Advances in Pharmacology and Pharmacy Vol. 12(4), pp. 298 - 312
DOI: 10.13189/app.2024.120403
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Aarti Tiwari , Kiran Patel , Pradeep Kumar Samal *
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, India

ABSTRACT

Rheumatoid arthritis, often known as RA, is an autoimmune disorder that has a pathophysiology that is not completely understood. There are a broad variety of elements that may have an effect on its etiology, including environmental factors, genetic factors, microbes, medicines, and hormones. Additionally, it has a substantial influence on the lives of a large number of people. In the majority of instances, DMARDs are the drugs that are used the most often for the treatment and modification of ailments that are associated with rheumatoid arthritis (RA). Nevertheless, there are a great many herbs that might be the subject of study for the modification of diseases associated to rheumatoid arthritis by researchers. We developed our research study in which we generated rheumatoid arthritis (RA) in rats in order to take advantage of the restricted usage of capsaicin in the treatment of rheumatoid arthritis (RA). After that, we investigated the effects of capsaicin on its own and in conjunction with the phosphatidylcholine (PC) complex, and we analyzed the activity of both of these substances. When we compared our findings with those of the illness group, we found that the combination of capsaicin and PC complex had the potential to alter the outcomes that were seen in our experiment. Following the completion of our trials, we arrived to the conclusion that the combination of capsaicin and PC has the potential to play a significant role in the treatment of rheumatoid arthritis (RA).

KEYWORDS
Rheumatoid Arthritis, Phosphatidylcholine, DMARDs, Capsaicin

Cite This Paper in IEEE or APA Citation Styles
(a). IEEE Format:
[1] Aarti Tiwari , Kiran Patel , Pradeep Kumar Samal , "Oral Bioefficacy Enhancement of Capsaicin for the Effective Treatment of Rheumatoid Arthritis," Advances in Pharmacology and Pharmacy, Vol. 12, No. 4, pp. 298 - 312, 2024. DOI: 10.13189/app.2024.120403.

(b). APA Format:
Aarti Tiwari , Kiran Patel , Pradeep Kumar Samal (2024). Oral Bioefficacy Enhancement of Capsaicin for the Effective Treatment of Rheumatoid Arthritis. Advances in Pharmacology and Pharmacy, 12(4), 298 - 312. DOI: 10.13189/app.2024.120403.