Wu N, Zheng W, Zhou Y, Tian Y, Tang M, Feng X, et al. Autophagy in aging-related diseases and cancer: principles, regulatory mechanisms and therapeutic potential. Ageing Res Rev. 2024;100:102428.
Yang Y, Liu L, Tian Y, Gu M, Wang Y, Ashrafizadeh M, et al. Autophagy-driven regulation of cisplatin response in human cancers: exploring molecular and cell death dynamics. Cancer Lett. 2024;587:216659.
Guo Y, Ashrafizadeh M, Tambuwala MM, Ren J, Orive G, Yu G. P-glycoprotein (P-gp)-driven cancer drug resistance: biological profile, non-coding RNAs, drugs and nanomodulators. Drug Discov Today. 2024;29:104161.
Zang C, Tian Y, Tang Y, Tang M, Yang D, Chen F, et al. Hydrogel-based platforms for site-specific doxorubicin release in cancer therapy. J Transl Med. 2024;22:879.
Article PubMed PubMed Central Google Scholar
Cheaib B, Auguste A, Leary A. The PI3K/Akt/mTOR pathway in ovarian cancer: Therapeutic opportunities and challenges. Chin J Cancer. 2015;34:4–16.
Article PubMed PubMed Central Google Scholar
Hussain Y, Abdullah AKF, Aschner M, Theyab A, Khan F, et al. Therapeutic role of carotenoids in blood cancer: mechanistic insights and therapeutic potential. Nutrients. 2022;14:1949.
Article PubMed PubMed Central Google Scholar
Bolhassani A, Milani A, Basirnejad M, Shahbazi S. Carotenoids: biochemistry, pharmacology and treatment. Br J Pharmacol [Internet]. 2017;174:1290. http://onlinelibrary.wiley.com/doi/https://doi.org/10.1111/bph.v174.11/
Peng Y, Wang Y, Zhou C, Mei W, Zeng C. PI3K/Akt/mTOR pathway and its role in cancer therapeutics: are we making headway? Front Oncol. 2022. https://doi.org/10.3389/fonc.2022.819128.
Article PubMed PubMed Central Google Scholar
Giani M, Montoyo-Pujol YG, Peiró G, Martínez-Espinosa RM. Halophilic carotenoids and breast cancer: From salt marshes to biomedicine. Mar Drugs. 2021;19.
Saini RK, Keum YS, Daglia M, Rengasamy KR. Dietary carotenoids in cancer chemoprevention and chemotherapy: A review of emerging evidence. Pharmacol Res. 2020;157.
Maoka T. Carotenoids as natural functional pigments. J Nat Med. 2020;74:16.
Crupi P, Faienza MF, Naeem MY, Corbo F, Clodoveo ML, Muraglia M. Overview of the potential beneficial effects of carotenoids on consumer health and well-being. Antioxidants. 2023;12:1069.
Article PubMed PubMed Central Google Scholar
Fiedor J, Burda K. Potential role of carotenoids as antioxidants in human health and disease. Nutrients. 2014;6:466–88.
Article PubMed PubMed Central Google Scholar
Furubayashi M, Ikezumi M, Takaichi S, Maoka T, Hemmi H, Ogawa T, et al. A highly selective biosynthetic pathway to non-natural C 50 carotenoids assembled from moderately selective enzymes. Nat Commun. 2015. https://doi.org/10.1038/ncomms8534.
Terao J. Revisiting carotenoids as dietary antioxidants for human health and disease prevention. Food Funct. 2023;14:7799–824.
Starska-Kowarska K. Dietary carotenoids in head and neck cancer—molecular and clinical implications. Nutrients. 2022;14:531.
Article PubMed PubMed Central Google Scholar
Varghese R, Efferth T, Ramamoorthy S. Carotenoids for lung cancer chemoprevention and chemotherapy: promises and controversies. Phytomedicine. 2023;116:154850.
