SCI时时刷

search
Effects of time of the day at sampling on CSF and plasma levels of Alzheimer’ disease biomarkers
Effects of time of the day at sampling on CSF and plasma levels of Alzheimer’ disease biomarkers
Studies suggest that cerebrospinal fluid (CSF) levels of amyloid-β (Aβ)42 and Aβ40 present a circadian rhyt...
Genetic and clinical landscape of Chinese frontotemporal dementia: dominance of TBK1 and OPTN mutations
Genetic and clinical landscape of Chinese frontotemporal dementia: dominance of TBK1 and OPTN mutations
Our study aims to evaluate the genetic and phenotypic spectrum of Frontotemporal dementia (FTD) gene variant carriers in C...
Brain age as a biomarker for pathological versus healthy ageing – a REMEMBER study
Brain age as a biomarker for pathological versus healthy ageing – a REMEMBER study
This study aimed to evaluate the potential clinical value of a new brain age prediction model as a single interpretable va...
Amyloid-PET imaging predicts functional decline in clinically normal individuals
Amyloid-PET imaging predicts functional decline in clinically normal individuals
There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associ...
Central autonomic network dysfunction and plasma Alzheimer’s disease biomarkers in older adults
Central autonomic network dysfunction and plasma Alzheimer’s disease biomarkers in older adults
Higher order regulation of autonomic function is maintained by the coordinated activity of specific cortical and subcortic...
Evaluating the inter-species transmission risk of amyloid beta peptide aggregates via ingestion
Evaluating the inter-species transmission risk of amyloid beta peptide aggregates via ingestion
Recent reports suggest that amyloid beta (Aβ) peptides can exhibit prion-like pathogenic properties. Transmission of ...
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly
Maximizing the efficiency to screen amyloid-positive individuals in asymptomatic and non-demented aged population using bl...
Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia
Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia
The gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnit...
Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype
Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype
Systemic inflammation and neuroinflammation affect the natural course of the sporadic form of Alzheimer’s disease (A...
Photobiomodulation in experimental models of Alzheimer’s disease: state-of-the-art and translational perspectives
Photobiomodulation in experimental models of Alzheimer’s disease: state-of-the-art and translational perspectives
Alzheimer’s disease (AD) poses a significant public health problem, affecting millions of people across the world. D...
Comparison of plasma and neuroimaging biomarkers to predict cognitive decline in non-demented memory clinic patients
Comparison of plasma and neuroimaging biomarkers to predict cognitive decline in non-demented memory clinic patients
Plasma biomarkers of Alzheimer’s disease (AD) pathology, neurodegeneration, and neuroinflammation are ideally suited...
The impact of incident stroke on cognitive trajectories in later life
The impact of incident stroke on cognitive trajectories in later life
Cognitive impairment is common after stroke, and a large proportion of stroke patients will develop dementia. However, the...
Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease
Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease
Alzheimer disease (AD) is a major health problem of aging, with tremendous burden on healthcare systems, patients, and fam...
Plasma biomarkers increase diagnostic confidence in patients with Alzheimer’s disease or frontotemporal lobar degeneration
Plasma biomarkers increase diagnostic confidence in patients with Alzheimer’s disease or frontotemporal lobar degeneration
The recent development of techniques to assess plasma biomarkers has changed the way the research community envisions the ...