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MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway
PurposeTo investigate the efficacy and mechanisms of human umbilical cord-derived MSC-derived extracellular vesicles (hucM...
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells
Available online 24 March 2023Author links open overlay panel, , Section snippetsFundingThis work was supported by institu...
Allergic contact dermatitis of the eyelids: An interdisciplinary review
Allergic contact dermatitis (ACD) is an immune-mediated skin reaction that causes an erythematous and pruritic rash upon e...
Genipin increases extracellular matrix synthesis preventing corneal perforation
The stroma comprises 90% of the corneal tissue and consists of water, and extracellular matrix─ mainly various collagens a...
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas
The naïve cornea is an avascular tissue but is well-reported to harbor antigen-presenting cells (APCs) [1]. These APCs are...
Contact lens-induced corneal parainflammation involving Ly6G+ cell infiltration requires IL-17A and γδ T cells
Contact lens wear is a common form of vision correction with more than 140 million wearers worldwide. Contact lens-associa...
Experimental design considerations for studies of human tear proteins
Human tears are critical in the maintenance of ocular surface homeostasis and exhibit differential composition in states o...
Trustworthy Research Presentations
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Readership awareness series – Paper 3: Paper mills
Available online 3 February 2023Author links open overlay panel, Section snippetsModus operandiWhile the modus operandi is...
Managing chronic inflammation in ocular sequelae of Stevens Johnson Syndrome to restore vision
Available online 28 January 2023Author links open overlay panelSection snippetsFundingNo funding received.Financial disclo...
Detecting dry eye from ocular surface videos based on deep learning
Dry eye (DE) is a very common multifactorial disorder characterized by loss of tear film homeostasis that may result in di...
Cicatricial entropion in eyes with lid margin mucous membrane grafting
Available online 24 January 2023Author links open overlay panelSection snippetsTextLid margin mucous membrane grafting (MM...
The work-related burden of dry eye
Available online 21 January 2023Author links open overlay panelAbstractPurposeTo investigate the relationship between dry ...
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease
Available online 20 January 2023Author links open overlay panelSection snippetsFundingThis research did not receive any sp...
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study
Herpes Simplex Virus (HSV) keratitis is the most common frequent infectious cause of corneal blindness in industrialized c...
Can Janus kinase inhibition improve ocular graft versus host disease?
Available online 10 January 2023Author links open overlay panelSection snippetsFinancial supportCigarette Restitution Fund...
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature
Mycoplasma pneumoniae (M. pneumoniae) is a significant cause of pulmonary and extrapulmonary infections in children and ad...
The relationship between sedentary behavior and dry eye disease
Dry eye disease (DED) is a common multifactorial disease of the tears and ocular surface characterized by tear film instab...
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia
Ocular surface squamous neoplasia (OSSN) is an umbrella term for a spectrum of disease on the cornea and conjunctiva rangi...
A systematic review on the effects of ROCK inhibitors on proliferation and/or differentiation in human somatic stem cells: A hypothesis that ROCK inhibitors support corneal endothelial healing via acting on the limbal stem cell niche
In recent years, there has been growing interest regarding the promotion of corneal endothelial (CE) healing by rho kinase...
A phase 2a, double-masked, randomized, vehicle-controlled trial of VVN001 in subjects with dry eye disease
“Dry eye disease (DED) is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tea...
Face mask use and effects on the ocular surface health: A comprehensive review
In the COVID-19 period, face masks took a front role in decreasing viral transmission and established as one of the main p...
Management of scleral melt
Available online 19 December 2022Author links open overlay panelAbstractScleral melting, while rare, can lead to significa...
Apolipoprotein A1 is associated with meibomian gland dropout
Available online 16 December 2022Author links open overlay panelSection snippetsFundingThis study was supported by the Nat...
Modulation of ocular surface desiccation in a murine model by histatin-5 application
Dry eye disease (DED) is a complex and multifactorial disorder of the ocular surface with an estimated global prevalence o...
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic
Available online 5 December 2022Author links open overlay panelE.GreenanE.VandenbergheE.ConneallyC.C.MurphyPersonEnvelopeJ...
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study
Ocular surface squamous neoplasia (OSSN) is the most common malignancy of the ocular surface and comprises a spectrum of d...
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures
Ocular microsporidiosis comprises two entirely different spectra of disease as keratoconjunctivitis and stromal keratitis....
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining
M.S: None, N·S.A: None, R.B: None, H.M.M: None, S.G: None, A.T: None, P·S.M: None, M.J.A: None, S·W·C: None, A.L.S: GlaxoS...
Psychological distress in patients with ocular graft-versus-host disease after hematopoietic stem cell transplantation
Available online 22 November 2022Author links open overlay panelSection snippetsFunding/supportThis work was supported by ...
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