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Clinical validation of comprehensive complication index in pancreaticoduodenectomy
Clinical validation of comprehensive complication index in pancreaticoduodenectomy
Purpose Although the Clavien-Dindo classification (CDC) is the most widely utilized method for quantifying surgical compli...
Time-related Evidence of Intestinal Oxidative Stress in Obstructive Jaundice-Induced Rats
Time-related Evidence of Intestinal Oxidative Stress in Obstructive Jaundice-Induced Rats
Introduction: Obstructive jaundice is known to affect intestinal permeability and facilitate bacterial translocation throu...
Rapamycin does not act as a dietary restriction mimetic in the protection against ischemia reperfusion injury
Rapamycin does not act as a dietary restriction mimetic in the protection against ischemia reperfusion injury
Introduction Short-term fasting protects against renal ischemia reperfusion injury (IRI). mTOR signaling is downregulated ...
Editorial Animal Welfare: Severity Assessment in Experimental Research
Editorial Animal Welfare: Severity Assessment in Experimental Research
Animal experiments are indispensable in biomedical research [1, 2]. The use of animals for the sake of further development...
Analysis on Efficacy of Hepatic Artery Infusion Chemotherapy with or without Lenvatinib for Unresectable Hepatocellular Carcinoma
Analysis on Efficacy of Hepatic Artery Infusion Chemotherapy with or without Lenvatinib for Unresectable Hepatocellular Carcinoma
Background: For patients with advanced hepatocellular carcinoma (HCC), hepatic artery infusion chemotherapy (HAIC) is a co...
Predictive value of body composition parameters for postoperative complications in patients received pancreaticoduodenectomy
Predictive value of body composition parameters for postoperative complications in patients received pancreaticoduodenectomy
Introduction Sarcopenia and visceral obesity have been identified as risk factors for postoperative complications followin...
How surgical research gave birth to a new clinical surgical field: A viewpoint from the Dallas Uterus Transplant Study
How surgical research gave birth to a new clinical surgical field: A viewpoint from the Dallas Uterus Transplant Study
Background: Uterus transplantation (UTx) has come of age in the 21st Century, building on the 20th Century developments in...
Residents can do it! 
A hands-on training program in laparoscopic liver surgery for general surgery residents
Residents can do it!  A hands-on training program in laparoscopic liver surgery for general surgery residents
Introduction: Laparoscopic liver resections (LLR) constitute an area of surgery that has been kept away from residents in ...
Skin wound healing: of players, patterns and processes
Skin wound healing: of players, patterns and processes
Wound healing of the skin is a very complex biological activity. For a better understanding, an attempt is made to describ...
Regulation of FOXO3 on neuronal ferroptosis after intracerebral hemorrhage via modulating NOX4 transcription
Regulation of FOXO3 on neuronal ferroptosis after intracerebral hemorrhage via modulating NOX4 transcription
Introduction: Intracerebral hemorrhage (ICH) is known to trigger neuronal ferroptosis while forkhead box O3 (FOXO3) is imp...
Stepwise approach for acquisition of microsurgical skills through rat orthotopic liver transplantation experiments
Stepwise approach for acquisition of microsurgical skills through rat orthotopic liver transplantation experiments
Although rat liver transplantation (LT) is useful in training surgeons to perform microsurgery, mastering these surgical t...
DNA-Damage-Repair Gene Alterations in Genitourinary Malignancies
DNA-Damage-Repair Gene Alterations in Genitourinary Malignancies
<b><i>Background:</i></b> High-fidelity repair of DNA damage repair (DDR) (either single-strand- [...
Stem cell therapies for gastrointestinal anastomotic healing: a systematic review and meta-analysis on results from animal studies
Stem cell therapies for gastrointestinal anastomotic healing: a systematic review and meta-analysis on results from animal studies
Background: Despite considerable progress in surgical techniques, anastomotic leak (AL) is a common complication after gas...
Postoperative Severity Assessment in Sheep
Postoperative Severity Assessment in Sheep
<b><i>Introduction:</i></b> Sheep are frequently used in translational surgical orthopedic studies...
DNA damage repair genes alterations in genito-urinary malignancies
DNA damage repair genes alterations in genito-urinary malignancies
Background High-fidelity repair of DNA damage repair (DDR) [either single-strand- (SSBs) or double-strand breaks (DSBs)] i...
A novel combination of keratinocyte and autologous microskin grafting to repair full thickness skin loss
A novel combination of keratinocyte and autologous microskin grafting to repair full thickness skin loss
The high mortality of patients with extensive deep burns is mainly attributed to the extensive burn wound and scarce autol...
MUCOSAL RECOVERY  AFTER INTESTINAL TRANSPLANTATION IN THE RAT: A SEQUENTIAL HISTOLOGICAL AND MOLECULAR ASSESSMENT
MUCOSAL RECOVERY AFTER INTESTINAL TRANSPLANTATION IN THE RAT: A SEQUENTIAL HISTOLOGICAL AND MOLECULAR ASSESSMENT
Introduction Intestinal cold ischemia and subsequent reperfusion during transplantation result in various degrees of muco...