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CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis
CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis
AbstractBackground and Objectives In multiple sclerosis (MS), peripheral immune cells use various cell trafficking molecul...
Microglia as Central Protagonists in the Chronic Stress Response
Microglia as Central Protagonists in the Chronic Stress Response
AbstractChronic stress is a major risk factor for developing psychiatric conditions. In addition to elevating the levels o...
Toward Precision Phenotyping of Multiple Sclerosis
Toward Precision Phenotyping of Multiple Sclerosis
AbstractThe classification of multiple sclerosis (MS) has been established by Lublin in 1996 and revised in 2013. The revi...
IgG4 Valency Modulates the Pathogenicity of Anti-Neurofascin-155 IgG4 in Autoimmune Nodopathy
IgG4 Valency Modulates the Pathogenicity of Anti-Neurofascin-155 IgG4 in Autoimmune Nodopathy
AbstractBackground and Objectives IgG4 autoantibodies to neurofascin-155 (Nfasc155) are associated with a subgroup of pati...
Cerebellar Ataxia With Anti-DNER Antibodies: Outcomes and Immunologic Features
Cerebellar Ataxia With Anti-DNER Antibodies: Outcomes and Immunologic Features
AbstractBackground and Objectives There is no report on the long-term outcomes of ataxia with antibodies against Delta and...
Increased Intrathecal Activity of Follicular Helper T Cells in Patients With Relapsing-Remitting Multiple Sclerosis
Increased Intrathecal Activity of Follicular Helper T Cells in Patients With Relapsing-Remitting Multiple Sclerosis
AbstractBackground and Objectives Follicular helper T (Tfh) cells play a critical role in protective immunity helping B ce...
AMPA Receptor Encephalitis in a Patient With Metastatic Breast Cancer Receiving Palbociclib: A Case Report
AMPA Receptor Encephalitis in a Patient With Metastatic Breast Cancer Receiving Palbociclib: A Case Report
AbstractObjective To report a case of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis (AMPARE) ...
Younger Age at Onset Is Associated With Worse Long-term Behavioral Outcomes in Anti-NMDA Receptor Encephalitis
Younger Age at Onset Is Associated With Worse Long-term Behavioral Outcomes in Anti-NMDA Receptor Encephalitis
AbstractBackground and Objectives Anti-NMDA receptor encephalitis (anti-NMDARE) is one of the most common causes of enceph...
Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies
Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies
AbstractBackground and Objectives Paraneoplastic cerebellar degeneration (PCD) is characterized by a widespread loss of Pu...
Long-term Effectiveness of IVIg Maintenance Therapy in 36 Patients With GAD Antibody-Positive Stiff-Person Syndrome
Long-term Effectiveness of IVIg Maintenance Therapy in 36 Patients With GAD Antibody-Positive Stiff-Person Syndrome
AbstractBackground and Objectives IVIg has been the preferred immunotherapy in stiff-person syndrome (SPS) based on a 3-mo...
Immune Response and Safety of SARS-CoV-2 mRNA-1273 Vaccine in Patients With Myasthenia Gravis
Immune Response and Safety of SARS-CoV-2 mRNA-1273 Vaccine in Patients With Myasthenia Gravis
AbstractBackground and Objectives Evidence regarding the safety and efficacy of messenger RNA (mRNA) vaccines in patients ...
Disease-Modifying Drugs for Multiple Sclerosis and Association With Survival
Disease-Modifying Drugs for Multiple Sclerosis and Association With Survival
AbstractBackground and Objectives We examined the association between the disease-modifying drugs (DMDs) for multiple scle...
CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells
CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells
AbstractBackground and Objectives Experimental studies indicate shared molecular pathomechanisms in cerebral hypoxia-ische...
Ofatumumab Modulates Inflammatory T Cell Responses and Migratory Potential in Patients With Multiple Sclerosis
Ofatumumab Modulates Inflammatory T Cell Responses and Migratory Potential in Patients With Multiple Sclerosis
AbstractBackground and Objectives The anti-CD20 antibody ofatumumab is an efficacious therapy for multiple sclerosis (MS) ...
Retinal Hyperreflecting Foci Associate With Cortical Pathology in Multiple Sclerosis
Retinal Hyperreflecting Foci Associate With Cortical Pathology in Multiple Sclerosis
AbstractBackground and Objectives Microglia, the resident immune cell of the brain and retina, is widespread activated in ...
The BCL2 Inhibitor Venetoclax Plus Rituximab Is Active in MYD88 Wild-Type Polyneuropathy With Anti-MAG Antibodies
The BCL2 Inhibitor Venetoclax Plus Rituximab Is Active in MYD88 Wild-Type Polyneuropathy With Anti-MAG Antibodies
AbstractObjectives Ibrutinib is active in anti–myelin-associated glycoprotein (MAG) polyneuropathy with MYD88L265P mutatio...
{beta}IV-Spectrin Autoantibodies in 2 Individuals With Neuropathy of Possible Paraneoplastic Origin: A Case Series
{beta}IV-Spectrin Autoantibodies in 2 Individuals With Neuropathy of Possible Paraneoplastic Origin: A Case Series
AbstractObjective To identify the autoantigen in 2 individuals with possible seronegative paraneoplastic neuropathy.Method...