Lange M, Hardy-Léger I, Licaj I, Pistilli B, Rigal O, Le Fel J, et al. Cognitive impairment in patients with breast cancer before surgery: results from a CANTO cohort subgroup. Cancer Epidemiol Biomark Prev. 2020;29:1759–66.

Article  Google Scholar 

Lange M, Lefevre Arbogast S, Hardy-Léger I, Rigal O, Le Fel J, Pistilli B, et al. Cognitive change in breast cancer patients up to 2 years after diagnosis. JNCI J Natl Cancer Inst. 2023;115:322–31.

Article  PubMed  Google Scholar 

Castel H, Denouel A, Lange M, Tonon M-C, Dubois M, Joly F. Biomarkers associated with cognitive impairment in treated cancer patients: potential predisposition and risk factors. Front Pharmacol. 2017;8:1–19.

Article  Google Scholar 

Sleurs C, Amidi A, Wu LM, Kiesl D, Zimmer P, Lange M, et al. Cancer-related cognitive impairment in non-CNS cancer patients: targeted review and future action plans in Europe. Crit Rev Oncol Hematol. 2022;180:103859.

Article  PubMed  Google Scholar 

Schroyen G, Vissers J, Smeets A, Gillebert CR, Lemiere J, Sunaert S, et al. Blood and neuroimaging biomarkers of cognitive sequelae in breast cancer patients throughout chemotherapy: a systematic review. Transl Oncol. 2022;16:101297.

Article  CAS  PubMed  Google Scholar 

Caselli RJ, Dueck AC, Osborne D, Sabbagh MN, Connor DJ, Ahern GL, et al. Longitudinal modeling of age-related memory decline and the APOE ε4 effect. N Engl J Med. 2009;361:255–63.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao N, Ren Y, Yamazaki Y, Qiao W, Li F, Felton LM, et al. Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways. Neuron. 2020;106:727-742.e6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Flowers SA, Rebeck GW. APOE in the normal brain. Neurobiol Dis. 2020;136:104724.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koleck TA, Bender CM, Sereika SM, Ahrendt G, Jankowitz RC, McGuire KP, et al. Apolipoprotein E genotype and cognitive function in postmenopausal women with early-stage breast cancer. Oncol Nurs Forum. 2014;41:E313–25.

Article  PubMed  PubMed Central  Google Scholar 

Ahles TA, Saykin AJ, Noll WW, Furstenberg CT, Guerin S, Cole B, et al. The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy. Psychooncology. 2003;12:612–9.

Article  PubMed  Google Scholar 

Buskbjerg CDR, Amidi A, Demontis D, Nissen ER, Zachariae R. Genetic risk factors for cancer-related cognitive impairment: a systematic review. Acta Oncol. 2019;58:537–47.

Article  CAS  PubMed  Google Scholar 

Ahles TA, Orlow I, Schofield E, Li Y, Ryan E, Root JC, et al. The impact of APOE and smoking history on cognitive function in older, long-term breast cancer survivors. J Cancer Surviv. 2022. https://doi.org/10.1007/s11764-022-01267-z.

Article  PubMed  PubMed Central  Google Scholar 

Ahles TA, McDonald BC, Schwartz GN, Kaufman PA, Tsongalis GJJ, Moore JHH, et al. Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: the impact of APOE and smoking. Psychooncology. 2014;23:1382–90.

Article  PubMed  PubMed Central  Google Scholar 

Amidi A, Agerbæk M, Wu LM, Pedersen AD, Mehlsen M, Clausen CR, et al. Changes in cognitive functions and cerebral grey matter and their associations with inflammatory markers, endocrine markers, and APOE genotypes in testicular cancer patients undergoing treatment. Brain Imaging Behav. 2017;11:769–83.

Article  PubMed  Google Scholar 

Van Dyk K, Crespi CM, Bower JE, Carroll JE, Petersen L, Ganz PA. Association of APOE4 genotype and treatment with cognitive outcomes in breast cancer survivors over time. npj Breast Cancer. 2021;7:6–9.

Google Scholar 

Pontifex MG, Martinsen A, Saleh RNM, Harden G, Tejera N, Müller M, et al. APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE-TR mice. FASEB J. 2021. https://doi.org/10.1096/fj.202002621RR.

Article  PubMed  Google Scholar 

Wefel JS, Vardy J, Ahles T, Schagen SB. International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer. Lancet Oncol. 2011;12:703–8.

Article  PubMed  Google Scholar 

Mulholland MM, Prinsloo S, Kvale E, Dula AN, Palesh O, Kesler SR. Behavioral and biologic characteristics of cancer-related cognitive impairment biotypes. Brain Imaging Behav. 2023;17:320–8.

Article  PubMed  PubMed Central  Google Scholar 

Hort J, O’Brien JT, Gainotti G, Pirttila T, Popescu BO, Rektorova I, et al. EFNS guidelines for the diagnosis and management of Alzheimer’s disease. Eur J Neurol. 2010;17:1236–48.

Article  CAS  PubMed  Google Scholar 

McDonald BC, Conroy SK, Ahles TA, West JD, Saykin AJ. Alterations in brain activation during working memory processing associated with breast cancer and treatment: a prospective functional magnetic resonance imaging study. J Clin Oncol. 2012;30:2500–8.

Article  PubMed  PubMed Central  Google Scholar 

Vardy JL, Stouten-Kemperman MM, Pond G, Booth CM, Rourke SB, Dhillon HM, et al. A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer. Brain Imaging Behav. 2017;13:15–26.

Article  Google Scholar 

Underwood EA, Rochon PA, Moineddin R, Lee PE, Wu W, Pritchard KI, et al. Cognitive sequelae of endocrine therapy in women treated for breast cancer: a meta-analysis. Breast Cancer Res Treat. 2018;168:299–310.

Article  CAS  PubMed  Google Scholar