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Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer’s disease
Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer’s disease
The global demographic shift towards an aging population is generating a rise in neurodegenerative conditions, with Alzhei...
Fluorescence sensor array for highly sensitive pattern recognition of biothiols in food based on tricolor upconversion luminescence metal-organic frameworks
Fluorescence sensor array for highly sensitive pattern recognition of biothiols in food based on tricolor upconversion luminescence metal-organic frameworks
Fluorescence nanomaterial sensors have exhibited excellent application potential in biothiols analyses. The fluorescence s...
Precision management of Fusarium fujikuroi in rice through seed coating with an enhanced nanopesticide using a tannic acid-ZnII formulation
Precision management of Fusarium fujikuroi in rice through seed coating with an enhanced nanopesticide using a tannic acid-ZnII formulation
Seed coating with fungicides is a common practice in controlling seed-borne diseases, but conventional methods often resul...
IL-7 promotes mRNA vaccine-induced long-term immunity
IL-7 promotes mRNA vaccine-induced long-term immunity
Messenger RNA (mRNA) vaccines are a key technology in combating existing and emerging infectious diseases. However, improv...
Nanotechnology in healthcare, and its safety and environmental risks
Nanotechnology in healthcare, and its safety and environmental risks
Nanotechnology holds immense promise in revolutionising healthcare, offering unprecedented opportunities in diagnostics, d...
Metal-phenolic nanoparticles enhance low temperature photothermal therapy for bacterial biofilm in superficial infections
Metal-phenolic nanoparticles enhance low temperature photothermal therapy for bacterial biofilm in superficial infections
Bacterial infections, especially induced by multidrug-resistant pathogens, have become a significant global health concern...
The role of patient-specific variables in protein corona formation and therapeutic efficacy in nanomedicine
The role of patient-specific variables in protein corona formation and therapeutic efficacy in nanomedicine
Despite their potential, the adoption of nanotechnology in therapeutics remains limited, with only around eighty nanomedic...
Succinate exacerbates mastitis in mice via extracellular vesicles derived from the gut microbiota: a potential new mechanism for mastitis
Succinate exacerbates mastitis in mice via extracellular vesicles derived from the gut microbiota: a potential new mechanism for mastitis
A high grain diet causes an ecological imbalance in the gut microbiota and serves as an important endogenous trigger of ma...
FeS2@COF based nanocarrier for photothermal-enhanced chemodynamic/thermodynamic tumor therapy and immunotherapy via reprograming tumor-associated macrophages
FeS2@COF based nanocarrier for photothermal-enhanced chemodynamic/thermodynamic tumor therapy and immunotherapy via reprograming tumor-associated macrophages
Developing high-performance nanomedicines to enhance antitumor efficacy remains a hot point in the field of biomedicine. I...
Preferential activation of type I interferon-mediated antitumor inflammatory signaling by CuS/MnO2/diAMP nanoparticles enhances anti-PD-1 therapy for sporadic colorectal cancer
Preferential activation of type I interferon-mediated antitumor inflammatory signaling by CuS/MnO2/diAMP nanoparticles enhances anti-PD-1 therapy for sporadic colorectal cancer
Converting the “cold” tumor microenvironment (TME) to a “hot” milieu has become the prevailing app...
Living photosynthetic microneedle patches for in situ oxygenation and postsurgical melanoma therapy
Living photosynthetic microneedle patches for in situ oxygenation and postsurgical melanoma therapy
Surgical excision remains the principal treatment for melanoma, while tumor recurrence and delayed wound healing often occ...
GelMA hydrogels reinforced by PCL@GelMA nanofibers and bioactive glass induce bone regeneration in critical size cranial defects
GelMA hydrogels reinforced by PCL@GelMA nanofibers and bioactive glass induce bone regeneration in critical size cranial defects
The process of bone healing is complex and involves the participation of osteogenic stem cells, extracellular matrix, and ...
Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation
Probiotic-derived extracellular vesicles alleviate AFB1-induced intestinal injury by modulating the gut microbiota and AHR activation
Aflatoxin B1 (AFB1) is a mycotoxin that widely found in the environment and mouldy foods. AFB1 initially targets the intes...
Correction: Conformal immunomodulatory hydrogels for the treatment of otitis media
Correction: Conformal immunomodulatory hydrogels for the treatment of otitis media
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Correction: Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz
Correction: Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
A collagenase-decorated Cu-based nanotheranostics: remodeling extracellular matrix for optimizing cuproptosis and MRI in pancreatic ductal adenocarcinoma
A collagenase-decorated Cu-based nanotheranostics: remodeling extracellular matrix for optimizing cuproptosis and MRI in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC), characterized by a dense extracellular matrix (ECM), presents significant therape...
