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Aptamer functionalized nucleic acid nano drug for targeted synergistic therapy for colon cancer
Aptamer functionalized nucleic acid nano drug for targeted synergistic therapy for colon cancer
Due to its complicated pathophysiology, propensity for metastasis, and poor prognosis, colon cancer is challenging to trea...
Correction: Acidic and hypoxic tumor microenvironment regulation by CaO2-loaded polydopamine nanoparticles
Correction: Acidic and hypoxic tumor microenvironment regulation by CaO2-loaded polydopamine nanoparticles
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Biomedical application of 2D nanomaterials in neuroscience
Biomedical application of 2D nanomaterials in neuroscience
Two-dimensional (2D) nanomaterials, such as graphene, black phosphorus and transition metal dichalcogenides, have attracte...
Correction: NIR-II-absorbing diimmonium polymer agent achieves excellent photothermal therapy with induction of tumor immunogenic cell death
Correction: NIR-II-absorbing diimmonium polymer agent achieves excellent photothermal therapy with induction of tumor immunogenic cell death
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Yunnan Baiyao-loaded multifunctional microneedle patches for rapid hemostasis and cutaneous wound healing
Yunnan Baiyao-loaded multifunctional microneedle patches for rapid hemostasis and cutaneous wound healing
Microneedle patches have been extensively employed for wound healing, while the lack of rapid hemostasis efficiency and mu...
Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair
Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair
Angiogenesis and tissue repair in chronic non-healing diabetic wounds remain critical clinical problems. Engineered MSC-de...
A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching
A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching
Congenital disorders of glycosylation (CDGs) are genetic diseases caused by gene defects in glycan biosynthesis pathways, ...
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy
Long-term chronic inflammation after Achilles tendon injury is critical for tendinopathy. Platelet-rich plasma (PRP) injec...
A novel ROS-Related chemiluminescent semiconducting polymer nanoplatform for acute pancreatitis early diagnosis and severity assessment
A novel ROS-Related chemiluminescent semiconducting polymer nanoplatform for acute pancreatitis early diagnosis and severity assessment
Acute pancreatitis (AP) is a common and potentially life-threatening inflammatory disease of the pancreas. Reactive oxygen...
A bifunctional bortezomib-loaded porous nano-hydroxyapatite/alginate scaffold for simultaneous tumor inhibition and bone regeneration
A bifunctional bortezomib-loaded porous nano-hydroxyapatite/alginate scaffold for simultaneous tumor inhibition and bone regeneration
Treatments of osteolytic lesions due to malignant metastasis remain one of the major clinical challenges. The residual tum...
Softness enhanced macrophage-mediated therapy of inhaled apoptotic-cell-inspired nanosystems for acute lung injury
Softness enhanced macrophage-mediated therapy of inhaled apoptotic-cell-inspired nanosystems for acute lung injury
Engineered nanosystems offer a promising strategy for macrophage-targeted therapies for various diseases, and their physic...
Titanium biogenic nanoparticles to help the growth of Trichoderma harzianum to be used in biological control
Titanium biogenic nanoparticles to help the growth of Trichoderma harzianum to be used in biological control
The biogenic synthesis of metallic nanoparticles is a green alternative that reduces the toxicity of this nanomaterials an...
Tumor microenvironment-responsive spherical nucleic acid nanoparticles for enhanced chemo-immunotherapy
Tumor microenvironment-responsive spherical nucleic acid nanoparticles for enhanced chemo-immunotherapy
Certain chemotherapeutics can induce tumor cells’ immunogenic cell death (ICD), release tumor antigens, and thereby ...
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator
Periplaneta americana L. derived exosome-like nanoparticles (PA-ELNs) as a novel wound healing accelerator was isolated an...
Bioengineered stem cell membrane functionalized nanoparticles combine anti-inflammatory and antimicrobial properties for sepsis treatment
Bioengineered stem cell membrane functionalized nanoparticles combine anti-inflammatory and antimicrobial properties for sepsis treatment
Sepsis is a syndrome of physiological, pathological and biochemical abnormalities caused by infection. Although the mortal...
A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation
A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation
Ankylosing spondylitis (AS) is a common rheumatic disorder distinguished by chronic inflammation and heterotopic ossificat...
A hybrid nanopharmaceutical for specific-amplifying oxidative stress to initiate a cascade of catalytic therapy for pancreatic cancer
A hybrid nanopharmaceutical for specific-amplifying oxidative stress to initiate a cascade of catalytic therapy for pancreatic cancer
Oxidative stress (OS) induced by an imbalance of oxidants and antioxidants is an important aspect in anticancer therapy, h...
Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles, universally exist in body flui...
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis
Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis
Plant-derived exosomes-like nanovesicles (PDENs) have been found to be advantageous in disease treatment and drug delivery...
CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
Combinatorial immunotherapy strategies for enhancing the responsiveness of immune system have shown great promise for canc...
Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair
Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair
Large-scale skin damage brings potential risk to patients, such as imbalance of skin homeostasis, inflammation, fluid loss...
Role of bioactive magnetic nanoparticles in the prevention of wound pathogenic biofilm formation using smart nanocomposites
Role of bioactive magnetic nanoparticles in the prevention of wound pathogenic biofilm formation using smart nanocomposites
Biofilm formation and its resistance to various antibiotics is a serious health problem in the treatment of wound infectio...
Zn-MOF hydrogel: regulation of ROS-mediated inflammatory microenvironment for treatment of atopic dermatitis
Zn-MOF hydrogel: regulation of ROS-mediated inflammatory microenvironment for treatment of atopic dermatitis
Atopic dermatitis (AD) is a chronic and recurrent inflammation disease associated with immune dysfunction. The high level ...
Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies
Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies
Surgical resection is the cornerstone of solid tumour treatment. Current techniques for evaluating margin statuses, such a...
Engineered extracellular vesicles mediated CRISPR-induced deficiency of IQGAP1/FOXM1 reverses sorafenib resistance in HCC by suppressing cancer stem cells
Engineered extracellular vesicles mediated CRISPR-induced deficiency of IQGAP1/FOXM1 reverses sorafenib resistance in HCC by suppressing cancer stem cells
Sorafenib resistance poses therapeutic challenges in HCC treatment, in which cancer stem cells (CSCs) plays a crucial role...
Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy
Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy
PCSK9, which is closely related to atherosclerosis, is significantly expressed in vascular smooth muscle cells (VSMCs). Mo...
Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2
Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2
The development of vaccines based on outer membrane vesicles (OMV) that naturally bud off from bacteria is an evolving fie...
Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility
Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility
Extracellular vesicles (EV) are extensively studied in human body fluids as potential biomarkers for numerous diseases. Ma...
Metabolomic investigation of urinary extracellular vesicles for early detection and screening of lung cancer
Metabolomic investigation of urinary extracellular vesicles for early detection and screening of lung cancer
Lung cancer is a prevalent cancer type worldwide that often remains asymptomatic in its early stages and is frequently dia...
Mild photothermal/radiation therapy potentiates ferroptosis effect for ablation of breast cancer via MRI/PA imaging guided all-in-one strategy
Mild photothermal/radiation therapy potentiates ferroptosis effect for ablation of breast cancer via MRI/PA imaging guided all-in-one strategy
Nanotheranostics advances anticancer management by providing therapeutic and diagnostic functions, that combine programmed...
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