Yamakawa N, Suemasu S, Matoyama M, Tanaka K-I, Katsu T, Miyata K, Okamoto Y, Otsuka M, Mizushima T. Synthesis and biological evaluation of loxoprofen derivatives. Bioorg Med Chem. 2011;19:3299–311. https://doi.org/10.1016/j.bmc.2011.04.050.
Article CAS PubMed Google Scholar
Greig SL, Garnock-Jones KP. Loxoprofen: a review in pain and inflammation. Clin Drug Investig. 2016;36:771–81. https://doi.org/10.1007/s40261-016-0440-9.
Article CAS PubMed Google Scholar
Ohara H, Miyabe Y, Deyashiki Y, Matsuura K, Kara A. Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver. Biochem Pharmacol. 1995;50:221–7. https://doi.org/10.1016/0006-2952(95)00124-I.
Article CAS PubMed Google Scholar
Arakawa T, Fujiwara Y, Sollano JD, Zhu Q, Kachintorn U, Rani AA, Hahm K-B, Takahashi S-I, Joh T, Kinoshita Y. A questionnaire-based survey on the prescription of non-steroidal anti-inflammatory drugs by physicians in East Asian countries in 2007. Digestion. 2009;79:177–85. https://doi.org/10.1159/000211713.
Mu R, Bao C-D, Chen Z-W, Zheng Y, Wang G-C, Zhao D-B, Hu S-X, Li Y-J, Shao Z-W, Zhang Z-Y. Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial. Clin Rheumatol. 2016;35:165–73. https://doi.org/10.1007/s10067-014-2701-4.
Sekiguchi H, Inoue G, Nakazawa T, Imura T, Saito W, Uchida K, Miyagi M, Takahira N, Takaso M. Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study. J Orthop Sci. 2015;20:617–23. https://doi.org/10.1007/s00776-015-0726-4.
Article CAS PubMed Google Scholar
Miki K, Ikemoto T, Hayashi K, Arai Y-C, Sekiguchi M, Shi K, Ushida T. Randomized open-labbel non-inferiority trial of acetaminophen or loxoprofen for patients with acute low back pain. J Orthop Sci. 2018;23:483–7. https://doi.org/10.1016/j.jos.2018.02.007.
Li D, Cheng Y, Yuan P, Wu Z, Liu J, Kan J, Zhang K, Wang Z, Zhang H, Zhang G. Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis: a randomized controlled trial. Chin Med J. 2023;136:2187–94. https://doi.org/10.1097/CM9.0000000000002797.
Article CAS PubMed PubMed Central Google Scholar
Ohta S, Komai O, Hanakawa H. Comparative study of the clinical efficacy of the selective cyclooxygenase-2 inhibitor celecoxib compared with loxoprofen in patients with frozen shoulder. Mod Rheumatol. 2014;24:144–9. https://doi.org/10.3109/14397595.2013.852857.
Article CAS PubMed Google Scholar
Jang J-H, Jeong S-H, Lee Y-B. Population pharmacokinetic modeling of zaltoprofen in healthy adults: exploring the dosage regimen. Pharmaceuticals. 2023;16:161. https://doi.org/10.3390/ph16020161.
Article CAS PubMed PubMed Central Google Scholar
Jeong S-H, Jang J-H, Lee Y-B. Modeling population pharmacokinetics of morniflumate in healthy Korean men: extending pharmacometrics analysis to niflumic acid, its major active metabolite. Naunyn-Schmiedeberg’s Arch Pharmacol. 2024;397:843–56. https://doi.org/10.1007/s00210-023-02640-0.
Kashif M, Rahman N-U, Idrees HA, Aslam I, Iqbal SM, Mustafa R. HPLC-UV detection method for quantification of loxoprofen in human plasma with liquid-liquid extraction technique: application in pharmacokinetic study. Lat Am J Pharm. 2013;32:587–92.
Helmy SA. Pharmacokinetics and bioequivalence evaluation of 2 loxoprofen tablets in healthy egyptian male volunteers. Clin Pharmacol Drug Dev. 2013;2:173–7. https://doi.org/10.1002/cpdd.15.
Article CAS PubMed Google Scholar
Loya P, Kshatriya AA, Saraf MN. Bioequivalence study of two brands of loxoprofen tablets in healthy volunteers. Int J PharmTech Res. 2011;3:2038–46.
Kang H-A, Cho H-Y, Lee Y-B. Bioequivalence of hana loxoprofen sodium tablet to dongwha Loxonin® tablet (Loxoprofen Sodium 60 mg). J Pharm Investig. 2011;41:117–23. https://doi.org/10.4333/KPS.2011.41.2.117.
Lee HW, Ji HY, Sohn DH, Kim SM, Lee YB, Lee HS. Liquid chromatography–tandem mass spectrometry method of loxoprofen in human plasma. Biomed Chromatogr. 2009;23:714–8. https://doi.org/10.1002/bmc.1175.
Article CAS PubMed Google Scholar
Jhee OH, Lee MH, Shaw LM, Lee SE, Park JH, Kang JS. Pharmacokinetics and bioequivalence study of two brands of loxoprofen tablets in healthy volunteers. Arzneimittelforschung. 2007;57:542–6. https://doi.org/10.1055/s-0031-1296646.
Article CAS PubMed Google Scholar
Hao L, Sun J-G, Wang G-J, Jiang X-L, Xie Y-Y, Li P. Rapid determination of loxoprofen in human plasma by HPLC-MS and its pharmacokinetics and bioequivalence study. Chin J Clin Pharmacol Ther. 2006;11:211.
Cho H-Y, Park C-H, Lee Y-B. Direct and simultaneous analysis of loxoprofen and its diastereometric alcohol metabolites in human serum by on-line column switching liquid chromatography and its application to a pharmacokinetic study. J Chromatogr B. 2006;835:27–34. https://doi.org/10.1016/j.jchromb.2006.02.058.
Kim I-W, Chung S-J, Shim C-K. Altered metabolism of orally administered loxoprofen in human subjects after an oral administration of loxoprofen for three consecutive days followed by a seven-day washout. J Pharm Sci. 2002;91:973–9. https://doi.org/10.1002/jps.10040.
Article CAS PubMed Google Scholar
Choo K-S, Kim I-W, Jung J-K, Suh Y-G, Chung S-J, Lee M-H, Shim C-K. Simultaneous determination of loxoprofen and its diastereomeric alcohol metabolites in human plasma and urine by a simple HPLC-UV detection method. J Pharm Biomed Anal. 2001;25:639–50. https://doi.org/10.1016/S0731-7085(00)00583-5.
Article CAS PubMed Google Scholar
Kim I-W, Han T-G, Kim K-S, Chung S-J, Lee M-H, Shim C-K. Bioequivalence of loxipen tablet to loxonin tablet (sodium loxoprofen anhydride 60 mg). J Pharm Investig. 1998;28:185–91.
Kim S-J, Oh I-J, Shin S-C, Lee Y-B, Joh H-N, Suh S-P. Bioequivalence of loxoprofen tablets. Korean J Clin Pharm. 1997;7:73–80.
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