Helicobacter pylori and gastric cancer: mechanisms and new perspectives

Arnold M, Park JY, Camargo MC, Lunet N, Forman D, Soerjomataram I. Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035. Gut. 2020;69(5):823–29.

Article  PubMed  Google Scholar 

Sitarz R, Skierucha M, Mielko J, Offerhaus GJA, Maciejewski R, Polkowski WP. Gastric cancer: epidemiology, prevention, classification, and treatment. Cancer Manag Res. 2018;10:239–48.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229–63.

Article  PubMed  Google Scholar 

Hooi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D, et al. Global prevalence of Helicobacter pylori infection: systematic review and Meta-analysis. Gastroenterology. 2017;153(2):420–29.

Article  PubMed  Google Scholar 

Gu Y, Xu Y, Wang P, Zhao Y, Wan C. Research progress on molecular mechanism of pyroptosis caused by Helicobacter pylori in gastric cancer. Ann Med Surg (Lond). 2024;86(4):2016–22.

Article  PubMed  Google Scholar 

Correa P. A human model of gastric carcinogenesis. Cancer Res. 1988;48(13):3554–60.

CAS  PubMed  Google Scholar 

Warren JR, Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet. 1983;1(8336):1273–5.

CAS  PubMed  Google Scholar 

Malfertheiner P, Link A, Selgrad M. Helicobacter pylori: perspectives and time trends. Nat Rev Gastroenterol Hepatol. 2014;11(10):628–38.

Article  PubMed  Google Scholar 

Pincock S. Nobel Prize winners Robin Warren and Barry Marshall. Lancet. 2005;366(9495):1429.

Article  PubMed  Google Scholar 

Correa P. Human gastric carcinogenesis: a multistep and multifactorial process–first American Cancer Society Award lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992;52(24):6735–40.

CAS  PubMed  Google Scholar 

Schistosomes. Liver flukes and Helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum. 1994;61:1–241.

Google Scholar 

Linz B, Balloux F, Moodley Y, Manica A, Liu H, Roumagnac P, et al. An African origin for the intimate association between humans and Helicobacter pylori. Nature. 2007;445(7130):915–18.

Article  PubMed  PubMed Central  Google Scholar 

Li Y, Hahn AI, Laszkowska M, Jiang F, Zauber AG, Leung WK. Global burden of young-onset gastric cancer: a systematic trend analysis of the global burden of disease study 2019. Gastric Cancer. 2024;27(4):684–700.

Article  PubMed  PubMed Central  Google Scholar 

Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med. 2002;347(15):1175–86.

Article  CAS  PubMed  Google Scholar 

Duan M, Li Y, Liu J, Zhang W, Dong Y, Han Z, et al. Transmission routes and patterns of helicobacter pylori. Helicobacter. 2023;28(1):e12945.

Article  PubMed  Google Scholar 

Weyermann M, Rothenbacher D, Brenner H. Acquisition of Helicobacter pylori infection in early childhood: independent contributions of infected mothers, fathers, and siblings. Am J Gastroenterol. 2009;104(1):182–9.

Article  PubMed  Google Scholar 

Chen YC, Malfertheiner P, Yu HT, Kuo CL, Chang YY, Meng FT, et al. Global prevalence of Helicobacter pylori infection and incidence of gastric Cancer between 1980 and 2022. Gastroenterology. 2024;166(4):605–19.

Article  PubMed  Google Scholar 

Park JS, Jun JS, Seo JH, Youn HS, Rhee KH. Changing prevalence of Helicobacter pylori infection in children and adolescents. Clin Exp Pediatr. 2021;64(1):21–5.

Article  PubMed  Google Scholar 

Liou JM, Malfertheiner P, Lee YC, Sheu BS, Sugano K, Cheng HC, et al. Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus. Gut. 2020;69(12):2093–112.

Article  PubMed  Google Scholar 

Yuan C, Adeloye D, Luk TT, Huang L, He Y, Xu Y, et al. The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis. Lancet Child Adolesc Health. 2022;6(3):185–94.

Article  PubMed  Google Scholar 

Salama NR, Hartung ML, Müller A. Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol. 2013;11(6):385–99.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Olbermann P, Josenhans C, Moodley Y, Uhr M, Stamer C, Vauterin M, et al. A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island. PLoS Genet. 2010;6(8):e1001069.

Article  PubMed  PubMed Central  Google Scholar 

Ding SZ, Zheng PY. Helicobacter pylori infection induced gastric cancer; advance in gastric stem cell research and the remaining challenges. Gut Pathog. 2012;4(1):18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Poppe M, Feller SM, Römer G, Wessler S. Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility. Oncogene. 2007;26(24):3462–72.

Article  CAS  PubMed  Google Scholar 

Hatakeyama M. Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer. 2004;4(9):688–94.

Article  CAS  PubMed  Google Scholar 

Backert S, Tegtmeyer N, Fischer W. Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system. Future Microbiol. 2015;10(6):955–65.

Article  CAS  PubMed  Google Scholar 

Baj J, Forma A, Sitarz M, Portincasa P, Garruti G, Krasowska D, et al. Helicobacter pylori Virulence Factors-Mechanisms of bacterial pathogenicity in the gastric microenvironment. Cells. 2020;10(1):27.

Article  PubMed  PubMed Central  Google Scholar 

Kim IJ, Lee J, Oh SJ, Yoon MS, Jang SS, Holland RL, et al. Helicobacter pylori infection modulates host cell metabolism through VacA-Dependent inhibition of mTORC1. Cell Host Microbe. 2018;23(5):583–e938.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bridge DR, Merrell DS. Polymorphism in the Helicobacter pylori CagA and VacA toxins and disease. Gut Microbes. 2013;4(2):101–17.

Article  PubMed  PubMed Central  Google Scholar 

Whitmire JM, Merrell DS. Helicobacter pylori genetic polymorphisms in gastric Disease Development. Adv Exp Med Biol. 2019;1149:173–94.

Article  CAS  PubMed  Google Scholar 

Letley DP, Lastovica A, Louw JA, Hawkey CJ, Atherton JC. Allelic diversity of the Helicobacter pylori vacuolating cytotoxin gene in South Africa: rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele. J Clin Microbiol. 1999;37(4):1203–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Debowski AW, Walton SM, Chua EG, Tay AC, Liao T, Lamichhane B, et al. Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection. PLoS Pathog. 2017;13(6):e1006464.

Article  PubMed  PubMed Central  Google Scholar 

Gu H. Role of Flagella in the pathogenesis of Helicobacter pylori. Curr Microbiol. 2017;74(7):863–69.

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif