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Skin wound healing: of players, patterns and processes
Skin wound healing: of players, patterns and processes
Wound healing of the skin is a very complex biological activity. For a better understanding, an attempt is made to describ...
Regulation of FOXO3 on neuronal ferroptosis after intracerebral hemorrhage via modulating NOX4 transcription
Regulation of FOXO3 on neuronal ferroptosis after intracerebral hemorrhage via modulating NOX4 transcription
Introduction: Intracerebral hemorrhage (ICH) is known to trigger neuronal ferroptosis while forkhead box O3 (FOXO3) is imp...
Stepwise approach for acquisition of microsurgical skills through rat orthotopic liver transplantation experiments
Stepwise approach for acquisition of microsurgical skills through rat orthotopic liver transplantation experiments
Although rat liver transplantation (LT) is useful in training surgeons to perform microsurgery, mastering these surgical t...
DNA-Damage-Repair Gene Alterations in Genitourinary Malignancies
DNA-Damage-Repair Gene Alterations in Genitourinary Malignancies
<b><i>Background:</i></b> High-fidelity repair of DNA damage repair (DDR) (either single-strand- [...
Stem cell therapies for gastrointestinal anastomotic healing: a systematic review and meta-analysis on results from animal studies
Stem cell therapies for gastrointestinal anastomotic healing: a systematic review and meta-analysis on results from animal studies
Background: Despite considerable progress in surgical techniques, anastomotic leak (AL) is a common complication after gas...
Postoperative Severity Assessment in Sheep
Postoperative Severity Assessment in Sheep
<b><i>Introduction:</i></b> Sheep are frequently used in translational surgical orthopedic studies...
DNA damage repair genes alterations in genito-urinary malignancies
DNA damage repair genes alterations in genito-urinary malignancies
Background High-fidelity repair of DNA damage repair (DDR) [either single-strand- (SSBs) or double-strand breaks (DSBs)] i...
A novel combination of keratinocyte and autologous microskin grafting to repair full thickness skin loss
A novel combination of keratinocyte and autologous microskin grafting to repair full thickness skin loss
The high mortality of patients with extensive deep burns is mainly attributed to the extensive burn wound and scarce autol...
MUCOSAL RECOVERY  AFTER INTESTINAL TRANSPLANTATION IN THE RAT: A SEQUENTIAL HISTOLOGICAL AND MOLECULAR ASSESSMENT
MUCOSAL RECOVERY AFTER INTESTINAL TRANSPLANTATION IN THE RAT: A SEQUENTIAL HISTOLOGICAL AND MOLECULAR ASSESSMENT
Introduction Intestinal cold ischemia and subsequent reperfusion during transplantation result in various degrees of muco...
Post-operative severity assessment in sheep
Post-operative severity assessment in sheep
Introduction: Sheep are frequently used in translational surgical orthopedic studies. Naturally, a good pain management i...
THE LONG AND WINDING ROAD TO CLINICAL XENOTRANSPLANTATION – A PERSONAL JOURNEY
THE LONG AND WINDING ROAD TO CLINICAL XENOTRANSPLANTATION – A PERSONAL JOURNEY
The recent clinical pig heart transplant carried out at the University of Maryland in Baltimore is hopefully the first of ...
The open field test as a tool for behaviour analysis in pigs – recommendations for set-up standardisation. A systematic review.
The open field test as a tool for behaviour analysis in pigs – recommendations for set-up standardisation. A systematic review.
Introduction: The open field (OFT) test is a common tool to assess anxiety and behavioural changes in rodents. It has been...
Effect of gastrojejunostomy position on the postoperative amount of oral intake in pancreaticoduodenectomy
Effect of gastrojejunostomy position on the postoperative amount of oral intake in pancreaticoduodenectomy
Introduction We investigated the effect of the gastrojejunostomy position on the postoperative oral intake in patients who...
A Rat Model of Esophagogastric Anastomotic Stricture
A Rat Model of Esophagogastric Anastomotic Stricture
Esophagogastric anastomosis stricture is one of the most common postoperative complications after esophagectomy; yet, its ...
Welfare assessment on healthy and tumor-bearing mice after repeated ultrasound imaging
Welfare assessment on healthy and tumor-bearing mice after repeated ultrasound imaging
Introduction: Ultrasound (US) imaging enables tissue visualization in high spatial resolution with short examination time...
Severity assessment in rats undergoing subarachnoid hemorrhage induction by endovascular perforation or corresponding sham surgery
Severity assessment in rats undergoing subarachnoid hemorrhage induction by endovascular perforation or corresponding sham surgery
Introduction: Animal models for preclinical research of subarachnoid hemorrhage (SAH) are widely used as much of the patho...
Soluble urokinase receptor levels are not affected by the systemic inflammatory response to anesthesia and operative trauma
Soluble urokinase receptor levels are not affected by the systemic inflammatory response to anesthesia and operative trauma
Introduction: Soluble urokinase plasminogen activator receptor (suPAR) is an emerging biomarker of the level of chronic sy...
Treatment with the 5-Lipoxygenase Antagonist Zileuton Protects Mice from Postoperative Ileus
Treatment with the 5-Lipoxygenase Antagonist Zileuton Protects Mice from Postoperative Ileus
<b><i>Introduction:</i></b> Previous work of our group showed that lipoxygenase (LOX) pathways bec...
Blocking of CX3CL1 attenuates platelet and leukocyte recruitment in murine hepatic I/R
Blocking of CX3CL1 attenuates platelet and leukocyte recruitment in murine hepatic I/R
Background. The chemokine fractalkine (CX3CL1) is critically involved in the pathophysiology of different inflammatory dis...
Effects of Oral Pirfenidone on Colon Anastomosis Healing and Adhesion Formation in Rats
Effects of Oral Pirfenidone on Colon Anastomosis Healing and Adhesion Formation in Rats
Introduction: Many experimental studies have examined multiple drugs or treatments to improve the healing of intestinal an...