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Engineering dendritic cell biomimetic membrane as a delivery system for tumor targeted therapy
Engineering dendritic cell biomimetic membrane as a delivery system for tumor targeted therapy
Targeted immunotherapies make substantial strides in clinical cancer care due to their ability to counteract the tumor'...
Magnetic vagus nerve stimulation ameliorates contrast-induced acute kidney injury by circulating plasma exosomal miR-365-3p
Magnetic vagus nerve stimulation ameliorates contrast-induced acute kidney injury by circulating plasma exosomal miR-365-3p
Contrast-induced acute kidney injury (CI-AKI) is manifested by a rapid decline in renal function occurring within 48–...
Macrophage membrane-functionalized manganese dioxide nanomedicine for synergistic treatment of atherosclerosis by mitigating inflammatory storms and promoting cholesterol efflux
Macrophage membrane-functionalized manganese dioxide nanomedicine for synergistic treatment of atherosclerosis by mitigating inflammatory storms and promoting cholesterol efflux
Atherosclerosis (AS) poses a significant threat to human life and health. However, conventional antiatherogenic medication...
Magnetic targeting enhances the neuroprotective function of human mesenchymal stem cell-derived iron oxide exosomes by delivering miR-1228-5p
Magnetic targeting enhances the neuroprotective function of human mesenchymal stem cell-derived iron oxide exosomes by delivering miR-1228-5p
Treating mitochondrial dysfunction is a promising approach for the treatment of post-stroke cognitive impairment (PSCI). H...
Copper hydrogen phosphate nanosheets functionalized hydrogel with tissue adhesive, antibacterial, and angiogenic capabilities for tracheal mucosal regeneration
Copper hydrogen phosphate nanosheets functionalized hydrogel with tissue adhesive, antibacterial, and angiogenic capabilities for tracheal mucosal regeneration
Timely and effective interventions after tracheal mucosal injury are lack in clinical practices, which elevate the risks o...
Maternal exposure to nanopolystyrene induces neurotoxicity in offspring through P53-mediated ferritinophagy and ferroptosis in the rat hippocampus
Maternal exposure to nanopolystyrene induces neurotoxicity in offspring through P53-mediated ferritinophagy and ferroptosis in the rat hippocampus
There are increasing concerns regarding the rapid expansion of polystyrene nanoplastics (PS-NPs), which could impact human...
Photoimmunotherapy using indocyanine green-loaded Codium fragile polysaccharide and chitosan nanoparticles suppresses tumor growth and metastasis
Photoimmunotherapy using indocyanine green-loaded Codium fragile polysaccharide and chitosan nanoparticles suppresses tumor growth and metastasis
Metastasis and recurrence are the main challenges in cancer treatment. Among various therapeutic approaches, immunotherapy...
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia
Animal and human health are seriously threatened by bacterial infections, which can lead to bacteremia and extremely high ...
Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation
Curcumin/pEGCG-encapsulated nanoparticles enhance spinal cord injury recovery by regulating CD74 to alleviate oxidative stress and inflammation
Spinal cord injury (SCI) often accompanies impairment of motor function, yet there is currently no highly effective treatm...
A novel anti-CTLA-4 nanobody-IL12 fusion protein in combination with a dendritic cell/tumour fusion cell vaccine enhances the antitumour activity of CD8+ T cells in solid tumours
A novel anti-CTLA-4 nanobody-IL12 fusion protein in combination with a dendritic cell/tumour fusion cell vaccine enhances the antitumour activity of CD8+ T cells in solid tumours
We previously developed a nanobody targeting CTLA-4 and demonstrated that it can boost antitumour T-cell responses in vitr...
Single-atom nanozyme liposome-integrated microneedles for in situ drug delivery and anti-inflammatory therapy in Parkinson’s disease
Single-atom nanozyme liposome-integrated microneedles for in situ drug delivery and anti-inflammatory therapy in Parkinson’s disease
Treatment for Parkinson’s disease (PD) has been impeded by inefficient treatment results and multiple membrane barri...
Lactobacillus rhamnosus GG-derived extracellular vesicles promote wound healing via miR-21-5p-mediated re-epithelization and angiogenesis
Lactobacillus rhamnosus GG-derived extracellular vesicles promote wound healing via miR-21-5p-mediated re-epithelization and angiogenesis
Extracellular vesicles (EVs), especially those derived from stem cells, have emerged as a novel treatment for promoting wo...
A novel biomimetic nanovesicle containing caffeic acid-coupled carbon quantum dots for the the treatment of Alzheimer’s disease via nasal administration
A novel biomimetic nanovesicle containing caffeic acid-coupled carbon quantum dots for the the treatment of Alzheimer’s disease via nasal administration
Alzheimer’s disease (AD) is a common neurodegenerative disease characterized by progressive cognitive and physical i...
