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Localized gastroesophageal adenocarcinoma in the elderly: is age a factor associated with suboptimal treatment?
Localized gastroesophageal adenocarcinoma in the elderly: is age a factor associated with suboptimal treatment?
Introduction: Gastroesophageal adenocarcinoma is relatively common in elderly patients as the incidence increases with age...
Clinical T2N0 rectal cancer treated with neoadjuvant chemoradiotherapy plus local excision
Clinical T2N0 rectal cancer treated with neoadjuvant chemoradiotherapy plus local excision
Aim: Total mesorectal excision is the standard treatment for clinical T2 (cT2) rectal cancer; however, this procedure can ...
Real-World Experience of efficacy and safety of trabectedin in patients with soft tissue sarcoma: a bicentric retrospective analysis.
Real-World Experience of efficacy and safety of trabectedin in patients with soft tissue sarcoma: a bicentric retrospective analysis.
Introduction: Soft tissue sarcomas (STS) are a rare and heterogenous group of tumors, with poor prognostic, judging from t...
Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in locally advanced rectal cancer
Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic factors in locally advanced rectal cancer
INTRODUCTION The standard therapy for locally advanced rectal cancer is based on neoadjuvant chemoradiotherapy (nCRT) wit...
Expression of karyopherin alfa 2 and karyopherin beta 1 correlate with poor prognosis in gastric cancer
Expression of karyopherin alfa 2 and karyopherin beta 1 correlate with poor prognosis in gastric cancer
Introduction: Karyopherin alfa 2 (KPNA2) and karyopherin beta 1 (KPNB1), constitute nuclear transport protein complexes in...
Risk Factors of Postoperative Intra-Abdominal Infectious Complications After Robotic Gastrectomy for Gastric Cancer
Risk Factors of Postoperative Intra-Abdominal Infectious Complications After Robotic Gastrectomy for Gastric Cancer
Introduction: Robotic surgery is regarded as an evolved type of laparoscopic surgery. Few studies have undertaken detailed...
Genetic variants in histone modification regions predicts clinical outcomes of pemetrexed chemotherapy in lung adenocarcinoma
Genetic variants in histone modification regions predicts clinical outcomes of pemetrexed chemotherapy in lung adenocarcinoma
Objective This study was conducted to investigate the association between genetic variants in histone modification regions...
Clinical Implications of BRCA Mutations in Advanced Biliary Tract Cancer
Clinical Implications of BRCA Mutations in Advanced Biliary Tract Cancer
Introduction: Current standard chemotherapy for biliary tract cancer (BTC) has limited survival benefits, and the need for...
Adjuvant Capecitabine and Oxaliplatin for Elderly Patients with Colorectal Cancer
Adjuvant Capecitabine and Oxaliplatin for Elderly Patients with Colorectal Cancer
<b><i>Introduction:</i></b> Adjuvant chemotherapy improves the prognosis of patients with colorect...
CA19-9 in Combination with Methylated HOXA1 and SST Is Useful to Diagnose Stage I Pancreatic Cancer
CA19-9 in Combination with Methylated HOXA1 and SST Is Useful to Diagnose Stage I Pancreatic Cancer
Introduction: We previously developed a novel methylation assay, the combined restriction digital PCR (CORD) assay, consis...
Genomically stable gastric cancer characterized by hypomethylation in Wnt signal cascade
Genomically stable gastric cancer characterized by hypomethylation in Wnt signal cascade
Introduction Gastric cancer is divided into four subtypes by their molecular features linked with genetic alterations, e.g...
Multicenter retrospective analysis of original versus modified FOLFIRINOX in metastatic pancreatic cancer: Results of the NAPOLEON study
Multicenter retrospective analysis of original versus modified FOLFIRINOX in metastatic pancreatic cancer: Results of the NAPOLEON study
Introduction: Original FOLFIRINOX (oFFX) is more toxic than other regimens for patients with metastatic pancreatic cancer ...
