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Accuracy of plasma Aβ40, Aβ42, and p-tau181 to detect CSF Alzheimer’s pathological changes in cognitively unimpaired subjects using the Lumipulse automated platform
Accuracy of plasma Aβ40, Aβ42, and p-tau181 to detect CSF Alzheimer’s pathological changes in cognitively unimpaired subjects using the Lumipulse automated platform
The arrival of new disease-modifying treatments for Alzheimer’s disease (AD) requires the identification of subjects...
Stress, depression, and risk of dementia – a cohort study in the total population between 18 and 65 years old in Region Stockholm
Stress, depression, and risk of dementia – a cohort study in the total population between 18 and 65 years old in Region Stockholm
Chronic stress and depression are potential risk factors for mild cognitive impairment and dementia, including Alzheimer d...
Retraction Note: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis
Retraction Note: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13195-021-0076...
Correction: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer’s disease and mild cognitive impairment
Correction: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer’s disease and mild cognitive impairment
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease
Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease
Neuron-derived extracellular vesicles (NDEVs) in blood may be used to derive biomarkers for the effects of exercise in Alz...
Cost-effectiveness of physical activity interventions for prevention and management of cognitive decline and dementia—a systematic review
Cost-effectiveness of physical activity interventions for prevention and management of cognitive decline and dementia—a systematic review
Although increasing physical activity (PA) has been suggested to prevent and manage cognitive decline and dementia, its ec...
Effects of computerized cognitive training on structure‒function coupling and topology of multiple brain networks in people with mild cognitive impairment: a randomized controlled trial
Effects of computerized cognitive training on structure‒function coupling and topology of multiple brain networks in people with mild cognitive impairment: a randomized controlled trial
People with mild cognitive impairment (MCI) experience a loss of cognitive functions, whose mechanism is characterized by ...
Home-based transcranial alternating current stimulation (tACS) in Alzheimer’s disease: rationale and study design
Home-based transcranial alternating current stimulation (tACS) in Alzheimer’s disease: rationale and study design
Gamma (γ) brain oscillations are dysregulated in Alzheimer’s disease (AD) and can be modulated using transcrani...
The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury
The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury
Preclinical studies highlight the importance of endogenous cannabinoids (endocannabinoids; eCBs) in neurodegeneration. Yet...
Is later-life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post-mortem human brain tissue?
Is later-life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post-mortem human brain tissue?
Depression and dementia are both common diseases. Although new cases of depression are more common in younger adults, ther...
Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population
Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population
The relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate...
REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals
REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals
Rapid-eye movement (REM) sleep highly depends on the activity of cholinergic basal forebrain (BF) neurons and is reduced i...
Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias
Diagnostic and prognostic value of cerebrospinal fluid SNAP-25 and neurogranin in Creutzfeldt-Jakob disease in a clinical setting cohort of rapidly progressive dementias
The levels of synaptic markers synaptosomal-associated protein 25 (SNAP-25) and neurogranin (Ng) have been shown to increa...
Performance of plasma Aβ42/40, measured using a fully automated immunoassay, across a broad patient population in identifying amyloid status
Performance of plasma Aβ42/40, measured using a fully automated immunoassay, across a broad patient population in identifying amyloid status
Plasma biomarkers have emerged as promising screening tools for Alzheimer’s disease (AD) because of their potential ...
A plasma protein signature associated with cognitive function in men without severe cognitive impairment
A plasma protein signature associated with cognitive function in men without severe cognitive impairment
A minimally invasive blood-based assessment of cognitive function could be a promising screening strategy to identify high...
A polygenic risk score for Alzheimer’s disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S.
A polygenic risk score for Alzheimer’s disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S.
Polygenic Risk Scores (PRSs) are summaries of genetic risk alleles for an outcome. We used summary statistics fro...
Automating Rey Complex Figure Test scoring using a deep learning-based approach: a potential large-scale screening tool for cognitive decline
Automating Rey Complex Figure Test scoring using a deep learning-based approach: a potential large-scale screening tool for cognitive decline
The Rey Complex Figure Test (RCFT) has been widely used to evaluate the neurocognitive functions in various clinical group...
Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study
Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxyglucose-positron emission tomography study
Despite the high sensitivity of cerebrospinal fluid (CSF) amyloid beta (Aβ)42 to detect amyloid pathology, the Aβ...
Prediction of post-stroke cognitive impairment after acute ischemic stroke using machine learning
Prediction of post-stroke cognitive impairment after acute ischemic stroke using machine learning
Post-stroke cognitive impairment (PSCI) occurs in up to 50% of patients with acute ischemic stroke (AIS). Thus, the predic...
High-intensity walking in midlife is associated with improved memory in physically capable older adults
High-intensity walking in midlife is associated with improved memory in physically capable older adults
Little is known about the associations of midlife- and late life-initiated walking with Alzheimer’s disease (AD)-rel...
Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes
Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes
Studies in animal models of Alzheimer’s disease (AD) have provided valuable insights into the molecular and cellular...
Circulating insulin-like growth factor-1 and brain health: Evidence from 369,711 participants in the UK Biobank
Circulating insulin-like growth factor-1 and brain health: Evidence from 369,711 participants in the UK Biobank
The effects of insulin-like growth factor-1 (IGF-1) deficiency on cognitive decline have been consistently reported in ani...
A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patients
A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patients
Mounting evidence suggests the involvement of viruses in the development and treatment of Alzheimer’s disease (AD). ...
Correction: Repurposed agents in the Alzheimer’s disease drug development pipeline
Correction: Repurposed agents in the Alzheimer’s disease drug development pipeline
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank
Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank
Associations between kidney function and dementia risk are inconclusive. Chronic kidney disease (CKD) severity is determin...
Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to AppNL−G−F knock-in Alzheimer mice
Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to AppNL−G−F knock-in Alzheimer mice
Alzheimer’s disease (AD) is an age-related disease characterized by altered cognition, neuroinflammation, and neurod...
Risk of dementia in primary aldosteronism compared with essential hypertension: a nationwide cohort study
Risk of dementia in primary aldosteronism compared with essential hypertension: a nationwide cohort study
Although hypertension is a critical risk factor for dementia, the association between primary aldosteronism (PA) and demen...
Network analysis of neuropsychiatric symptoms in Alzheimer’s disease
Network analysis of neuropsychiatric symptoms in Alzheimer’s disease
Neuropsychiatric symptoms due to Alzheimer’s disease (AD) and mild cognitive impairment (MCI) can decrease quality o...
Cerebrospinal fluid lipidomic fingerprint of obstructive sleep apnoea in Alzheimer’s disease
Cerebrospinal fluid lipidomic fingerprint of obstructive sleep apnoea in Alzheimer’s disease
Obstructive sleep apnoea (OSA) has a high prevalence in patients with Alzheimer’s disease (AD). Both conditions have...
Impacts of baseline biomarkers on cognitive trajectories in subjective cognitive decline: the CoSCo prospective cohort study
Impacts of baseline biomarkers on cognitive trajectories in subjective cognitive decline: the CoSCo prospective cohort study
Subjective cognitive decline (SCD) is a risk factor for Alzheimer’s disease (AD); however, the rates of cognitive de...
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