From ROS scavenging to boosted osseointegration: cerium-containing mesoporous bioactive glass nanoparticles functionalized implants in diabetes
From ROS scavenging to boosted osseointegration: cerium-containing mesoporous bioactive glass nanoparticles functionalized implants in diabetes
Excessive production of reactive oxygen species (ROS) around titanium implants under diabetic conditions causes persistent...
Stable triangle: nanomedicine-based synergistic application of phototherapy and immunotherapy for tumor treatment
Stable triangle: nanomedicine-based synergistic application of phototherapy and immunotherapy for tumor treatment
In recent decades, cancer has posed a challenging obstacle that humans strive to overcome. While phototherapy and immunoth...
Unlocking nature’s brilliance: using Antarctic extremophile Shewanella baltica to biosynthesize lanthanide-containing nanoparticles with optical up-conversion
Unlocking nature’s brilliance: using Antarctic extremophile Shewanella baltica to biosynthesize lanthanide-containing nanoparticles with optical up-conversion
Both lanthanide-containing and fluorine-containing nanomaterials present challenging targets for microbial biosynthesis be...
Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells
Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells
Intervertebral disc degeneration (IVDD) is a prevalent musculoskeletal disorder that involves the excessive accumulation o...
Layer by layer self-assembled hyaluronic acid nanoarmor for the treatment of ulcerative colitis
Layer by layer self-assembled hyaluronic acid nanoarmor for the treatment of ulcerative colitis
Natural compound-based treatments provide innovative ways for ulcerative colitis therapy. However, poor targeting and rapi...
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury
Neutrophil N1 polarization induced by cardiomyocyte-derived extracellular vesicle miR-9-5p aggravates myocardial ischemia/reperfusion injury
Neutrophil polarization contributes to inflammation and its resolution, but the role of neutrophil polarization in myocard...
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts
The hypertrophic scar (HS) is a prevalent cutaneous fibrotic disorder that impacts both the aesthetic and functional aspec...
Recombinant Lactococcus lactis secreting FliC protein nanobodies for resistance against Salmonella enteritidis invasion in the intestinal tract
Recombinant Lactococcus lactis secreting FliC protein nanobodies for resistance against Salmonella enteritidis invasion in the intestinal tract
Salmonella Enteritidis is a major foodborne pathogen throughout the world and the increase in antibiotic resistance of Sal...
Colostrum-derived extracellular vesicles: potential multifunctional nanomedicine for alleviating mastitis
Colostrum-derived extracellular vesicles: potential multifunctional nanomedicine for alleviating mastitis
Bovine mastitis is an infectious disease that causes substantial economic losses to the dairy industry worldwide. Current ...
Hypoxic glioma-derived exosomal miR-25-3p promotes macrophage M2 polarization by activating the PI3K-AKT-mTOR signaling pathway
Hypoxic glioma-derived exosomal miR-25-3p promotes macrophage M2 polarization by activating the PI3K-AKT-mTOR signaling pathway
Exosomes (EXO) play crucial roles in intercellular communication and glioma microenvironment modulation. Tumor-associated ...
Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium
Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics, and modulating inflammatory r...
Conformal immunomodulatory hydrogels for the treatment of otitis media
Conformal immunomodulatory hydrogels for the treatment of otitis media
Otitis media (OM), a condition stemming from the proliferation of various bacteria within the tympanic cavity (TC), is com...
Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing
Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing
Diabetes is a global chronic disease that seriously endangers human health and characterized by abnormally high blood gluc...
Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizosphere bacterial community
Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizosphere bacterial community
Tomato (Solanum lycopersicum L.) production is severely threatened by bacterial wilt, caused by the phytopathogenic bacter...
Chemical screens for particle-induced macrophage death identifies kinase inhibitors of phagocytosis as targets for toxicity
Chemical screens for particle-induced macrophage death identifies kinase inhibitors of phagocytosis as targets for toxicity
Nanoparticles are increasingly being used in medicine, cosmetics, food, and manufacturing. However, potential toxicity may...
Correction: Conductive single-wall carbon nanotubes/extracellular matrix hybrid hydrogels promote the lineage-specific development of seeding cells for tissue repair through reconstructing an integrin-dependent niche
Correction: Conductive single-wall carbon nanotubes/extracellular matrix hybrid hydrogels promote the lineage-specific development of seeding cells for tissue repair through reconstructing an integrin-dependent niche
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Construction of in-situ self-assembled agent for NIR/PET dual-modal imaging and photodynamic therapy for hepatocellular cancer
Construction of in-situ self-assembled agent for NIR/PET dual-modal imaging and photodynamic therapy for hepatocellular cancer
Hepatocellular cancer (HCC) remained a life-threatening carcinoma. Agents for HCC imaging and therapy were expected to pos...
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