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Characteristics of very late-onset schizophrenia-like psychosis as prodromal dementia with Lewy bodies: a cross-sectional study
Characteristics of very late-onset schizophrenia-like psychosis as prodromal dementia with Lewy bodies: a cross-sectional study
This study aimed to identify cases of potential prodromal DLB in very late-onset schizophrenia-like psychosis (VLOSLP), us...
Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults
Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults
Early detection of individuals at risk for Alzheimer’s disease (AD) is highly important. Amyloid accumulation is an ...
Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice
Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice
Alzheimer’s disease (AD) is characterized by a reorganization of brain activity determining network hyperexcitabilit...
Distinct sex-specific DNA methylation differences in Alzheimer’s disease
Distinct sex-specific DNA methylation differences in Alzheimer’s disease
Sex is increasingly recognized as a significant factor contributing to the biological and clinical heterogeneity in AD. Th...
A longitudinal study on quality of life along the spectrum of Alzheimer’s disease
A longitudinal study on quality of life along the spectrum of Alzheimer’s disease
Quality of life (QoL) is an important outcome from the perspective of patients and their caregivers, in both dementia and ...
Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease
Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease
The clinical features of Alzheimer’s disease (AD) vary substantially depending on whether the onset of cognitive def...
Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease
Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease
Low levels of plasma apolipoprotein E (apoE) and presence of the APOE ε4 allele are associated with an increased risk...
Increased plasma and brain immunoglobulin A in Alzheimer’s disease is lost in apolipoprotein E ε4 carriers
Increased plasma and brain immunoglobulin A in Alzheimer’s disease is lost in apolipoprotein E ε4 carriers
Alzheimer’s disease (AD) is foremost characterized by β-amyloid (Aβ)-extracellular plaques, tau-intraneuro...
Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data
Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data
Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major con...
Perspectives and challenges in patient stratification in Alzheimer’s disease
Perspectives and challenges in patient stratification in Alzheimer’s disease
Patient stratification is the division of a patient population into distinct subgroups based on the presence or absence of...
An explainable self-attention deep neural network for detecting mild cognitive impairment using multi-input digital drawing tasks
An explainable self-attention deep neural network for detecting mild cognitive impairment using multi-input digital drawing tasks
Mild cognitive impairment (MCI) is an early stage of cognitive decline which could develop into dementia. An early detecti...
Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer’s disease
Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer’s disease
Patients and caregivers express a desire for accurate prognostic information about time to institutionalization and mortal...
Discovery and validation of dominantly inherited Alzheimer’s disease mutations in populations from Latin America
Discovery and validation of dominantly inherited Alzheimer’s disease mutations in populations from Latin America
In fewer than 1% of patients, AD is caused by autosomal dominant mutations in either the presenilin 1 (PSEN1), presenilin ...
Investigating the power of eyes open resting state EEG for assisting in dementia diagnosis
Investigating the power of eyes open resting state EEG for assisting in dementia diagnosis
The differentiation of Lewy body dementia from other common dementia types clinically is difficult, with a considerable nu...
Early diagnosis of Alzheimer’s disease using machine learning: a multi-diagnostic, generalizable approach
Early diagnosis of Alzheimer’s disease using machine learning: a multi-diagnostic, generalizable approach
Early and accurate diagnosis of Alzheimer’s disease (AD) is essential for disease management and therapeutic choices...
Inflammatory plasma biomarkers in subjects with preclinical Alzheimer’s disease
Inflammatory plasma biomarkers in subjects with preclinical Alzheimer’s disease
This study investigated plasma biomarkers for neuroinflammation associated with Alzheimer’s disease (AD) in subjects...
Krüppel-like factor 5 accelerates the pathogenesis of Alzheimer’s disease via BACE1-mediated APP processing
Krüppel-like factor 5 accelerates the pathogenesis of Alzheimer’s disease via BACE1-mediated APP processing
The deposition of β-amyloid (Aβ) in the brain plays a major role in the pathogenesis of Alzheimer’s diseas...
Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects—a MissionAD tau sub-study
Evaluation of tau deposition using 18F-PI-2620 PET in MCI and early AD subjects—a MissionAD tau sub-study
The ability of 18F-PI-2620 PET to measure the spatial distribution of tau pathology in Alzheimer’s disease (AD) has ...
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways
The S209F variant of Abelson Interactor Protein 3 (ABI3) increases risk for Alzheimer’s disease (AD), but little is ...
A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing
A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing
Neuronal hyperexcitability and inhibitory interneuron dysfunction are frequently observed in preclinical animal models of ...
Decreased visual acuity is related to thinner cortex in cognitively normal adults: cross-sectional, single-center cohort study
Decreased visual acuity is related to thinner cortex in cognitively normal adults: cross-sectional, single-center cohort study
Decreased visual acuity (VA) is reported to be a risk factor for dementia. However, the association between VA and cortica...
Grey matter changes on brain MRI in subjective cognitive decline: a systematic review
Grey matter changes on brain MRI in subjective cognitive decline: a systematic review
People with subjective cognitive decline (SCD) report cognitive deterioration. However, their performance in neuropsycholo...
Prodromal characteristics of dementia with Lewy bodies: baseline results of the MEMENTO memory clinics nationwide cohort
Prodromal characteristics of dementia with Lewy bodies: baseline results of the MEMENTO memory clinics nationwide cohort
Isolated subjective cognitive impairment (SCI) and mild cognitive impairment (MCI) are the prodromal phases of dementia wi...
P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles
P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles
We previously identified four Alzheimer’s disease (AD) subgroups with increasingly higher cerebrospinal fluid (CSF) ...