Bardo MT, Bevins RA (2000) Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology 153:31–43. https://doi.org/10.1007/s002130000569
Article PubMed CAS Google Scholar
Breivogel CS, Wells JR, Jonas A et al (2020) Comparison of the neurotoxic and seizure-inducing effects of Synthetic and endogenous cannabinoids with ∆ 9 -Tetrahydrocannabinol. Cannabis Cannabinoid Res 5:32–41. https://doi.org/10.1089/can.2019.0003
Article PubMed PubMed Central CAS Google Scholar
Canazza I, Ossato A, Trapella C et al (2016) Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on tetrad, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies. Psychopharmacology 233:3685–3709. https://doi.org/10.1007/s00213-016-4402-y
Article PubMed CAS Google Scholar
Diao X, Carlier J, Zhu M et al (2017) In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201). Forensic Toxicol 35:20–32. https://doi.org/10.1007/s11419-016-0326-9
Article PubMed CAS Google Scholar
Falenski KW, Thorpe AJ, Schlosburg JE et al (2010) FAAH–/– mice Display Differential Tolerance, Dependence, and cannabinoid receptor adaptation after ∆9-Tetrahydrocannabinol and Anandamide Administration. Neuropsychopharmacology 35:1775–1787. https://doi.org/10.1038/npp.2010.44
Article PubMed PubMed Central CAS Google Scholar
Fogel JS, Kelly TH, Westgate PM, Lile JA (2017) Sex differences in the subjective effects of oral ∆9-THC in cannabis users. Pharmacol Biochem Behav 152:44–51. https://doi.org/10.1016/j.pbb.2016.01.007
Article PubMed CAS Google Scholar
Foll BL, Wiggins M, Goldberg SR (2006) Nicotine pre-exposure does not potentiate the locomotor or rewarding effects of D-9-tetrahydrocannabinol in rats. https://doi.org/10.1097/01.fbp.0000197460.16516.81
Gatch MB, Forster MJ (2018) ∆9-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats. Psychopharmacology 235:673–680. https://doi.org/10.1007/s00213-017-4783-6
Article PubMed CAS Google Scholar
Giorgetti A, Brunetti P, Haschimi B et al (2023) Human phase-I metabolism and prevalence of two synthetic cannabinoids bearing an ethyl ester moiety: 5F‐EDMB‐PICA and EDMB‐PINACA. Drug Test Anal 15:299–313. https://doi.org/10.1002/dta.3405
Article PubMed CAS Google Scholar
Halter S, Angerer V, Röhrich J et al (2019) Cumyl-PEGACLONE: a comparatively safe new synthetic cannabinoid receptor agonist entering the NPS market? Drug Test Anal 11:347–349. https://doi.org/10.1002/dta.2545
Article PubMed CAS Google Scholar
Hess C, Schoeder CT, Pillaiyar T et al (2016) Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice. Forensic Toxicol 34:329–343. https://doi.org/10.1007/s11419-016-0320-2
Article PubMed PubMed Central CAS Google Scholar
Higuera-Matas A, Miguéns M, Coria SM et al (2012) Sex-specific disturbances of the glutamate/GABA balance in the hippocampus of adult rats subjected to adolescent cannabinoid exposure. Neuropharmacology 62:1975–1984. https://doi.org/10.1016/j.neuropharm.2011.12.028
Article PubMed CAS Google Scholar
Howlett AC (2002) International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54:161–202. https://doi.org/10.1124/pr.54.2.161
Article PubMed CAS Google Scholar
Järbe TUC, Raghav JG (2016) Tripping with synthetic cannabinoids (spice): anecdotal and experimental observations in animals and man. In: Baumann MH, Glennon RA, Wiley JL (eds) Neuropharmacology of New Psychoactive substances (NPS). Springer International Publishing, Cham, pp 263–281
Lichtman AH, Fisher J, Martin BR (2001) Precipitated cannabinoid withdrawal is reversed by D9-tetrahydrocannabinol or clonidine. https://doi.org/10.1016/s0091-3057(01)00514-7
