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Unfractionated heparin attenuated histone-induced pulmonary endothelial glycocalyx injury through Ang/Tie2 pathway
Unfractionated heparin attenuated histone-induced pulmonary endothelial glycocalyx injury through Ang/Tie2 pathway
This study aimed to investigate the involvement of angiopoietin (Ang)/Tie2 pathway in mediating pulmonary endothelial glyc...
Correction: Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis
Correction: Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Auto-antibodies against carbonyl-modified vimentin in COPD: potential role as a biomarker
Auto-antibodies against carbonyl-modified vimentin in COPD: potential role as a biomarker
COPD has many hallmarks of autoimmune dysfunction. Driving this autoimmune response are self-antigens, such as highly abun...
Alpha-1 antitrypsin reduces inflammation and vasculopathy in mice with oxygen-induced retinopathy
Alpha-1 antitrypsin reduces inflammation and vasculopathy in mice with oxygen-induced retinopathy
Damage to the retinal vasculature is a major cause of vision loss and is influenced by a pro-inflammatory environment with...
Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice
Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice
Subretinal injections provide direct access to photoreceptors and RPE, which is crucial for the delivery of gene therapy a...
The injury effect of osteopontin in sepsis-associated lung injury
The injury effect of osteopontin in sepsis-associated lung injury
Sepsis is a severe condition causing organ failure due to an abnormal immune reaction to infection, characterized by ongoi...
TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B
TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B
Clostridioides difficile, a spore-forming anaerobic bacterium, is the primary cause of hospital antibiotic-associated diar...
Correction: Downregulation of miR-223 promotes HMGB2 expression and induces oxidative stress to activate JNK and promote autophagy in an in vitro model of acute lung injury
Correction: Downregulation of miR-223 promotes HMGB2 expression and induces oxidative stress to activate JNK and promote autophagy in an in vitro model of acute lung injury
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Progress of CCL20-CCR6 in the airways: a promising new therapeutic target
Progress of CCL20-CCR6 in the airways: a promising new therapeutic target
The chemokine CCL20, a small cytokine that belongs to the C–C chemokine family, interacts with its homologous recept...
Basement membranes’ role in immune cell recruitment to the central nervous system
Basement membranes’ role in immune cell recruitment to the central nervous system
Basement membranes form part of the extracellular matrix (ECM), which is the structural basis for all tissue. Basement mem...
Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis
Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis
Pathogenesis of atherosclerosis is largely mediated by inflammatory process. Statins are lipid-lowering drugs which also h...
Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins
Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins
HMG-CoA reductase inhibitors are well-known medications in the treatment of cardiovascular disorders due to their pleiotro...
Resolution of acute inflammation induced by monosodium urate crystals (MSU) through neutrophil extracellular trap-MSU aggregate-mediated negative signaling
Resolution of acute inflammation induced by monosodium urate crystals (MSU) through neutrophil extracellular trap-MSU aggregate-mediated negative signaling
Polymorphonuclear neutrophils (PMN) activation by monosodium urate crystals (MSU) is crucial to acute gouty arthritis and ...
Non-ionic surfactant vesicles exert anti-inflammatory effects through inhibition of NFκB
Non-ionic surfactant vesicles exert anti-inflammatory effects through inhibition of NFκB
Inflammation can be an unwanted consequence or cause of debilitating diseases of infectious and non-infectious aetiologies...
Macrophage involvement in idiopathic inflammatory myopathy: pathogenic mechanisms and therapeutic prospects
Macrophage involvement in idiopathic inflammatory myopathy: pathogenic mechanisms and therapeutic prospects
Idiopathic inflammatory myopathies are a group of systemic autoimmune diseases characterized by chronic muscle inflammatio...
Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes
Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes
Sepsis-induced myocardial dysfunction (SIMD) may contribute to the poor prognosis of septic patients. Carvacrol (2-methyl-...
Correction: Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response
Correction: Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Unveiling the hidden world of transfer RNA-derived small RNAs in inflammation
Unveiling the hidden world of transfer RNA-derived small RNAs in inflammation
Transfer RNA-derived small RNAs (tsRNAs) are a newly discovered class of small noncoding RNAs (sncRNAs) that include tRNA-...
Clinical, pharmacology and in vivo studies of QingDai (indigo naturalis) promotes mucosal healing and symptom improvement in ulcerative colitis by regulating the AHR-Th17/Treg pathway
Clinical, pharmacology and in vivo studies of QingDai (indigo naturalis) promotes mucosal healing and symptom improvement in ulcerative colitis by regulating the AHR-Th17/Treg pathway
Qingdai (QD), derived from various plant sources, is commonly used in traditional Chinese medicine for ulcerative colitis ...
Regulatory role of microRNAs in virus-mediated inflammation
Regulatory role of microRNAs in virus-mediated inflammation
Viral infections in humans often cause excessive inflammation. In some viral infections, inflammation can be serious and e...
Profile of immune response during nasal challenge with dermatophagoides pteronyssinus in subjects with allergic airway diseases
Profile of immune response during nasal challenge with dermatophagoides pteronyssinus in subjects with allergic airway diseases
T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed th...
Influence and distinctions of particulate matter exposure across varying etiotypes in chronic obstructive pulmonary disease (COPD) mouse model
Influence and distinctions of particulate matter exposure across varying etiotypes in chronic obstructive pulmonary disease (COPD) mouse model
Air pollution, notably particulate matter (PM), significantly impacts chronic respiratory disease such chronic obstructive...
Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis
Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis
Trauma and infection induce emergency granulopoiesis. Counts of immature granulocytes and transcriptional pathways of term...
Locomotor and gait changes in the LPS model of neuroinflammation are correlated with inflammatory cytokines in blood and brain
Locomotor and gait changes in the LPS model of neuroinflammation are correlated with inflammatory cytokines in blood and brain
Lipopolysaccharide (LPS) challenge in mice has been used to identify the mechanisms and therapeutics for neuroinflammation...
Correction: Disulfiram Alleviates Acute Lung Injury and Related Intestinal Mucosal Barrier Impairment by Targeting GSDMD-Dependent Pyroptosis
Correction: Disulfiram Alleviates Acute Lung Injury and Related Intestinal Mucosal Barrier Impairment by Targeting GSDMD-Dependent Pyroptosis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway
Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway
The kidney is exceptionally vulnerable during sepsis, often resulting in sepsis-associated acute kidney injury (SA-AKI), a...
Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis
Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis
Rheumatoid arthritis (RA) is associated with a high concentration of extracellular DNA (ecDNA). This could be a consequenc...
Sonic Hedgehog reduces inflammatory response, decreases blood-spinal cord barrier permeability, and improves locomotor function recovery in an acute spinal cord injury rat model
Sonic Hedgehog reduces inflammatory response, decreases blood-spinal cord barrier permeability, and improves locomotor function recovery in an acute spinal cord injury rat model
Sonic Hedgehog (Shh), extensively researched for its role in early neurogenesis and brain development, has recently been r...
Correction: PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role
Correction: PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
The effects of chronic, continuous β-funaltrexamine pre-treatment on lipopolysaccharide-induced inflammation and behavioral deficits in C57BL/6J mice
The effects of chronic, continuous β-funaltrexamine pre-treatment on lipopolysaccharide-induced inflammation and behavioral deficits in C57BL/6J mice
Inflammation and neuroinflammation are integral to the progression and severity of many diseases and are strongly associat...
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