Bhatla N, Aoki D, Sharma DN, Sankaranarayanan R. Cancer of the cervix uteri: 2021 update. Int J Gynecol Obstet. 2021;155:28–44.
Chan CK, Aimagambetova G, Ukybassova T, Kongrtay K, Azizan A. Human papillomavirus infection and cervical cancer: epidemiology, screening, and vaccination—review of current perspectives. J Oncol. 2019;2019:1–11.
Ireton R, Chen J. EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. Curr Cancer Drug Targets. 2005;5:149–57.
Article CAS PubMed Google Scholar
Huang C, Yuan W, Lai C, Zhong S, Yang C, Wang R, Mao L, Chen Z, Chen Z. EphA2-to-YAP pathway drives gastric cancer growth and therapy resistance. Int J Cancer. 2020;146:1937–49.
Article CAS PubMed Google Scholar
Brannan JM, Sen B, Saigal B, Prudkin L, Behrens C, Solis L, Dong W, Bekele BN, Wistuba I, Johnson FM. EphA2 in the early pathogenesis and progression of non-small cell lung cancer. Cancer Prev Res (Phila Pa). 2009;2:1039–49.
Xu J, Zhang J, Cui L, Zhang H, Zhang S, Bai Y. High EphA2 protein expression in renal cell carcinoma is associated with a poor disease outcome. Oncol Lett. 2014;8:687–92.
Article CAS PubMed PubMed Central Google Scholar
Dunne PD, Dasgupta S, Blayney JK, et al. EphA2 expression is a key driver of migration and invasion and a poor prognostic marker in colorectal cancer. Clin Cancer Res. 2016;22:230–42.
Article CAS PubMed Google Scholar
Hudecek R, Kohlova B, Siskova I, Piskacek M, Knight A. Blocking of EphA2 on endometrial tumor cells reduces susceptibility to Vδ1 Gamma-delta T-cell-mediated killing. Front Immunol. 2021;12: 752646.
Article CAS PubMed PubMed Central Google Scholar
Huang C, Chen Z, He Y, et al. EphA2 promotes tumorigenicity of cervical cancer by up-regulating CDK6. J Cell Mol Med. 2021;25:2967–75.
Article CAS PubMed PubMed Central Google Scholar
Miao H, Gale NW, Guo H, et al. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene. 2015;34:558–67.
Article CAS PubMed Google Scholar
Han B, Zhang H, Tian R, et al. Exosomal EPHA2 derived from highly metastatic breast cancer cells promotes angiogenesis by activating the AMPK signaling pathway through Ephrin A1-EPHA2 forward signaling. Theranostics. 2022;12:4127–46.
Article CAS PubMed PubMed Central Google Scholar
Liang S, Wang Q, Wen Y, Wang Y, Li M, Wang Q, Peng J, Guo L. Ligand-independent EphA2 contributes to chemoresistance in small-cell lung cancer by enhancing PRMT1 -mediated SOX2 methylation. Cancer Sci. 2023;114:921–36.
Article CAS PubMed Google Scholar
Multhoff G, Molls M, Radons J. Chronic inflammation in cancer development. Front Immunol. 2012. https://doi.org/10.3389/fimmu.2011.00098.
Article PubMed PubMed Central Google Scholar
Hirano T. IL-6 in inflammation, autoimmunity and cancer. Int Immunol. 2021;33:127–48.
Article CAS PubMed Google Scholar
Tanaka T, Narazaki M, Kishimoto T. IL-6 in inflammation, immunity, and disease. Cold Spring Harb Perspect Biol. 2014;6:a016295.
Article PubMed PubMed Central Google Scholar
Huang B, Lang X, Li X. The role of IL-6/JAK2/STAT3 signaling pathway in cancers. Front Oncol. 2022;12:1023177.
Article CAS PubMed PubMed Central Google Scholar
Pinno J, Bongartz H, Klepsch O, Wundrack N, Poli V, Schaper F, Dittrich A. Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner. Cell Signal. 2016;28:907–16.
Article CAS PubMed Google Scholar
Stoll G, Zitvogel L, Kroemer G. Immune infiltrate in cancer. Aging. 2015;7:358–9.
Article CAS PubMed PubMed Central Google Scholar
Barzegar Behrooz A, Syahir A, Ahmad S. CD133: beyond a cancer stem cell biomarker. J Drug Target. 2019;27:257–69.
Article CAS PubMed Google Scholar
Brugnoli F, Grassilli S, Al-Qassab Y, Capitani S, Bertagnolo V. CD133 in breast cancer cells: more than a stem cell marker. J Oncol. 2019;2019:1–8.
Glumac PM, LeBeau AM. The role of CD133 in cancer: a concise review. Clin Transl Med. 2018;7: e18.
Kawaguchi K, Asano S. Pathophysiological roles of actin-binding scaffold protein. Ezrin Int J Mol Sci. 2022;23:3246.
Article CAS PubMed Google Scholar
Song Y, Ma X, Zhang M, Wang M, Wang G, Ye Y, Xia W. Ezrin mediates invasion and metastasis in tumorigenesis: a review. Front Cell Dev Biol. 2020;8: 588801.
Article PubMed PubMed Central Google Scholar
Riera Leal A, Ortiz-Lazareno P, Jave-Suárez L, et al. 17β-estradiol-induced mitochondrial dysfunction and Warburg effect in cervical cancer cells allow cell survival under metabolic stress. Int J Oncol. 2019. https://doi.org/10.3892/ijo.2019.4912.
Song P, Li Y, Dong Y, et al. Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy. J Exp Clin Cancer Res. 2019;38:354.
Article PubMed PubMed Central Google Scholar
Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45:W98-102.
Article CAS PubMed PubMed Central Google Scholar
Chandrashekar DS, Karthikeyan SK, Korla PK, et al. UALCAN: An update to the integrated cancer data analysis platform. Neoplasia. 2022;25:18–27.
Article CAS PubMed PubMed Central Google Scholar
Lánczky A, Győrffy B. Web-based survival analysis tool tailored for medical research (KMplot): development and implementation. J Med Internet Res. 2021;23: e27633.
Article PubMed PubMed Central Google Scholar
Chugh PE, Sin S-H, Ozgur S, Henry DH, Menezes P, Griffith J, Eron JJ, Damania B, Dittmer DP. Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies. PLoS Pathog. 2013;9: e1003484.
Article CAS PubMed PubMed Central Google Scholar
Bairoch A. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. Nucleic Acids Res. 2000;28:45–8.
Article CAS PubMed PubMed Central Google Scholar
Kozakov D, Hall DR, Xia B, Porter KA, Padhorny D, Yueh C, Beglov D, Vajda S. The ClusPro web server for protein–protein docking. Nat Protoc. 2017;12:255–78.
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