Silver nanoparticle induced immunogenic cell death can improve immunotherapy
Silver nanoparticle induced immunogenic cell death can improve immunotherapy
Cancer immunotherapy is often hindered by an immunosuppressive tumor microenvironment (TME). Various strategies are being ...
Nanocarriers for intracellular delivery of proteins in biomedical applications: strategies and recent advances
Nanocarriers for intracellular delivery of proteins in biomedical applications: strategies and recent advances
Protein drugs are of great importance in maintaining the normal functioning of living organisms. Indeed, they have been in...
Ion osmolarity-driven sequential concentration-enrichment for the scale-up isolation of extracellular vesicles
Ion osmolarity-driven sequential concentration-enrichment for the scale-up isolation of extracellular vesicles
Extracellular vesicles (EVs) carry a variety of bioactive molecules and are becoming a promising alternative to cell thera...
Binding-driven forward tearing protospacer activated CRISPR-Cas12a system and applications for microRNA detection
Binding-driven forward tearing protospacer activated CRISPR-Cas12a system and applications for microRNA detection
CRISPR-Cas12a system, characterized by its precise sequence recognition and cleavage activity, has emerged as a powerful a...
Manipulation in root-associated microbiome via carbon nanosol for plant growth improvements
Manipulation in root-associated microbiome via carbon nanosol for plant growth improvements
Modulating the microbiome with nanomaterials has been proposed to improve plant growth, and reduce reliance on external in...
A temperature-ultrasound sensitive nanoparticle delivery system for exploring central neuroinflammation mechanism in stroke-heart syndrome
A temperature-ultrasound sensitive nanoparticle delivery system for exploring central neuroinflammation mechanism in stroke-heart syndrome
Cardiovascular events secondary to stroke–collectively classified as stroke-heart syndrome–greatly impair the ...
Organoids and organoid extracellular vesicles-based disease treatment strategies
Organoids and organoid extracellular vesicles-based disease treatment strategies
Organoids are “mini-organs” that self-organize and differentiate from stem cells under in vitro 3D culture con...
Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
Optic nerve regeneration remains challenging worldwide due to the limited intrinsic regenerative capacity of retinal gangl...
Tetrahedral framework nucleic acids inhibit Aβ-mediated ferroptosis and ameliorate cognitive and synaptic impairments in Alzheimer’s disease
Tetrahedral framework nucleic acids inhibit Aβ-mediated ferroptosis and ameliorate cognitive and synaptic impairments in Alzheimer’s disease
Ferroptosis represents a nonapoptotic type of programmed cell death induced by excessive intracellular iron accumulation. ...
A magnetic epitope-imprinted microsphere used for selective separation and rapid detection of SHV-type β-lactamases in bacteria: a novel strategy of antimicrobial resistance detection
A magnetic epitope-imprinted microsphere used for selective separation and rapid detection of SHV-type β-lactamases in bacteria: a novel strategy of antimicrobial resistance detection
The production of β-lactamases is the most prevalent resistance mechanism for β-lactam antibiotics in Gram-negat...
Recent advances of photoresponsive nanomaterials for diagnosis and treatment of acute kidney injury
Recent advances of photoresponsive nanomaterials for diagnosis and treatment of acute kidney injury
Non-invasive imaging in the near-infrared region (NIR) offers enhanced tissue penetration, reduced spontaneous fluorescenc...
IFITM1 is a host restriction factor that inhibits porcine epidemic diarrhea virus infection
IFITM1 is a host restriction factor that inhibits porcine epidemic diarrhea virus infection
Porcine epidemic diarrhea virus (PEDV) infection and transmission pose a serious threat to the global swine industry. The ...
High-throughput synthesis and optimization of ionizable lipids through A3 coupling for efficient mRNA delivery
High-throughput synthesis and optimization of ionizable lipids through A3 coupling for efficient mRNA delivery
The efficacy of mRNA-based vaccines and therapies relies on lipid nanoparticles (LNPs) as carriers to deliver mRNA into ce...
Self-assembly antimicrobial peptide for treatment of multidrug-resistant bacterial infection
Self-assembly antimicrobial peptide for treatment of multidrug-resistant bacterial infection
The wide-spreading of multidrug resistance poses a significant threat to human and animal health. Although antimicrobial p...
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