The prognostic utilities of DNA mismatch repair status and KRAS and BRAF mutation in Korean colorectal cancer patients: The KASID multicenter study
The prognostic utilities of DNA mismatch repair status and KRAS and BRAF mutation in Korean colorectal cancer patients: The KASID multicenter study
Introduction KRAS, BRAF, and DNA mismatch repair (MMR) mutations aid clinical decision-making for colorectal cancer (CRC) ...
LENVATINIB MIGHT INDUCE ACTIVATION OF HOST IMMUNITY IN PATIENTS WITH HEPATOCELLULAR CARCINOMA
LENVATINIB MIGHT INDUCE ACTIVATION OF HOST IMMUNITY IN PATIENTS WITH HEPATOCELLULAR CARCINOMA
Introduction: Atezolizumab, an immune checkpoint inhibitor, plus bevacizumab, a monoclonal antibody that binds to vascular...
Oxidative stress as a biomarker for predicting the prognosis of patients with colorectal cancer
Oxidative stress as a biomarker for predicting the prognosis of patients with colorectal cancer
Introduction Excess oxidative stress is generated by inflammation and cancer, and it is involved in the development and me...
Biological difference between L858R and exon 19 deletion contributes to recurrence-free survival of resected non-small cell lung cancer
Biological difference between L858R and exon 19 deletion contributes to recurrence-free survival of resected non-small cell lung cancer
Introduction: The differences in biological characteristics among different genotypes of classical EGFR mutations have not...
Absolute lymphocyte count (ALC) as an independent prognostic factor in metastatic breast cancer: a retrospective study
Absolute lymphocyte count (ALC) as an independent prognostic factor in metastatic breast cancer: a retrospective study
Introduction Recently, absolute lymphocyte count (ALC) and neutrophil-to-lymphocyte ratio (NLR) have been reported to be ...
Eribulin treatment for patients with metastatic breast cancer: The United Kingdom experience - a multicenter retrospective study
Eribulin treatment for patients with metastatic breast cancer: The United Kingdom experience - a multicenter retrospective study
Purpose: This study examined real-world data from patients who received eribulin for metastatic breast cancer (MBC) collec...
Targeted therapies and utility of the Lung-molGPA in non-small-cell lung cancer patients with brain metastases
Targeted therapies and utility of the Lung-molGPA in non-small-cell lung cancer patients with brain metastases
Introduction: Therapeutic advances have increased the survival of non-small-cell lung cancer (NSCLC) patients as well as t...
Glucose conferred irinotecan chemoresistance through divergent actions of pyruvate and ATP in cell death and proliferation of colorectal cancer
Glucose conferred irinotecan chemoresistance through divergent actions of pyruvate and ATP in cell death and proliferation of colorectal cancer
Altered glucose metabolism is associated with chemoresistance in colorectal cancer (CRC). This study aimed to illustrate t...
The effect of vaccination against COVID-19 in cancer patients: 
final results of the COICA trial
The effect of vaccination against COVID-19 in cancer patients: final results of the COICA trial
Background The COICA study is an ambispective, observational trial that was conceived to assess the clinical course of SAR...
Role of sarcopenia in advanced malignant cutaneous melanoma treated with immunotherapy. A Meta Analysis
Role of sarcopenia in advanced malignant cutaneous melanoma treated with immunotherapy. A Meta Analysis
Objectives: The role of sarcopenia in malignant cutaneous melanoma is unclear. The aim of the present meta analysis was to...
High MT2A Expression Predicts Worse Prognosis in Patients with Urothelial Carcinoma
High MT2A Expression Predicts Worse Prognosis in Patients with Urothelial Carcinoma
Introduction: Dysregulation of metal ion homeostasis is associated with urothelial carcinogenesis. From a published urinar...
Symptom burden in glioblastoma - a prospective pilot study from diagnosis to first progression
Symptom burden in glioblastoma - a prospective pilot study from diagnosis to first progression
Introduction: The evaluation of symptom burden, performance status and neurological function is still challenging in gliob...