Yan Bian, Ye Gao, Han Lin and Chang Sun contributed equally to this work.

Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China

Yan Bian, Ye Gao, Han Lin, Chang Sun, Wei Wang, Lei Xin, Zhaoshen Li & Luowei Wang

Changhai Clinical Research Unit, Changhai Hospital, Naval Medical University, Shanghai, China

Yan Bian, Ye Gao, Han Lin, Chang Sun, Wei Wang, Lei Xin, Zhaoshen Li & Luowei Wang

National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, China

Yan Bian, Ye Gao, Chang Sun, Lei Xin, Zhaoshen Li & Luowei Wang

Department of Gastroenterology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

Siyu Sun

Department of Gastroenterology, Henan Provincial People’s Hospital, Zhengzhou, Henan, China

Xiuling Li

Department of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, Hebei, China

Zhijie Feng

Department of Gastroenterology, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China

Jianlin Ren

Department of Thoracic Surgery, Changhai Hospital, Naval Medical University, Shanghai, China

Hezhong Chen & Chaojing Lu

Department of Health Statistics, Naval Medical University, Shanghai, China

Jinfang Xu

Wuhan Ammunition Life-Tech Company, Ltd., Wuhan, Hubei, China

Jun Zhou & Kangkang Wan