Bissell MCS, Kerlikowske K, Sprague BL, Tice JA, Gard CC, Tossas KY, et al. Breast cancer population attributable risk proportions associated with body mass index and breast density by race/ethnicity and menopausal status. Cancer Epidemiol Biomarkers Prev. 2020;29:2048–56.
Article CAS PubMed PubMed Central Google Scholar
Alimujiang A, Imm KR, Appleton CM, Colditz GA, Berkey CS, Toriola AT. Adiposity at age 10 and mammographic density among premenopausal women. Cancer Prev Res. 2018;11:287–94.
Alimujiang A, Appleton C, Colditz GA, Toriola AT. Adiposity during early adulthood, changes in adiposity during adulthood, attained adiposity, and mammographic density among premenopausal women. Breast Cancer Res Treat. 2017;166:197–206. https://doi.org/10.1007/s10549-017-4384-4.
Moore JX, Han Y, Appleton C, Colditz G, Toriola AT. Determinants of mammographic breast density by race among a large screening population. JNCI Cancer Spectr. 2020. https://doi.org/10.1093/jncics/pkaa010/5758266.
Article PubMed PubMed Central Google Scholar
Dettmer K, Aronov PA, Hammock BD. Mass spectrometry-based metabolomics. Mass Spectrom Rev. 2007;26:51–78.
Article CAS PubMed PubMed Central Google Scholar
Mcclain KM, Friedenreich CM, Matthews CE, Sampson JN, Check DP, Brenner DR, et al. Body composition and metabolomics in the Alberta physical activity and breast cancer prevention trial. J Nutr. 2022;152:419–28. https://doi.org/10.1093/jn/nxab388.
Article CAS PubMed Google Scholar
Stevens VL, Carter BD, McCullough ML, Campbell PT, Wang Y. Metabolomic profiles associated with BMI, waist circumference, and diabetes and inflammation biomarkers in women. Obesity. 2020;28:187–96.
Article CAS PubMed Google Scholar
Carayol M, Leitzmann MF, Ferrari P, Zamora-Ros R, Achaintre D, Stepien M, et al. Blood metabolic signatures of body mass index: a targeted metabolomics study in the EPIC cohort. J Proteome Res. 2017;16:3137–46.
Article CAS PubMed PubMed Central Google Scholar
Quehenberger O, Dennis EA. The human plasma lipidome. N Engl J Med. 2011;365:1812–23.
Article CAS PubMed PubMed Central Google Scholar
Gerl MJ, Klose C, Surma MA, Fernandez C, Melander O, Männistö S, et al. Machine learning of human plasma lipidomes for obesity estimation in a large population cohort. PLoS Biol. 2019;17:1–25.
Rauschert S, Uhl O, Koletzko B, Kirchberg F, Mori TA, Huang RC, et al. Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults. J Clin Endocrinol Metab. 2016;101:871–9.
Article CAS PubMed Google Scholar
Yin R, Wang X, Li K, Yu K, Yang L. Lipidomic profiling reveals distinct differences in plasma lipid composition in overweight or obese adolescent students. BMC Endocr Disord. 2021;21:1–10.
Wang Y, Jiang CT, Song JY, Song QY, Ma J, Wang HJ. Lipidomic profile revealed the association of plasma lysophosphatidylcholines with adolescent obesity. Biomed Res Int. 2019;2019:1–9.
Beyene HB, Olshansky G, Smith AAT, Giles C, Huynh K, Cinel M, et al. High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: evidence from two large population cohort studies. PLoS Biol. 2020. https://doi.org/10.1371/journal.pbio.3000870.
Article PubMed PubMed Central Google Scholar
Matthew KA, Getz KR, Jeon MS, Luo C, Luo J, Toriola AT. Associations of vitamins and related cofactor metabolites with mammographic breast density in premenopausal women. J Nutr. 2024;154:424–34.
Article CAS PubMed Google Scholar
Jung S, Silva S, Dallal CM, LeBlanc E, Paris K, Shepherd J, et al. Untargeted serum metabolomic profiles and breast density in young women. Cancer Causes Control. 2024;35:323–34. https://doi.org/10.1007/s10552-023-01793-w.
Getz KR, Jeon MS, Luo C, Luo J, Toriola AT. Lipidome of mammographic breast density in premenopausal women. Breast Cancer Res. 2023;25:1–13. https://doi.org/10.1186/s13058-023-01725-1.
Dorgan JF, Baer HJ, Bertrand KA, LeBlanc ES, Jung S, Magder LS, et al. Childhood adiposity, serum metabolites and breast density in young women. Breast Cancer Res. 2022;24:1–11. https://doi.org/10.1186/s13058-022-01588-y.
Toriola AT, Appleton CM, Zong X, Luo J, Weilbaecher K, Tamimi RM, et al. Circulating receptor activator of nuclear factor-κB (RANK), RANK ligand (RANKL), and mammographic density in premenopausal women. Cancer Prev Res. 2018;11:789–96.
Berkey CS, Rockett HRH, Field AE, Gillman MW, Frazier AL, Camargo CA, et al. Activity, dietary intake, and weight changes in a longitudinal study of preadolescent and adolescent boys and girls. Pediatrics. 2000;105:e56–e56.
Article CAS PubMed Google Scholar
Metabolon. Complex Lipids Targeted Panel. [cited 2023 May 18]. Available from: https://www.metabolon.com/lp/complex-lipid-panel/
Hastie T, Tibshirani R, Narasimhan B, Chu G. Impute: impute: imputation for microarray data_.R package version 1.70.0. 2022.
Collet TH, Sonoyama T, Henning E, Keogh JM, Ingram B, Kelway S, et al. A metabolomic signature of acute caloric restriction. J Clin Endocrinol Metab. 2017;102:4486–95.
Article PubMed PubMed Central Google Scholar
Troyanskaya O, Cantor M, Sherlock G, Brown P, Hastie T, Tibshirani R, et al. Missing value estimation methods for DNA microarrays. Bioinformatics. 2001;17:520–5.
Article CAS PubMed Google Scholar
Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007;8:118–27.
van Buuren S, Groothuis-Oudshoorn K. Mice: multivariate imputation by chained equations in R. J Stat Softw. 2011. https://doi.org/10.18637/jss.v045.i03.
Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, et al. Estimating and testing high-dimensional mediation effects in epigenetic studies. Bioinformatics. 2016;32:3150–4.
Article CAS PubMed PubMed Central Google Scholar
Moore SC, Matthews CE, Sampson JN, Stolzenberg-Solomon RZ, Zheng W, Cai Q, et al. Human metabolic correlates of body mass index. Metabolomics. 2014;10:259–69.
Article CAS PubMed Google Scholar
Butte NF, Liu Y, Zakeri IF, Mohney RP, Mehta N, Voruganti VS, et al. Global metabolomic profiling targeting childhood obesity in the Hispanic population. Am J Clin Nutr. 2015;102:256–67.
Article CAS PubMed PubMed Central Google Scholar
Müllner E, Röhnisch HE, von Brömssen C, Moazzami AA. Metabolomics analysis reveals altered metabolites in lean compared with obese adolescents and additional metabolic shifts associated with hyperinsulinaemia and insulin resistance in obese adolescents: a cross-sectional study. Metabolomics. 2021;17:1–13.
Maltais-Payette I, Boulet M-M, Prehn C, Adamski J, Tchernof A. Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations. Nutr Metab. 2018;15:78.
Maltais-Payette I, Allam-Ndoul B, Pérusse L, Vohl M-C, Tchernof A. Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk. Nutr Metab Cardiovasc Dis. 2019;29:1353–60.
Article CAS PubMed Google Scholar
Nagao H, Nishizawa H, Bamba T, Nakayama Y, Isozumi N, Nagamori S, et al. Increased dynamics of tricarboxylic acid cycle and glutamate synthesis in obese adipose tissue: in vivo metabolic turnover analysis. J Biol Chem. 2017;292:4469–83.
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