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Elevated iNOS and 3′-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model
Kaposi's Sarcoma (KS) is a heterogenous, multifocal vascular malignancy caused by the human herpesvirus 8 (HHV8), also kno...
Human papillomavirus genomics: Understanding carcinogenicity
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other anatomical sites in both men an...
Association of PNPLA3 (rs738409) & TM6SF2 (rs58542926) and ATG16L1 (rs2241880) genetic variants with susceptibility to hepatocellular carcinoma in a group of Egyptian patients with HCV-induced liver cirrhosis
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Molecular dissection of the E6 PBM identifies essential residues regulating Chk1 phosphorylation and subsequent 14-3-3 recognition
Previous studies have shown that the high-risk HPV E6 oncoprotein PDZ binding motifs (PBMs) can interact with PDZ proteins...
Exploring monitoring strategies for population surveillance of HPV vaccine impact using primary HPV screening
Australia's cervical screening program transitioned from cytology to HPV-testing with genotyping for HPV16/18 in Dec’2017....
The adenoviral E4orf3/4 is a regulatory polypeptide with cell transforming properties in vitro
The human adenovirus species C type 5 (HAdV-C5) early region 4 (E4) encodes several distinct polypeptides, defined as E4or...
Unresolved issues in the management of human papillomavirus-associated mucosal high-grade pre-cancers
This article reviews human papillomavirus-associated mucosal high-grade pre-cancers and their management. It examines pre-...
Synonymous nucleotide changes drive papillomavirus evolution
Papillomaviruses have been evolving alongside their hosts for at least 450 million years. This review will discuss some of...
Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients
BackgroundConsidering the immune evasion role of programmed death-ligand 1 (PD-L1) in cancer development, the genomic vari...
Differences in integration frequencies and APOBEC3 profiles of five high-risk HPV types adheres to phylogeny
Persistent infection with Human Papillomavirus (HPV) is responsible for almost all cases of cervical cancers, and HPV16 an...
Synergistic targeting of the PI3K/mTOR and MAPK/ERK pathways in Merkel cell carcinoma
Volume 14, December 2022, 200244AbstractMerkel cell carcinoma (MCC) is an aggressive type of skin cancer, which is caused ...
The oncogenic gamma herpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) hijack retinoic acid-inducible gene I (RIG-I) facilitating both viral and tumour immune evasion
Available online 20 August 2022, 200246AbstractHerpesviruses evade host immunity to establish persistent lifelong infectio...
HPV and head and neck cancers: Towards early diagnosis and prevention
Available online 13 August 2022, 200245AbstractHead and neck squamous cell carcinoma (HNSCC) is the sixth most common canc...
Detection of high-risk HPV in FFPE specimens of various tumours using the BD Onclarity™ HPV Assay
Available online 15 June 2022, 200243AbstractAnalysis of high-risk HPV status on formalin-fixed paraffin-embedded (FFPE) t...
Women with a positive high-risk human papillomavirus (HPV) test remain at increased risk of HPV infection and cervical precancer ≥15 years later
Available online 28 May 2022, 200240AbstractLittle is known about the long-term association between high-risk human papill...
Small DNA tumor viruses and human cancer: Preclinical models of virus infection and disease
Available online 27 May 2022, 200239AbstractHuman tumor viruses cause various human cancers that account for at least 15% ...
Human papillomavirus seroprevalence and seroconversion following baseline detection of nine human papillomavirus types in young women
Available online 4 May 2022, 200236Highlights•Research on humoral immune responses to HPV infection are limited.•HPV-relat...
Oral human papillomavirus prevalence, persistence, and risk-factors in HIV-positive and HIV-negative adults
Available online 20 April 2022, 200237AbstractBackgroundHIV has been shown to increase the likelihood of oral HPV infectio...
Cervical cancer therapies: current challenges and future perspectives
Available online 20 April 2022, 200238AbstractCervical cancer is the fourth most common female cancer worldwide and result...
Provider Preferences for Anal Cancer Prevention Screening: Results of the International Anal Neoplasia Society Survey
Available online 17 February 2022, 200235AbstractObjectiveThis study explores provider preferences regarding anal cancer s...
Increasing HPV vaccination coverage to prevent oropharyngeal cancer: A cost-effectiveness analysis
Volume 13, June 2022, 200234AbstractThe incidence of oropharyngeal cancer (OPC) has been rising, especially among middle-a...
Increasing HPV Vaccination Coverage on Preventing Oropharyngeal Cancer: A Cost-Effectiveness Analysis
Available online 30 December 2021, 200234AbstractThe incidence of oropharyngeal cancer (OPC) has been rising, especially a...
The association between viral load and concurrent human papillomavirus infection at the genital and anal sites of young women and the impact of vaccination
Concurrent genital-anal human papillomavirus (HPV) infections may impose an increased anal cancer risk in women with HPV-r...
Oesophageal carcinoma: the prevalence of DNA tumour viruses and therapy
Oesophageal carcinoma ranks the sixth leading cause of cancer death and affected 544,000 - 604,000 people in 2020. Patient...
Merkel cell polyomavirus and associated Merkel cell carcinoma
Available online 15 December 2021, 200232AbstractMerkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can ...
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Welcome to Tumour Virus Research
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Harnessing immunity for therapy in human papillomavirus driven cancers
Volume 11, June 2021, 200212AbstractIn persistent high-risk HPV infection, viral gene expression can trigger some importan...
Human papillomavirus E6 and E7: What remains?
Volume 11, June 2021, 200213AbstractDecades of research on the human papillomavirus oncogenes, E6 and E7, have given us hu...
Development and evaluation of an online continuing education course to increase healthcare provider self-efficacy to make strong HPV vaccine recommendations to East African immigrant families
Volume 11, June 2021, 200214Highlights•Online continuing education targeted HPV vaccination in East African communities.•E...
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