Luo P, Chen G, Shi Z, Yang J, Wang X, Pan J, Zhu L. Comprehensive multi-omics analysis of tryptophan metabolism-related gene expression signature to predict prognosis in gastric cancer. Front Pharmacol. 2023;14:1267186.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang J, Wei W, Xu Y, Chen K, Miao Y, Fan W, et al. CXC chemokine receptor 4-mediated immune modulation and tumor microenvironment heterogeneity in gastric cancer: Utilizing multi-omics approaches to identify potential therapeutic targets. BioFactors. 2024;2024:1.

Google Scholar 

Wang L, Zhou X, Yan H, Miao Y, Wang B, Gu Y, et al. Deciphering the role of tryptophan metabolism-associated genes ECHS1 and ALDH2 in gastric cancer: implications for tumor immunity and personalized therapy. Front Immunol. 2024;15: 1460308.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen X, Chi H, Zhao X, Pan R, Wei Y, Han Y. Role of exosomes in immune microenvironment of hepatocellular carcinoma. J Oncol. 2022;2022: 2521025.

PubMed  PubMed Central  Google Scholar 

Seeneevassen L, Zaafour A, Sifré E, Genevois C, Nguyen TL, Pobiedonoscew Y, et al. Targeting metastasis-initiating cancer stem cells in gastric cancer with leukaemia inhibitory factor. Cell Death Discov. 2024;10:120.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Su K, Shen Q, Tong J, Gu T, Xu K, Li H, et al. Construction and validation of a nomogram for HBV-related hepatocellular carcinoma: a large, multicenter study. Ann Hepatol. 2023;28: 101109.

Article  CAS  PubMed  Google Scholar 

Bleve A, Durante B, Sica A, Consonni FM. Lipid metabolism and cancer immunotherapy: immunosuppressive myeloid cells at the crossroad. Int J Mol Sci. 2020;21:5845.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li H, Guo L, Su K, Li C, Jiang Y, Wang P, et al. Construction and validation of TACE therapeutic efficacy by ALR score and nomogram: a large, multicenter study. J Hepatocell Carcinoma. 2023;10:1009–17.

Article  PubMed  PubMed Central  Google Scholar 

Su K, Liu Y, Wang P, He K, Wang F, Chi H, et al. Heat-shock protein 90α is a potential prognostic and predictive biomarker in hepatocellular carcinoma: a large-scale and multicenter study. Hepatol Int. 2022;16:1208–19.

Article  PubMed  Google Scholar 

Jiang L, Zhang S, Jiang C, Chen H, Huang J, Yang J, et al. Integrative biomarker discovery and immune profiling for ulcerative colitis: a multi-methodological approach. Sci Rep. 2024;14:24290.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gu Y, Jiang L, Shui M, Luo H, Zhou X, Zhang S, Jiang C, Huang J, Chen H, Tang J, Fu Y, Luo H, Yang G, Xu K, Chi H, Liu J, Huang S. Revealing the association between East Asian oral microbiome and colorectal cancer through Mendelian randomization and multi-omics analysis. Front Cell Infect Microbiol. 2024;14:1452392.

Article  PubMed  PubMed Central  Google Scholar 

Jiang L, Liu J, Zhang S, Jiang C, Huang J, Chen H, et al. Role of glycosylation-related gene MGAT1 in pancreatic ductal adenocarcinoma. Front Immunol. 2024;15:1438935.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu Y, Cheng Y, Wang X, Fan J, Gao Q. Spatial omics: navigating to the golden era of cancer research. Clin Transl Med. 2022;12: e696.

Article  PubMed  PubMed Central  Google Scholar 

Tu H, Hu Q, Ma Y, Huang J, Luo H, Jiang L, et al. Chen, Deciphering the tumour microenvironment of clear cell renal cell carcinoma: prognostic insights from programmed death genes using machine learning. J Cell Mol Med. 2024;28: e18524.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang L, Ren X, Yang J, Chen H, Zhang S, Zhou X, et al. Mitophagy and clear cell renal cell carcinoma: insights from single-cell and spatial transcriptomics analysis. Front Immunol. 2024;15:1400431.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tang J, Zhang S, Jiang L, Liu J, Xu J, Jiang C, Chi H, et al. Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study. J Cancer. 2024;15:4219–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen H, Zuo H, Huang J, Liu J, Jiang L, Jiang C, et al. Unravelling infiltrating T-cell heterogeneity in kidney renal clear cell carcinoma: integrative single-cell and spatial transcriptomic profiling. J Cell Mol Med. 2024;28: e18403.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang C, Zhang S, Jiang L, Chen Z, Chen H, Huang J, et al. Precision unveiled: synergistic genomic landscapes in breast cancer-Integrating single-cell analysis and decoding drug toxicity for elite prognostication and tailored therapeutics. Environ Toxicol. 2024;39:3448–72.

Article  CAS  PubMed  Google Scholar 

Hsieh WC, Budiarto BR, Wang YF, Lin CY, Gwo MC, So DK, et al. Chen, Spatial multi-omics analyses of the tumor immune microenvironment. J Biomed Sci. 2022;29:96.

Article  PubMed  PubMed Central  Google Scholar 

Xing QR, Cipta NO, Hamashima K, Liou YC, Koh CG, Loh YH. Unraveling heterogeneity in transcriptome and its regulation through single-cell multi-omics technologies. Front Genet. 2020;11:662.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng H, Wang M, Su J, Li Y, Long J, Chu J, Li Q, et al. Lipid metabolism and cancer. Life (Basel). 2022;12:784.

CAS  PubMed  Google Scholar 

He L, Ye Q, Zhu Y, Zhong W, Xu G, Wang L, et al. Lipid metabolism-related gene signature predicts prognosis and indicates immune microenvironment infiltration in advanced gastric cancer. Gastroenterol Res Pract. 2024;2024:6639205.

Article  PubMed  PubMed Central  Google Scholar 

Kollara A, Brown TJ. Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity. Cell Mol Life Sci. 2012;69:3895–909.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mou Y, Wu J, Zhang Y, Abdihamid O, Duan C, Li B. Low expression of ferritinophagy-related NCOA4 gene in relation to unfavorable outcome and defective immune cells infiltration in clear cell renal carcinoma. BMC Cancer. 2021;21:18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gu C, Chang W, Wu J, Yao Y, Liu G, Yuan Y, et al. NCOA4: an immunomodulation-related prognostic biomarker in colon adenocarcinoma and pan-cancer. J Oncol. 2022;2022:5242437.

Article  PubMed  PubMed Central  Google Scholar 

Christianson J, Oxford JT, Jorcyk CL. Emerging perspectives on leukemia inhibitory factor and its receptor in cancer. Front Oncol. 2021;11: 693724.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang F, Wang Y, Li H, Li L, Yang X, You X, et al. Pan-cancer analysis identifies LIFR as a prognostic and immunological biomarker for uterine corpus endometrial carcinoma. Front Oncol. 2023;13:1118906.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang S, Sun B, Li W, Yang H, Li N, Zhang X. Fatty acid metabolism is related to the immune microenvironment changes of gastric cancer and RGS2 is a new tumor biomarker. Front Immunol. 2022;13:1065927.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang J, Wang H, Tian Y, Li T, Zhang W, Ma L, et al. Discovery of a novel lipid metabolism-related gene signature to predict outcomes and the tumor immune microenvironment in gastric cancer by integrated analysis of single-cell and bulk RNA sequencing. Lipids Health Dis. 2023;22:212.

Article  CAS