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Identification and validation of biomarkers related to Th1 cell infiltration in neuropathic pain
Identification and validation of biomarkers related to Th1 cell infiltration in neuropathic pain
Neuropathic pain (NP) is a widespread chronic pain with a prevalence of 6.9–10% in the general population, severely ...
Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis
Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis
To perform a systematic literature review and meta-analysis on endothelial cell (EC) markers that are involved and dysregu...
Neutrophil extracellular traps in acute coronary syndrome
Neutrophil extracellular traps in acute coronary syndrome
Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart ...
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study
Osteoarthritis (OA) is a common joint disease and is the main cause of physical disability in the elderly. Currently, ther...
Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury
Efficacy of CU06-1004 via regulation of inflammation and endothelial permeability in LPS-induced acute lung injury
Acute lung injury (ALI) is a life-threatening condition that fundamentally results from inflammation and edema in the lung...
Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance
Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can be asymptomatic or cause a disease (COVID-1...
Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ
Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ
Chronic low-grade inflammation has been identified as a major contributor in the development of atherosclerosis. Nuclear F...
C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice
C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice
Lower respiratory infections caused by ssRNA viruses are a major health burden globally. Translational mouse models are a ...
Tofacitinib reduces acute lung injury and improves survival in a rat model of sepsis by inhibiting the JAK-STAT/NF-κB pathway
Tofacitinib reduces acute lung injury and improves survival in a rat model of sepsis by inhibiting the JAK-STAT/NF-κB pathway
Acute lung injury is a major cause of death in sepsis. Tofacitinib (TOFA), a JAK inhibitor, has anti-inflammatory activity...
Anti-inflammatory effects of β-FNA are sex-dependent in a pre-clinical model of LPS-induced inflammation
Anti-inflammatory effects of β-FNA are sex-dependent in a pre-clinical model of LPS-induced inflammation
Inflammation is present in neurological and peripheral disorders. Thus, targeting inflammation has emerged as a viable opt...
Neutrophil extracellular traps and pulmonary fibrosis: an update
Neutrophil extracellular traps and pulmonary fibrosis: an update
Pulmonary fibrosis (PF) is a serious and often fatal illness that occurs in various clinical settings and represents a sig...
Progranulin (PGRN) as a regulator of inflammation and a critical factor in the immunopathogenesis of cardiovascular diseases
Progranulin (PGRN) as a regulator of inflammation and a critical factor in the immunopathogenesis of cardiovascular diseases
Immune dysregulation has been identified as a critical cause of the most common types of cardiovascular diseases (CVDs). N...
Evaluation of asthma–chronic obstructive pulmonary disease overlap using a mouse model of pulmonary disease
Evaluation of asthma–chronic obstructive pulmonary disease overlap using a mouse model of pulmonary disease
Features of asthma and chronic obstructive pulmonary disease (COPD) can coexist in the same patient, in a condition termed...
The immunological function of CXCR2 in the liver during sepsis
The immunological function of CXCR2 in the liver during sepsis
The chemokine receptor CXCR2 and its ligands, especially CXCL8, are crucial mediators for the progression of liver inflamm...
Neutrophil reverse migration
Neutrophil reverse migration
The behavior of neutrophils is very important for the resolution of inflammation and tissue repair. People have used advan...
Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype
Protein arginine deiminase 2 (PAD2) modulates the polarization of THP-1 macrophages to the anti-inflammatory M2 phenotype
Macrophages are effector cells of the innate immune system that undergo phenotypical changes in response to organ injury a...
Induction of pyroptotic cell death as a potential tool for cancer treatment
Induction of pyroptotic cell death as a potential tool for cancer treatment
Cancer is a complex pathological disease and the existing strategies for introducing chemotherapeutic agents have restrict...