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Comparison of the effect of intravenous dexamethasone and methylprednisolone on the treatment of hospitalized patients with COVID-19: A randomized clinical trial
Highlights•Dexamethasone was more effective than methylprednisolone for covid-19.•Hospitalization time was shorter in the ...
Susceptibility to endemic Aedes-borne viruses among pregnant women in Risaralda, Colombia
AbstractObjective: Aedes-borne viruses (ABV) affect humans on every inhabited continent and frequently cause epidemics. Re...
Letter to the Editor: Failure to account for population size introduces spurious correlation for almost all diseases at a country level
Countries differ by size [1].Because of this, total cumulative counts of most diseases at a country level will be spurious...
Use of broad-spectrum antibiotics in children diagnosed with multisystem inflammatory syndrome temporarily associated with SARS-CoV-2 infection in Poland: the MOIS-CoR study
AbstractObjectives: Multisystem Inflammatory Syndrome in Children (MIS-C) is the result of an immune response triggered by...
Ct values as a diagnostic tool for monitoring SARS-CoV-2 viral load using the QIAstat-Dx® Respiratory SARS-CoV-2 Panel
Highlights•Use of the Ct value as a proxy of viral load with patient outcomes is under debate•The QIAstat-Dx SARS-CoV-2 as...
Pharmacokinetics and Safety of WHO-recommended Dosage and Higher Dosage of Levofloxacin for Tuberculosis Treatment in Children: A pilot study
AbstractObjectives: To evaluate the pharmacokinetic (PK) parameters of the 2020 WHO-recommended pediatric dosage of levofl...
Atypical pneumonia caused by Chlamydia Psittaci during the COVID-19 pandemic
AbstractObjectives: Here, we retrospectively describe the diagnosis and treatment of thirty-two cases diagnosed with Chlam...
Short and long-term immune changes in different severity groups of COVID-19 disease
Highlights•Moderate and severe/critical groups had high inflammation at presentation.•Inflammation did not normalise for t...
SARS-CoV-2 Reinfection Rate and Outcomes in Saudi Arabia: A National Retrospective Study
Highlights•SARS-CoV-2 reinfection estimated at 0.8% over a 20-month follow-up in Saudi Arabia.•Diabetes, HIV, obesity and ...
A case of immune complex type hemolytic anemia by initial micafungin administration
HighlightsAbstractWe report the first case of immune complex type hemolytic anemia by initial micafungin administration th...
Annular rupioid secondary syphilis confined to the face
AbstractSyphilis is a sexually transmitted infection (STI) caused by treponema pallidum. Its rash usually affects the trun...
Ceftriaxone-induced encephalopathy in a patient with a solitary kidney
Highlights•CRO administration can cause encephalopathy due to high blood levels of CRO•The CRO concentration in blood at t...
Risk factors for late linkage to care and delayed antiretroviral therapy initiation amongst HIV infected adults in sub-Saharan Africa: a systematic review and meta-analyses
Highlights•Variation in HIV care linkage/treatment initiation across nations/settings in SSA•Low HIV care linkage and trea...
Colonization of the Newborn Respiratory Tract and Its Association with Respiratory Morbidity in the first six months of life: A Prospective Cohort Study
ABSTRACTObjectiveWe aimed to determine the association between newborn bacterial colonization and infant respiratory morbi...
Cytomegalovirus viremia as a risk factor for mortality in HIV-associated cryptococcal and tuberculous meningitis
AbstractObjectives: Cytomegalovirus (CMV) viremia is associated with increased mortality in persons with HIV. We previousl...
Development and Clinical Application of a Rapid and Visual Loop-Mediated Isothermal Amplification Test for tetM gene in Clostridioides difficile Strains Cultured from Feces
AbstractObjectivesTo develop a rapid and visual loop-mediated isothermal amplification (LAMP) assay targeting the tetM gen...
Effectiveness of BBV152/Covaxin and AZD1222/Covishield vaccines against severe COVID-19 and B.1.617.2/Delta variant in India, 2021: A multi-centric hospital-based case-control study
DiscussionThe results from this large multicentric study indicate that both AZD1222/Covishield and BBV152/Covaxin signific...
Possible Sex Difference in Latent Tuberculosis Infection Risk among Close Tuberculosis Contacts
AbstractBackgroundMore men than women develop and die of tuberculosis (TB). Fewer data exist on sex differences in latent ...
Monoclonal Antibody Therapy in a Vaccine Breakthrough SARS-CoV-2 Hospitalized Delta (B.1.617.2) Variant Case
Highlights•Vaccine breakthrough of father and son living in separate households•Delta (B.1.617.2) variant vaccine breakthr...
nnAge significantly influences the sensitivity of SARS-CoV-2 rapid antibody assays
ABSTRACTBACKGROUNDPoint of care serological assays are a promising tool in COVID-19 diagnostics but do have limitations. T...
Proteinuria in Hantavirus Cardiopulmonary Syndrome: a frequent finding linked to mortality
Highlights•Clinical relevance of proteinuria in Andes virus is poorly understood•Proteinuria is a frequent finding in Hant...
Autochthonous leprosy in Europe: a case report and literature review
AbstractLeprosy is currently uncommon in Europe: the diagnosed cases are almost allimported from endemic areas. We report ...
Reduction in COVID-19 prevalence in health care workers in a university hospital in southern Brazil after the start of vaccination.
Highlights•Vaccines are able to reduce the infection and severity of COVID-19.•There is a possibility of infection after v...
Assessment of Interferon Gamma-Induced Protein 10 mRNA Release Assay for Detection of Latent Tuberculosis Infection in Egyptian Pediatric Household Contacts
Abdulkareem FN Merza MA Salih AM. First insight into latent tuberculosis infection among household contacts of tuberculosi...
Incident detection of human papillomavirus – a prospective follow-up study among Tanzanian women with focus on HIV status
INTRODUCTIONDespite being preventable, the cervical cancer burden remains a significant public health concern globally. Hu...
Safety and Efficacy of a 5-Minute Infusion versus the Standard 30-minute Infusion for Antibiotics in an Outpatient Setting
Highlights•We studied the rapid infusion of ceftriaxone, ertapenem, meropenem and daptomycin.•There were no rapid infusion...
High seroprevalence for SARS-CoV-2 infection in South America, but still not enough for heard immunity!
Table 1SARS-CoV-2 seroprevalence in South American populations.95% CI, 95% confidence interval; ELISA, enzyme-linked immun...
Large epidemic of a necrotic skin infection in the Democratic Republic of São Tomé and Principe: an epidemiological study
IntroductionCellulitis is a common infection of the skin associated with swelling, erythema, and pain of the affected area...
SARS-CoV-2: Viral Loads of Exhaled Breath and Oronasopharyngeal Specimens in Hospitalized Patients with COVID-19
IntroductionThe continuous dissemination of SARS-CoV-2 has emerged as a global health threat due to its high risk of trans...
Diagnostic accuracy of a SARS-CoV-2 rapid antigen test in real-life clinical settings
Highlights•High hopes are placed on SARS-CoV-2 rapid antigen tests•The diagnostic accuracy in clinical settings is essenti...
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