Richette P, Bardin T. Gout. Lancet. 2010;375(9711):318–28.

Article  PubMed  CAS  Google Scholar 

Bursill D, Taylor WJ, Terkeltaub R, Abhishek A, So AK, Vargas-Santos AB, et al. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout. Ann Rheum Dis. 2019;78(11):1592–600.

Article  PubMed  Google Scholar 

FitzGerald JD, Dalbeth N, Mikuls T, Brignardello-Petersen R, Guyatt G, Abeles AM, et al. 2020 American College of Rheumatology guideline for the management of Gout. Arthritis Rheumatol. 2020;72(6):879–95.

Article  PubMed  Google Scholar 

Mandl P, D’Agostino MA, Navarro-Compan V, Gessl I, Sakellariou G, Abhishek A, et al. 2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice. Ann Rheum Dis. 2024;83(6):752–9.

Article  PubMed  Google Scholar 

Pascart T, Budzik JF. Dual-energy computed tomography in crystalline arthritis: knowns and unknowns. Curr Opin Rheumatol. 2022;34(2):103–10.

Article  PubMed  Google Scholar 

Richette P, Doherty M, Pascual E, Barskova V, Becce F, Castaneda J, et al. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann Rheum Dis. 2020;79(1):31–8.

Article  PubMed  Google Scholar 

Leask MP, Merriman TR. The genetic basis of urate control and gout: Insights into molecular pathogenesis from follow-up study of genome-wide association study loci. Best Pract Res Clin Rheumatol. 2021;35(4): 101721.

Article  PubMed  Google Scholar 

Kuo CF, Grainge MJ, Zhang W, Doherty M. Global epidemiology of gout: prevalence, incidence and risk factors. Nat Rev Rheumatol. 2015;11(11):649–62.

Article  PubMed  Google Scholar 

Chen-Xu M, Yokose C, Rai SK, Pillinger MH, Choi HK. Contemporary prevalence of gout and hyperuricemia in the United States and decadal trends: the National Health and Nutrition Examination Survey, 2007–2016. Arthritis Rheumatol. 2019;71(6):991–9.

Article  PubMed  PubMed Central  Google Scholar 

Bardin T, Bouee S, Clerson P, Chales G, Flipo RM, Liote F, et al. Prevalence of Gout in the adult population of France. Arthritis Care Res (Hoboken). 2016;68(2):261–6.

Article  PubMed  Google Scholar 

Bardin T, Magnat E, Clerson P, Richette P, Rouchon B. Epidemiology of gout and hyperuricemia in New Caledonia. Joint Bone Spine. 2022;89(2): 105286.

Article  PubMed  CAS  Google Scholar 

Klemp P, Stansfield SA, Castle B, Robertson MC. Gout is on the increase in New Zealand. Ann Rheum Dis. 1997;56(1):22–6.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pascart T, Wasik KA, Preda C, Chune V, Torterat J, Prud’homme N, et al. The gout epidemic in French Polynesia: a modelling study of data from the Ma’i u’u epidemiological survey. Lancet Glob Health. 2024;12(4):e685–96.

Article  PubMed  CAS  Google Scholar 

Xia Y, Wu Q, Wang H, Zhang S, Jiang Y, Gong T, et al. Global, regional and national burden of gout, 1990–2017: a systematic analysis of the Global Burden of Disease Study. Rheumatology (Oxford). 2020;59(7):1529–38.

Article  PubMed  CAS  Google Scholar 

Choi HK, Ford ES, Li C, Curhan G. Prevalence of the metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination Survey. Arthritis Rheum. 2007;57(1):109–15.

Article  PubMed  Google Scholar 

Grundy SM, Brewer HB Jr, Cleeman JI, Smith SC Jr, Lenfant C, American Heart A, et al. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation. 2004;109(3):433–8.

Article  PubMed  Google Scholar 

Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al. Heart disease and stroke statistics-2017 update: a report from the American Heart Association. Circulation. 2017;135(10):e146–603.

Article  PubMed  PubMed Central  Google Scholar 

Hirode G, Wong RJ. Trends in the prevalence of metabolic syndrome in the United States, 2011–2016. JAMA. 2020;323(24):2526–8.

Article  PubMed  PubMed Central  Google Scholar 

Wiley JF, Carrington MJ. A metabolic syndrome severity score: a tool to quantify cardio-metabolic risk factors. Prev Med. 2016;88:189–95.

Article  PubMed  Google Scholar 

Jung JH, Song GG, Ji JD, Lee YH, Kim JH, Seo YH, et al. Metabolic syndrome: prevalence and risk factors in Korean gout patients. Korean J Intern Med. 2018;33(4):815–22.

Article  PubMed  Google Scholar 

Schlesinger N, Elsaid MI, Rustgi VK. The relationship between metabolic syndrome severity and the risk of mortality in gout patients: a population-based study. Clin Exp Rheumatol. 2022;40(3):631–3.

Article  PubMed  Google Scholar 

Andres M. Gout and Cardiovascular Disease: Mechanisms, Risk Estimations, and the Impact of Therapies. Gout Urate Cryst Depos Dis. 2023;1(3):152–66.

Article  Google Scholar 

Choi HK, Curhan G. Independent impact of gout on mortality and risk for coronary heart disease. Circulation. 2007;116(8):894–900.

Article  PubMed  Google Scholar 

Ferguson LD, Molenberghs G, Verbeke G, Rahimi K, Rao S, McInnes IB, et al. Gout and incidence of 12 cardiovascular diseases: a case-control study including 152 663 individuals with gout and 709 981 matched controls. Lancet Rheumatol. 2024;6(3):e156–67.

Article  PubMed  CAS  Google Scholar 

Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med. 2004;350(11):1093–103.

Article  PubMed  CAS  Google Scholar 

Choi HK, De Vera MA, Krishnan E. Gout and the risk of type 2 diabetes among men with a high cardiovascular risk profile. Rheumatology (Oxford). 2008;47(10):1567–70.

Article  PubMed  CAS  Google Scholar 

Pan A, Teng GG, Yuan JM, Koh WP. Bidirectional association between self-reported hypertension and gout: the Singapore Chinese health study. PLoS One. 2015;10(10): e0141749.

Article  PubMed  PubMed Central  Google Scholar 

Clarson LE, Chandratre P, Hider SL, Belcher J, Heneghan C, Roddy E, et al. Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. Eur J Prev Cardiol. 2015;22(3):335–43.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Perez-Ruiz F, Martinez-Indart L, Carmona L, Herrero-Beites AM, Pijoan JI, Krishnan E. Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout. Ann Rheum Dis. 2014;73(1):177–82.

Article  PubMed  CAS  Google Scholar 

Clarson LE, Hider SL, Belcher J, Heneghan C, Roddy E, Mallen CD. Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Ann Rheum Dis. 2015;74(4):642–7.

Article  PubMed  Google Scholar 

Kuo CF, Grainge MJ, Mallen C, Zhang W, Doherty M. Comorbidities in patients with gout prior to and following diagnosis: case-control study. Ann Rheum Dis. 2016;75(1):210–7.

Article  PubMed  Google Scholar 

Choi HK, McCormick N, Yokose C. Excess comorbidities in gout: the causal paradigm and pleiotropic approaches to care. Nat Rev Rheumatol. 2022;18(2):97–111.

Article  PubMed  Google Scholar 

Borghi C, Agabiti-Rosei E, Johnson RJ, Kielstein JT, Lurbe E, Mancia G, et al. Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease. E