An J, An S, Choi M, Jung JH, Kim B (2022) Natural products for esophageal cancer therapy: from traditional medicine to modern drug discovery. Int J Mol Sci 23:13558. https://doi.org/10.3390/ijms232113558
Article CAS PubMed PubMed Central Google Scholar
Arnold M, Ferlay J, Van Berge Henegouwen MI, Soerjomataram I (2020) Global burden of oesophageal and gastric cancer by histology and subsite in 2018. Gut 69:1564–1571. https://doi.org/10.1136/gutjnl-2020-321600
Bansal A, Celeste Simon M (2018) Glutathione metabolism in cancer progression and treatment resistance. J Cell Biol 217:2291–2298. https://doi.org/10.1083/jcb.201804161
Article CAS PubMed PubMed Central Google Scholar
Blank S, Nienhüser H, Dreikhausen L, Sisic L, Heger U, Ott K, Schmidt T (2017) Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer. Oncotarget 8:47518–47532. https://doi.org/10.18632/oncotarget.17671
Article PubMed PubMed Central Google Scholar
Brand TM, Iida M, Luthar N, Starr MM, Huppert EJ, Wheeler DL (2013) Nuclear EGFR as a molecular target in cancer. Radiother Oncol 108:370–377. https://doi.org/10.1016/j.radonc.2013.06.010
Article CAS PubMed Google Scholar
Carneiro BA, El-Deiry WS (2020) Targeting apoptosis in cancer therapy. Nat Rev Clin Oncol 17:395–417. https://doi.org/10.1038/s41571-020-0341-y
Article PubMed PubMed Central Google Scholar
Chae JB, Kim JS, Choi ST, Lee SG, Ojulari OV, Kang YJ, Kwon TK, Nam J-O (2021) Farrerol induces cancer cell death via ERK activation in SKOV3 cells and attenuates TNF-α-mediated lipolysis. Int J Mol Sci 22:9400. https://doi.org/10.3390/ijms22179400
Article CAS PubMed PubMed Central Google Scholar
Chen R, Zheng R, Zhang S, Wang S, Sun K, Zeng H, Li L, Wei W, He J (2023) Patterns and trends in esophageal cancer incidence and mortality in China: an analysis based on cancer registry data. J Natl Cancer Cent 25:21–27. https://doi.org/10.1016/j.jncc.2023.01.002
Cui B, Zhang S, Wang Y, Guo Y (2019) Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line. Biomed Pharmacother 109:112–119. https://doi.org/10.1016/j.biopha.2018.10.053
Article CAS PubMed Google Scholar
Evan GI, Vousden KH (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411:342–348. https://doi.org/10.1038/35077213
Article CAS PubMed Google Scholar
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57–70. https://doi.org/10.1007/s00262-010-0968-0
Article CAS PubMed Google Scholar
Hoshino A, Ariyoshi M, Okawa Y, Matoba S (2014) Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes. Proc Natl Acad Sci U S A 111:3116–3121. https://doi.org/10.1073/pnas.1318951111
Article CAS PubMed PubMed Central Google Scholar
Huang S, Guo Y, Li Z, Zhang Y, Zhou T, You W, Pan K, Li W (2020) A systematic review of metabolomic profiling of gastric cancer and esophageal cancer. Cancer Biol Med 17:181–198. https://doi.org/10.20892/j.issn.2095-3941.2019.0348
Article CAS PubMed PubMed Central Google Scholar
Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432:316–23. https://doi.org/10.1038/nature03097
Article CAS PubMed Google Scholar
Katz L, Baltz RH (2016) Natural product discovery: past, present, and future. J Ind Microbiol Biotechnol 43:155–176. https://doi.org/10.1007/s10295-015-1723-5
Article CAS PubMed Google Scholar