Sharoni Y, Linnewiel-Hermoni K, Zango G, Khanin M, Salman H, Veprik A, et al. The role of lycopene and its derivatives in the regulation of transcription systems: Implications for cancer prevention. Am J Clin Nutr. 2012;96:1173S-S1178.
Chen QH, Wu BK, Pan D, Sang LX, Chang B. Beta-carotene and its protective effect on gastric cancer. World J Clin Cases. 2021;9:6591–607.
Article PubMed PubMed Central Google Scholar
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B. β -Carotene attenuates apoptosis and autophagy via PI3K/AKT/mTOR signaling pathway in necrotizing enterocolitis model cells IEC-6. Evidence-based Complement Altern Med. 2022;2022:2502263.
Qi WJ, Sheng WS, Peng C, Xiaodong M, Yao TZ. Investigating into anti-cancer potential of lycopene: molecular targets. Biomed Pharmacother. 2021;138:111546.
Paplomata E, O’regan R. The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers. Ther Adv Med Oncol. 2014;6:154–66.
Article PubMed PubMed Central Google Scholar
Hassan M, Watari H, Abualmaaty A, Ohba Y, Sakuragi N. Apoptosis and molecular targeting therapy in cancer. Biomed Res Int. 2014;2014:150845.
Article PubMed PubMed Central Google Scholar
Tanaka T, Shnimizu M, Moriwaki H. Cancer chemoprevention by carotenoids. Molecules. 2012;17:3202–42.
Article PubMed PubMed Central Google Scholar
M. Z, Z. NR, E. A, S.M. J. Improving the cancer prevention/treatment role of carotenoids through various nano-delivery systems. Crit Rev Food Sci Nutr [Internet]. 2020;1–13. Available from: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L631268483%0Ahttps://doi.org/10.1080/10408398.2020.1738999
Rowles JL, Erdman JW. Carotenoids and their role in cancer prevention. Biochim Biophys Acta - Mol Cell Biol Lipids. 2020;1865:158613.
Bohn T, Balbuena E, Ulus H, Iddir M, Wang G, Crook N, et al. Carotenoids in health as studied by omics-related endpoints. Adv Nutr. 2023;14:1538–78.
Article PubMed PubMed Central Google Scholar
Burris HA III. Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway. Cancer Chemother Pharmacol. 2013;71:829–42.
Stern DF. ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. J Mammary Gland Biol Neoplasia. 2008;13:215–23.
Article PubMed PubMed Central Google Scholar
Manuscript A, Dysfunction E. Class I PI3K in oncogenic cellular transformation. Oncogene. 2008;27:5486–96.
Agoulnik IU, Hodgson MC, Bowden WA, Ittmann MM. INPP4b: the new kid on the PI3K block. Oncotarget. 2011;2:321–8.
Article PubMed PubMed Central Google Scholar
Cantley LC. The phosphoinositide 3-kinase pathway. Science. 2002;296:1655–7.
Engelman JA, Luo J, Cantley LC. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat Rev Genet. 2006;7:606–19.
Jaber L, Shaban S, Hariri D. Oral cancer prevention and early detection: Knowledge and practice among Saudi Arabian healthcare practitioners. Int J Health Care Qual Assur. 2012;25:64–74.
Janku F, McConkey DJ, Hong DS, Kurzrock R. Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol. 2011;8:528–39.
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, et al. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A. 2007;104:20007–12.
Article PubMed PubMed Central Google Scholar
Bendell JC, Rodon J, Burris HA, De Jonge M, Verweij J, Birle D, et al. Phase I, dose-escalation study of BKM120, an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors. J Clin Oncol. 2012;30:282–90.
Tsimberidou AM, Iskander NG, Hong DS, Wheler JJ, Falchook GS, Fu S, et al. Personalized medicine in a phase I clinical trials program: the MD anderson cancer center initiative. Clin Cancer Res. 2012;18:6373–83.
留言 (0)