Advances in Pharmacology and Pharmacy Vol. 12(4), pp. 338 - 350
DOI: 10.13189/app.2024.120406
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Keshavnam M. Chitte 1, Disha Prajapati 2,*, Tanvi Dodiya 2, Janvi Patel 1, Rishikesh Wagh 1
1 Department of Quality Assurance, Parul Institute of Pharmacy & Research, Parul University Limda, India
2 Department of Pharmacognosy, Parul Institute of Pharmacy & Research, Parul University Limda, India

ABSTRACT

The present review aims to compile various pharmacological activities, extraction techniques, and analytical techniques for Bergenin. Bergenin, a polyphenol compound that is a C-glycoside of 4-O-methyl gallic acid, has been discovered naturally via several different species, such as Bergenia ciliata, Mallotus Philippines, Bergenia ligulata, Rivea ornata roxb, Bergenia Strachey, Flueggea virosa, Caesalpinia digyna Rottler, Actaea acuminata, Mallotus repandus Muell, etc. Various online search engines like Google Scholar, PUBMED, the National Center for Biotechnology Information, MedlinePlus and Herbal Medicine were used for data mining of published research work. A comprehensive review was compiled, considering the various aspects related to Bergenin. Bergenin exhibits many pharmacological activities, including the ability to stop arrhythmia, HIV, anxiety, fungal infections, viruses, fungal infections, cancer, inflammation, and bacteria. Various methods are available for the extraction of bergenin from various plant species. The profoundly used extraction methods include soxhlet extraction and maceration using methanol as the solvent. The pharmacological actions, investigative methodologies, and extraction methods utilized for identifying and quantifying bergenin and its combinations are covered in detail in the current review. Bergenin can be identified and quantified using various analytical methods such as HPTLC, HPLC, HPLC-MS, LC-MS/MS, LC-MS, UPLC-PDA, and UHPLC-MS. The information compiled in the present review will guide the exploration and selection of analytical methods for evaluating bergenin in plant species, herbal, and ayurvedic formulations.

KEYWORDS
Bergenin, Pharmacology, Extraction, HPTLC, HPLC

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Keshavnam M. Chitte , Disha Prajapati , Tanvi Dodiya , Janvi Patel , Rishikesh Wagh , "Review on Pharmacological Activities, Extraction and Analytical Techniques of Bergenin," Advances in Pharmacology and Pharmacy, Vol. 12, No. 4, pp. 338 - 350, 2024. DOI: 10.13189/app.2024.120406.

(b). APA Format:
Keshavnam M. Chitte , Disha Prajapati , Tanvi Dodiya , Janvi Patel , Rishikesh Wagh (2024). Review on Pharmacological Activities, Extraction and Analytical Techniques of Bergenin. Advances in Pharmacology and Pharmacy, 12(4), 338 - 350. DOI: 10.13189/app.2024.120406.