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Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Heart failure (HF) remains a leading cause of mortality, responsible for 13% of all deaths worldwide. The prognosis for pa...
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
The skin and cardiovascular systems are connected in unique and meaningful ways, and many diseases conventionally consider...
Improving English proficiency for scientific communication by non-fluent speakers
English has long been the dominant language in scientific communication. Although having a universal language for scientif...
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Debate exists regarding the best terminology for common presentations of heart diseases caused by epicardial and/or microv...
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
After myocardial infarction, monocytes are actively recruited to the brain to augment sleep power and abundance, which in ...
Our revered and mysterious heart
Our revered and mysterious heart
A review of Robin Choudhury’s book The Beating Heart: The Art & Science of Our Most Vital Organ, which explo...
Nanomedicine-based strategies for the treatment of vein graft disease
Nanomedicine-based strategies for the treatment of vein graft disease
Autologous saphenous veins are the most frequently used conduits for coronary and peripheral artery bypass grafting. Howev...
Environmental sustainability in cardiovascular practice: current challenges and future directions
Environmental sustainability in cardiovascular practice: current challenges and future directions
Cardiovascular disease is the leading cause of morbidity and mortality worldwide, with a substantial amount of health-care...
OpenEP and EP Workbench for electrophysiology data analysis
OpenEP and EP Workbench for electrophysiology data analysis
In this Tools of the Trade article, Bodagh and Williams highlight the utility of OpenEP, an open-source platform that offe...
Translation of pathophysiological mechanisms of atrial fibrosis into new diagnostic and therapeutic approaches
Translation of pathophysiological mechanisms of atrial fibrosis into new diagnostic and therapeutic approaches
Atrial fibrosis is one of the main manifestations of atrial cardiomyopathy, an array of electrical, mechanical and structu...
Lower your cholesterol early, and stick with it!
Lower your cholesterol early, and stick with it!
Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions. Two new studies document that, ...
Pathophysiology of dilated cardiomyopathy: from mechanisms to precision medicine
Pathophysiology of dilated cardiomyopathy: from mechanisms to precision medicine
Dilated cardiomyopathy (DCM) is a complex disease with multiple causes and various pathogenic mechanisms. Despite improvem...
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures
Over the past 50 years, the number and invasiveness of percutaneous cardiovascular procedures globally have increased subs...
β-blockers after MI: does ABYSS confirm REDUCEd use after all?
In contrast to the ABYSS investigators’ interpretation of the primary results of their trial, we believe that β...
Cryo-X-ray phase contrast imaging for 3D structural and molecular analysis of frozen biopsy samples
Cryo-X-ray phase contrast imaging for 3D structural and molecular analysis of frozen biopsy samples
In this Tools of the Trade article, Li and Bonnin describe the use of cryo-X-ray phase contrast imaging to assess frozen m...
Turning back time: the promise of cardiac regeneration
Elsa Lawrence and Catherine Wilson discuss the study that reported the existence of a transient regenerative window in mam...
Minority stress, discrimination and cardiovascular health
John C. Lin and colleagues explore the history of racial disparities in cardiovascular outcomes and discuss the landmark f...
20 years of Nature Reviews Cardiology
20 years of Nature Reviews Cardiology
The 20th anniversary of Nature Reviews Cardiology comes at a time of exciting innovation for cardiovascular research and c...
The burden of atrial fibrillation in the Asia–Pacific region
The burden of atrial fibrillation in the Asia–Pacific region
The burden of atrial fibrillation (AF) is increasing worldwide; however, most existing data on AF epidemiology are from We...
Soil and water pollution and cardiovascular disease
Soil and water pollution and cardiovascular disease
Healthy, uncontaminated soils and clean water support all life on Earth and are essential for human health. Chemical pollu...
The molecular landscape of vascular cells in the human brain
The molecular landscape of vascular cells in the human brain
A study using advanced single-cell technologies has broadened our understanding of the diversity and complexity of brain e...
Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis
Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis
Lysosomes have a central role in the disposal of extracellular and intracellular cargo and also function as metabolic sens...
Benefit of vutrisiran in transthyretin amyloidosis with cardiomyopathy
Data from the HELIOS-B trial show that RNA interference with vutrisiran reduces the risk of death and recurrent cardiovasc...
TEER is non-inferior to surgery in patients with secondary mitral regurgitation
TEER is non-inferior to surgery in patients with secondary mitral regurgitation
In patients with heart failure and secondary mitral valve regurgitation, transcatheter edge-to-edge repair is non-inferior...
Combining TAVI with PCI in patients with aortic stenosis and CAD
In the NOTION-3 trial, percutaneous coronary intervention reduced the occurrence of major adverse cardiac events compared ...
Finerenone improves outcomes in HFmrEF and HFpEF
Finerenone improves outcomes in HFmrEF and HFpEF
The non-steroidal mineralocorticoid receptor antagonist finerenone reduces the risk of adverse outcomes in patients with h...
Combined measure of inflammation, cholesterol and lipoprotein(a) predicts 30-year cardiovascular risk in women
A single combined measurement of high-sensitivity C-reactive protein, LDL-cholesterol and lipoprotein(a) levels in plasma ...
Interferon response at the border zone of the infarcted heart
Interferon response at the border zone of the infarcted heart
Cardiomyocytes can activate the type I interferon response in the infarct border zone after myocardial infarction, indicat...
Clonal haematopoiesis: an emerging causal risk factor for atherosclerotic CVD
New research suggests that the presence of clonal haematopoiesis is unidirectionally associated with the development of at...
The gut microbiota in thrombosis
The gut microbiota in thrombosis
The gut microbiota has emerged as an environmental risk factor that affects thrombotic phenotypes in several cardiovascula...
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