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The immunological function of CXCR2 in the liver during sepsis
The immunological function of CXCR2 in the liver during sepsis
The chemokine receptor CXCR2 and its ligands, especially CXCL8, are crucial mediators for the progression of liver inflamm...
Neutrophil reverse migration
Neutrophil reverse migration
The behavior of neutrophils is very important for the resolution of inflammation and tissue repair. People have used advan...
Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype
Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype
Macrophages are effector cells of the innate immune system that undergo phenotypical changes in response to organ injury a...
Induction of pyroptotic cell death as a potential tool for cancer treatment
Induction of pyroptotic cell death as a potential tool for cancer treatment
Cancer is a complex pathological disease and the existing strategies for introducing chemotherapeutic agents have restrict...
Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice
Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice
Chronic inflammation and oxidant/antioxidant imbalance are two main pathological features associated with lipopolysacchari...
Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis
Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis
Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhib...
Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology
Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology
With the incidence of hypertension increasing worldwide, more and more the mechanisms of hypertension from the perspective...
SILAC-based quantitative proteomics to investigate the eicosanoid associated inflammatory response in activated macrophages
SILAC-based quantitative proteomics to investigate the eicosanoid associated inflammatory response in activated macrophages
Macrophages play a central role in inflammation by phagocytosing invading pathogens, apoptotic cells and debris, as well a...
Single-cell RNA-seq data analysis characterizing bronchoalveolar epithelial cells in patients with SARS-CoV-2 infection
Single-cell RNA-seq data analysis characterizing bronchoalveolar epithelial cells in patients with SARS-CoV-2 infection
Angiotensin-converting enzyme 2 (ACE2) has been reported to be the main receptor for SARS-CoV-2 infection of host cells. U...
Recent evidence from omic analysis for redox signalling and mitochondrial oxidative stress in COPD
Recent evidence from omic analysis for redox signalling and mitochondrial oxidative stress in COPD
COPD is driven by exogenous and endogenous oxidative stress derived from inhaled cigarette smoke, air pollution and reacti...
Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury
Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury
Severe sepsis and its subsequent complications cause high morbidity and mortality rates worldwide. The lung is one of the ...
Key early proinflammatory signaling molecules encapsulated within circulating exosomes following traumatic injury
Key early proinflammatory signaling molecules encapsulated within circulating exosomes following traumatic injury
Assessment of immune status in critically ill patients is often based on serial tracking of systemic cytokine levels and c...
CircRNA circFADS2 is under-expressed in sepsis and protects lung cells from LPS-induced apoptosis by downregulating miR-133a
CircRNA circFADS2 is under-expressed in sepsis and protects lung cells from LPS-induced apoptosis by downregulating miR-133a
It has been reported that hsa_circRNA_100833 (identified as circFADS2) and miR-133a play opposite roles in LPS-induced cel...
The effects of two different dietary regimens during exercise on outcome of experimental acute kidney injury
The effects of two different dietary regimens during exercise on outcome of experimental acute kidney injury
Acute kidney injury (AKI) is a syndrome characterized by rapid loss of excretory function of kidney. Both exercise and som...
TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis
TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis
TRIP6 is a zyxin family member that serves as an adaptor protein to regulate diverse biological processes. In prior report...
Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis
Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis
Studies have shown that ginsenoside R3 (Rg3) plays a protective role in sepsis-induced organ injuries and mitochondrial dy...
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
TGF-β and its receptors play a crucial role in asthma pathogenesis, bronchial hyperreactivity, and bronchial remodeli...