Long JZ, Li W, Booker L et al (2009) Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nat Chem Biol 5:37–44. https://doi.org/10.1038/nchembio.129
Article PubMed CAS Google Scholar
Luethi D, Liechti ME (2020) Designer drugs: mechanism of action and adverse effects. Arch Toxicol 94:1085–1133. https://doi.org/10.1007/s00204-020-02693-7
Article PubMed PubMed Central CAS Google Scholar
Lupica CR, Riegel AC, Hoffman AF (2004) Marijuana and cannabinoid regulation of brain reward circuits. Br J Pharmacol 143:227–234. https://doi.org/10.1038/sj.bjp.0705931
Article PubMed PubMed Central CAS Google Scholar
Mogler L, Wilde M, Huppertz LM et al (2018) Phase I metabolism of the recently emerged synthetic cannabinoid CUMYL-PEGACLONE and detection in human urine samples. Drug Test Anal 10:886–891. https://doi.org/10.1002/dta.2352
Article PubMed CAS Google Scholar
Nash C, Glowacki L, Gerostamoulos D et al (2019) Identification of a thermal degradation product of CUMYL-PEGACLONE and its detection in biological samples. Drug Test Anal 11:1480–1485. https://doi.org/10.1002/dta.2685
Article PubMed CAS Google Scholar
Nguyen JD, Aarde SM, Vandewater SA et al (2016) Inhaled delivery of ∆9-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology. Neuropharmacology 109:112–120. https://doi.org/10.1016/j.neuropharm.2016.05.021
Article PubMed PubMed Central CAS Google Scholar
Oliveira Da Cruz JF, Ioannidou C, Pagano Zottola AC et al (2021) Sex-dependent pharmacological profiles of the synthetic cannabinoid MMB‐Fubinaca. Addict Biol 26:e12940. https://doi.org/10.1111/adb.12940
Article PubMed CAS Google Scholar
Thomas BF, Lefever TW, Cortes RA et al (2017) Thermolytic degradation of Synthetic cannabinoids: Chemical exposures and Pharmacological consequences. J Pharmacol Exp Ther 361:162–171. https://doi.org/10.1124/jpet.116.238717
Article PubMed PubMed Central CAS Google Scholar
Trexler KR, Nass SR, Crowe MS et al (2018) Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice. Drug Alcohol Depend 191:14–24. https://doi.org/10.1016/j.drugalcdep.2018.05.029
Article PubMed PubMed Central CAS Google Scholar
Tseng AH, Craft RM (2001) Sex differences in antinociceptive and motoric effects of cannabinoids. Eur J Pharmacol 430:41–47. https://doi.org/10.1016/S0014-2999(01)01267-5
Article PubMed CAS Google Scholar
Varvel SA, Bridgen DT, Tao Q et al (2005) ∆ 9 -Tetrahydrocannbinol accounts for the Antinociceptive, hypothermic, and Cataleptic effects of Marijuana in mice. J Pharmacol Exp Ther 314:329–337. https://doi.org/10.1124/jpet.104.080739
Article PubMed CAS Google Scholar
Wiley JL, Lefever TW, Marusich JA, Craft RM (2017) Comparison of the discriminative stimulus and response rate effects of ∆9-tetrahydrocannabinol and synthetic cannabinoids in female and male rats. Drug Alcohol Depend 172:51–59. https://doi.org/10.1016/j.drugalcdep.2016.11.035
Article PubMed PubMed Central CAS Google Scholar
Wilson CD, Hiranita T, Fantegrossi WE (2022) Cannabimimetic effects of abused indazole-carboxamide synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA and 5F-ADB-PINACA in mice: Tolerance, dependence and withdrawal. Drug Alcohol Depend 236:109468. https://doi.org/10.1016/j.drugalcdep.2022.109468
Article PubMed CAS Google Scholar
Wouters E, Walraed J, Robertson MJ et al (2020) Assessment of biased agonism among distinct synthetic cannabinoid receptor agonist scaffolds. ACS Pharmacol Transl Sci 3:285–295. https://doi.org/10.1021/acsptsci.9b00069
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