SCI时时刷

search
+
No benefit of β-blockers after myocardial infarction with preserved ejection fraction
In the REDUCE-AMI trial, the use of β-blockers in patients with acute myocardial infarction (MI) who have undergone e...
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy
According to data from the IMPROVE-HCM trial, ninerafaxstat is well tolerated by patients with symptomatic non-obstructive...
Heart pump increases survival in STEMI-related cardiogenic shock
Heart pump increases survival in STEMI-related cardiogenic shock
Data from the DanGer Shock trial demonstrate that implantation of a microaxial flow pump in patients with ST-segment eleva...
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia
Three randomized clinical trials presented at ACC.24 demonstrate that olezarsen and plozasiran, RNA-based therapies that t...
Strategies for the delivery of sex-based equity in cardiovascular clinical trials
The under-representation of women in cardiovascular clinical trials persists across participant, clinician and research ro...
Self-expanding valves more beneficial than balloon-expandable valves in patients with a small aortic annulus
Self-expanding valves more beneficial than balloon-expandable valves in patients with a small aortic annulus
In patients with symptomatic aortic stenosis and a small aortic annulus, a self-expanding valve has similar rates of clini...
Gut bacteria can break down cholesterol
Gut bacteria can break down cholesterol
A new study identifies a group of gut bacteria that can metabolize cholesterol and are associated with lower plasma choles...
Canonical and non-canonical roles of complement in atherosclerosis
Canonical and non-canonical roles of complement in atherosclerosis
Cardiovascular diseases are the leading cause of death globally, and atherosclerosis is the major contributor to the devel...
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and mortality globally, and these condit...
Uncovering atherosclerotic cardiovascular disease by PET imaging
Uncovering atherosclerotic cardiovascular disease by PET imaging
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically, there is a need to ident...
Small extracellular vesicles from the infarcted heart can promote tumour growth
Small extracellular vesicles from the infarcted heart can promote tumour growth
After myocardial infarction, the heart secretes small extracellular vesicles with pro-neoplastic properties that can accel...
Interventional thrombus modification in STEMI
Interventional thrombus modification in STEMI
In ST-segment elevation myocardial infarction, the role of interventional modification of thrombi in the coronary arteries...
Alain Cribier (1945–2024)
Alain Cribier (1945–2024)
Gilard and Wijns reflect on the life of Alain Cribier, who revolutionized the management of patients with valvular disease.
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
Author Correction: 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease
Division of Adult Cardiology, Uganda Heart Institute, Kampala, UgandaJoselyn Rwebembera & Emmy OkelloGlobal and Tropic...
Contemporary pharmacological treatment and management of heart failure
Contemporary pharmacological treatment and management of heart failure
The prevention and treatment strategies for heart failure (HF) have evolved in the past two decades. The stages of HF have...
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Balancing the safety and efficacy of antithrombotic agents in patients with gastrointestinal disorders is challenging beca...
Presence of microplastics in carotid plaques linked to cardiovascular events
In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associate...
Long-read sequencing provides insights into genetic influence
Long-read sequencing provides insights into genetic influence
In this Tools of the Trade article, Trivett discusses the potential of long-read sequencing in generating high-quality ref...
Protein glycosylation in cardiovascular health and disease
Protein glycosylation in cardiovascular health and disease
Protein glycosylation, which involves the attachment of carbohydrates to proteins, is one of the most abundant protein co-...
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has...
Novel cardiovascular therapeutics and the risk of financial toxicity
Novel cardiovascular therapeutics have the potential to improve health outcomes, but financial toxicity from high out-of-p...
Imaging cAMP nanodomains in human iPSC-derived cardiomyocytes
Imaging cAMP nanodomains in human iPSC-derived cardiomyocytes
In this Tools of the Trade article, Charrière describes the FluoStep FRET-based biosensor used for high-resolution im...
Tackling inflammation in atherosclerosis
Shoaran and Maffia recount how our understanding of the role of inflammation in atherosclerosis has evolved and highlight ...
Modelling pre-eclampsia and its cardiovascular effects
Modelling pre-eclampsia and its cardiovascular effects
In this Tools of the Trade article, Olivera describes a rat model of pre-elampsia that has been instrumental for investiga...
An epigenome editing approach induces durable silencing of Pcsk9
A new approach to modify the epigenome can lead to durable silencing of Pcsk9 in mice, thereby reducing plasma LDL-cholest...
Cardiac memory: a phenomenon with important clinical implications
Rebecca Gilchrist discusses the study that demonstrated the long-term modulation of ventricular repolarization by the sequ...
Sex-related similarities and differences in responses to heart failure therapies
Sex-related similarities and differences in responses to heart failure therapies
Although sex-related differences in the epidemiology, risk factors, clinical characteristics and outcomes of heart failure...
Metabolic product of excess niacin is linked to increased risk of cardiovascular events
Metabolic product of excess niacin is linked to increased risk of cardiovascular events
A metabolic product of excess niacin promotes vascular inflammation in preclinical models and is associated with increased...
Novel drug therapies for atrial fibrillation
Novel drug therapies for atrial fibrillation
Atrial fibrillation is the most common sustained arrhythmia and imposes a substantial burden on patients and health-care p...
阅读更多
format_indent_increase