terpyridines (Tpys) have been employed extensively in the development of metal-based catalysts, low-valent meta...
The impact of biomolecule interactions on the cytotoxic effects of rhenium(I) tricarbonyl complexes
The impact of biomolecule interactions on the cytotoxic effects of rhenium(I) tricarbonyl complexes
The search for new anticancer drugs is still ongoing, as well-established drugs containing platinum, such as cisplatin, ca...
Functional metalloenzymes based on myoglobin and neuroglobin that exploit covalent interactions
Functional metalloenzymes based on myoglobin and neuroglobin that exploit covalent interactions
Metalloproteins/metalloenzymes, such as heme or other metal-binding proteins and enzymes, perform a wide range of function...
Design, synthesis, and antitumor mechanism investigation of iridium(III) complexes conjugated with ibuprofen
Design, synthesis, and antitumor mechanism investigation of iridium(III) complexes conjugated with ibuprofen
Cancer has always been a major health challenge on a global scale [1,2]. The main treatment methods for cancer include sur...
Metallophthalocyanine as ideal antibiotics without light: Mechanisms and applications
Metallophthalocyanine as ideal antibiotics without light: Mechanisms and applications
AMR poses a severe threat to global health and causes numerous deaths worldwide. Antibiotic abuse worsens AMR situation. F...
The impact of chelating compounds on Cu2+, Fe2+/3+, and Zn2+ ions in Alzheimer's disease treatment
The impact of chelating compounds on Cu2+, Fe2+/3+, and Zn2+ ions in Alzheimer's disease treatment
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid – β extracellular pl...
Molecular insight into the structural and functional aspects of arene Ru(II) complexes bearing bulky thiourea ligands
Molecular insight into the structural and functional aspects of arene Ru(II) complexes bearing bulky thiourea ligands
Half-sandwich arene ruthenium complexes are exceptional in terms of developing metal therapeutic agents and as metal-based...
Ferrocene-modified half-sandwich iridium(III) and ruthenium(II) propionylhydrazone complexes and anticancer application
Ferrocene-modified half-sandwich iridium(III) and ruthenium(II) propionylhydrazone complexes and anticancer application
Cancer is a worldwide problem, and its morbidity and mortality are increasing year by year [1]. Now, the usage rate of pla...
Preparation and characterization of MnIIMnIII complexes with relevance to class Ib ribonucleotide reductases
Preparation and characterization of MnIIMnIII complexes with relevance to class Ib ribonucleotide reductases
The Mn2 complex [MnII2(TPDP)(O2CPh)2](BPh4) (1, TPDP = 1,3-bis(bis(pyridin-2-ylmethyl)amino)propan-2-ol, Ph =phenyl) was p...
Mitochondria-localizing triphenylphosphine-8-hydroxyquinoline Ru complexes induce ferroptosis and their antitumor evaluation
Mitochondria-localizing triphenylphosphine-8-hydroxyquinoline Ru complexes induce ferroptosis and their antitumor evaluation
Because of the toxic,side effects and the resistance of platinum drugs [[1], [2], [3], [4]], stimulating the research of n...
Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products
Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products
Members of the cytochrome P450 monooxygenase family play vital roles in the synthesis and degradation of many physiologica...
Small angle scattering reveals the orientation of cytochrome P450 19A1 in lipoprotein nanodiscs
Small angle scattering reveals the orientation of cytochrome P450 19A1 in lipoprotein nanodiscs
Volume 257, August 2024, 112579Author links open overlay panel, , , Highlights•Aromatase nanodiscs were characterized by s...
Silver(I) complexes with voriconazole as promising anti-Candida agents
Silver(I) complexes with voriconazole as promising anti-Candida agents
IR spectroscopyinfrared spectroscopyUV–Vis spectroscopyultraviolet-visible spectroscopyNMR spectroscopynuclear magnetic re...