SCI时时刷

search
+
Combined measure of inflammation, cholesterol and lipoprotein(a) predicts 30-year cardiovascular risk in women
A single combined measurement of high-sensitivity C-reactive protein, LDL-cholesterol and lipoprotein(a) levels in plasma ...
Interferon response at the border zone of the infarcted heart
Interferon response at the border zone of the infarcted heart
Cardiomyocytes can activate the type I interferon response in the infarct border zone after myocardial infarction, indicat...
Clonal haematopoiesis: an emerging causal risk factor for atherosclerotic CVD
New research suggests that the presence of clonal haematopoiesis is unidirectionally associated with the development of at...
The gut microbiota in thrombosis
The gut microbiota in thrombosis
The gut microbiota has emerged as an environmental risk factor that affects thrombotic phenotypes in several cardiovascula...
Reproductive options and genetic testing for patients with an inherited cardiac disease
Reproductive options and genetic testing for patients with an inherited cardiac disease
In the past decade, genetic testing for cardiac disease has become part of routine clinical care. A genetic diagnosis prov...
Differential roles of eosinophils in cardiovascular disease
Differential roles of eosinophils in cardiovascular disease
Eosinophils are essential innate immune cells in allergic responses. Accumulating evidence indicates that eosinophils also...
Atheroimmunology: keeping the immune system in atherosclerosis in check
Atheroimmunology: keeping the immune system in atherosclerosis in check
The immune response is not unlike a game of chess, with white and black pieces playing opposing roles and orchestrating an...
Pathophysiological insights into HFpEF from studies of human cardiac tissue
Pathophysiological insights into HFpEF from studies of human cardiac tissue
Heart failure with preserved ejection fraction (HFpEF) is a major, worldwide health-care problem. Few therapies for HFpEF ...
Stroke triggers an innate immune memory that drives cardiac dysfunction
Stroke triggers an innate immune memory that drives cardiac dysfunction
Acute ischaemic stroke induces persistent innate immune memory through epigenetic changes in myeloid progenitors in the bo...
Mechanisms and treatment of pulmonary arterial hypertension
Mechanisms and treatment of pulmonary arterial hypertension
Substantial progress has been made in the management of pulmonary arterial hypertension (PAH) in the past 25 years, but th...
Reactive oxygen species in hypertension
Reactive oxygen species in hypertension
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors a...
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
In Latin America and the Caribbean (LAC), sociodemographic context, socioeconomic disparities and the high level of urbani...
Potential new therapeutic target for HFpEF
Potential new therapeutic target for HFpEF
A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model...
Cardiac sarcomere turnover by unidirectional replacement of proteins
Cardiac sarcomere turnover by unidirectional replacement of proteins
A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by n...
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
The accessibility of the retina with the use of non-invasive and relatively low-cost ophthalmic imaging techniques and ana...
The LDL cumulative exposure hypothesis: evidence and practical applications
The LDL cumulative exposure hypothesis: evidence and practical applications
The trapping of LDL and other apolipoprotein B-containing lipoproteins within the artery wall causes atherosclerosis. As m...
Consequences of ionizing radiation exposure to the cardiovascular system
Consequences of ionizing radiation exposure to the cardiovascular system
Ionizing radiation is widely used in various industrial and medical applications, resulting in increased exposure for cert...
Functional control of myosin motors in the cardiac cycle
Functional control of myosin motors in the cardiac cycle
Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. ...
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
For more than 60 years, humans have travelled into space. Until now, the majority of astronauts have been professional, go...
Cardiac involvement in Chagas disease and African trypanosomiasis
Cardiac involvement in Chagas disease and African trypanosomiasis
Trypanosomiases are diseases caused by various species of protozoan parasite in the genus Trypanosoma, each presenting wit...
Dietary patterns to promote cardiometabolic health
Dietary patterns to promote cardiometabolic health
Multiple professional societies recommend the Mediterranean and/or Dietary Approaches to Stop Hypertension dietary pattern...
Transcatheter treatment of pure aortic regurgitation
Transcatheter treatment of pure aortic regurgitation
Preliminary experience with the use of transcatheter aortic valve implantation (TAVI) to treat non-calcific aortic regurgi...
Autoimmune diseases and atherosclerotic cardiovascular disease
Autoimmune diseases and atherosclerotic cardiovascular disease
Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic cardiovascular disease and its cl...
Pulsed-field ablation: a revolution in atrial fibrillation therapy
The advent of pulsed-field ablation — a series of ultra-rapid, high-energy pulses that result in non-thermal cell de...
Global epidemiology of heart failure
Global epidemiology of heart failure
Heart failure (HF) is a heterogeneous clinical syndrome marked by substantial morbidity and mortality. The natural history...
Suture-to-scan: ultrasonography-guided induction of heart injury
Suture-to-scan: ultrasonography-guided induction of heart injury
In this Tools of the Trade article, Berkeley and Thomson describe the use of a minimally invasive strategy to standardize ...
Proximity-based labelling for proteomic mapping
Proximity-based labelling for proteomic mapping
In this Tools of the Trade article, Jablonska describes the use of proximity-based labelling for the proteomic profiling o...
Epigenetic changes in HSCs contribute to HF and comorbidities
Epigenetic changes in HSCs contribute to HF and comorbidities
Findings from a new study published in Science Immunology suggest that epigenetic changes in haematopoietic stem cells pro...
RNA interference lowers triglyceride levels
Data from the phase IIb MUIR and ARCHES-2 trials show that RNA interference approaches that target either apolipoprotein C...
Characterization of the F8 gene: a silver lining in a dark cloud
Haemophilia A is caused by variants in the gene that encodes coagulation factor VIII (FVIII). Sequencing of this gene in t...
阅读更多
format_indent_increase