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Septic arthritis in an in vivo murine model induced by Staphylococcus aureus
Septic arthritis in an in vivo murine model induced by Staphylococcus aureus
AimsStaphylococcus aureus is a major cause of septic arthritis, and in vitro studies suggest α haemolysin (Hla) is respons...
Diagnosing periprosthetic joint infections
Diagnosing periprosthetic joint infections
AimsThis study evaluated the definitions developed by the European Bone and Joint Infection Society (EBJIS) 2021, the Inte...
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms
Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms
AimsHere we used a mature seven-day biofilm model of Staphylococcus aureus, exposed to antibiotics up to an additional sev...
Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty
Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty
AimsThe aim of this study was to report the meaningful values of the EuroQol five-dimension three-level questionnaire (EQ-...
Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor
Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor
AimsOsteoarthritis (OA) is a common degenerative joint disease characterized by chronic inflammatory articular cartilage d...
The effect of anti-retroviral therapy on fracture healing
The effect of anti-retroviral therapy on fracture healing
AimsA number of anti-retroviral therapies (ART) have been implicated in potentially contributing to HIV-associated bone di...
The epidemiology and direct healthcare costs of aseptic nonunions in Germany – a descriptive report
The epidemiology and direct healthcare costs of aseptic nonunions in Germany – a descriptive report
AimsThis observational cross-sectional study aimed to answer the following questions: 1) how has nonunion incidence develo...
Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis
Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis
AimsWe aimed to develop a gene signature that predicts the occurrence of postmenopausal osteoporosis (PMOP) by studying it...
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon
Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the Achilles tendon
Tendon is a bradytrophic and hypovascular tissue, hence, healing remains a major challenge. The molecular key events invol...
The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty
The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty
AimsThe aim of this study was to determine the risk of tibial eminence avulsion intraoperatively for bi-unicondylar knee a...
Animal models of osteoarthritis
Animal models of osteoarthritis
Cite this article: Bone Joint Res 2022;11(8):514–517.
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope
Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope
AimsTo evaluate inducing osteoarthritis (OA) by surgical destabilization of the medial meniscus (DMM) in mice with and wit...
Analysis of combined deficiency of interleukin-1 and -6 versus single deficiencies in TNF-mediated arthritis and systemic bone loss
Analysis of combined deficiency of interleukin-1 and -6 versus single deficiencies in TNF-mediated arthritis and systemic bone loss
Aims Insufficient treatment response in rheumatoid arthritis (RA) patients requires novel treatment strategies to halt dis...
Osteocyte-specific dentin matrix protein 1
Osteocyte-specific dentin matrix protein 1
Aims There is an increasing concern of osteoporotic fractures in the ageing population. Low-magnitude high-frequency vibra...
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis
GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis
Aims Abnormal lipid metabolism is involved in the development of osteoarthritis (OA). Growth differentiation factor 11 (GD...
Peripheral nerves in the tibial subchondral bone
Peripheral nerves in the tibial subchondral bone
Osteoarthritis (OA) is a highly prevalent degenerative joint disorder characterized by joint pain and physical disability....
Immunomodulatory role of T helper cells in rheumatoid arthritis
Immunomodulatory role of T helper cells in rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that involves T and B cells and their reciprocal immune interactions wi...