Khan AQ, Rashid K, AlAmodi AA, Agha MV, Akhtar S, Hakeem I, Raza SS, Uddin S (2021) Reactive oxygen species (ROS) in cancer pathogenesis and therapy: an update on the role of ROS in anticancer action of benzophenanthridine alkaloids. Biomed Pharmacother 143:112142. https://doi.org/10.1016/j.biopha.2021.112142
Article CAS PubMed Google Scholar
Lee HJ, Zhuang G, Cao Y, Du P, Kim HJ, Settleman J (2014) Drug resistance via feedback activation of stat3 in oncogene-addicted cancer cells. Cancer Cell 26:207–221. https://doi.org/10.1016/j.ccr.2014.05.019
Article CAS PubMed Google Scholar
Liu J, Wang H, Wang Y, Yin Y, Du Z, Liu Z, Yang J, Hu S, Wang C, Chen Y (2014) The stem cell adjuvant with Exendin-4 repairs the heart after myocardial infarction via STAT3 activation. J Cell Mol Med 18:1381–1391. https://doi.org/10.1111/jcmm.12272
Article CAS PubMed PubMed Central Google Scholar
Liu E, Liang T, Wang X, Ban S, Han L, Li Q (2015) Apoptosis induced by farrerol in human gastric cancer SGC-7901 cells through the mitochondrial-mediated pathway. Eur J Cancer Prev 24:365–372. https://doi.org/10.1097/CEJ.0000000000000104
Article CAS PubMed Google Scholar
Luo Y, Cobb RE, Zhao H (2014) Recent advances in natural product discovery. Curr Opin Biotechnol 30:230–237. https://doi.org/10.1016/j.copbio.2014.09.002
Article CAS PubMed Google Scholar
Ma N, Wei W, Fan X, Ci X (2019) Farrerol attenuates cisplatin-induced nephrotoxicity by inhibiting the reactive oxygen species-mediated oxidation, inflammation, and apoptotic signaling pathways. Front Physiol 10:1419. https://doi.org/10.3389/fphys.2019.01419
Article PubMed PubMed Central Google Scholar
Morgan E, Soerjomataram I, Rumgay H, Coleman HG, Thrift AP, Vignat J, Laversanne M, Ferlay J, Arnold M (2022) The global landscape of esophageal squamous cell carcinoma and esophageal adenocarcinoma incidence and mortality in 2020 and projections to 2040: new estimates from GLOBOCAN 2020. Gastroenterology 163:649–658. https://doi.org/10.1053/j.gastro.2022.05.054
Nicholson RI, Gee JMW, Harper ME (2001) EGFR and cancer prognosis. Eur J Cancer 37(Suppl 4):S9-15. https://doi.org/10.1016/s0959-8049(01)00231-3
Article CAS PubMed Google Scholar
Ooki A, Osumi H, Chin K, Watanabe M, Yamaguchi K. (2023) Potent molecular-targeted therapies for advanced esophageal squamous cell carcinoma. Ther Adv Med Oncol 15. https://doi.org/10.1177/17588359221138377
Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, Castoria G, Migliaccio A (2020) ROS in cancer therapy: the bright side of the moon. Exp Mol Med 52:192–203. https://doi.org/10.1038/s12276-020-0384-2
Article CAS PubMed PubMed Central Google Scholar
Ponte LG, Pavan IC, Mancini MC, da Silva LG, Morelli AP, Severino MB, Bezerra RM, Simabuco FM (2021) The hallmarks of flavonoids in cancer. Molecules 26:2029. https://doi.org/10.3390/molecules26072029
Article CAS PubMed PubMed Central Google Scholar
Qin X, Xu X, Hou X, Liang R, Chen L, Hao Y, Gao A, Du X, Zhao L, Shi Y, Li Q (2022) The pharmacological properties and corresponding mechanisms of farrerol: a comprehensive review. Pharm Biol 60:9–16. https://doi.org/10.1080/13880209.2021.2006723
Article CAS PubMed Google Scholar
Ran X, Li Y, Chen G, Fu S, He D, Huang B, Wei L, Lin Y, Guo Y, Hu G (2018) Farrerol ameliorates TNBS-induced colonic inflammation by inhibiting ERK1/2, JNK1/2, and NF-κB signaling pathway. Int J Mol Sci 19:2037. https://doi.org/10.3390/ijms19072037
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