Adams HP Jr, Effron MB, Torner J, Dávalos A, Frayne J, Teal P, Leclerc J, Oemar B, Padgett L, Barnathan ES, Hacke W (2008) Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II). Stroke 39(1):87–99. https://doi.org/10.1161/STROKEAHA.106.476648

Article  CAS  PubMed  Google Scholar 

Ahmad AF, Dwivedi G, O’Gara F, Caparros-Martin J, Ward NC (2019) The gut microbiome and cardiovascular disease: current knowledge and clinical potential. Am J Physiol Heart Circ Physiol 317(5):923–938. https://doi.org/10.1152/ajpheart.00376.2019

Article  CAS  Google Scholar 

Al Bataineh MT, Künstner A, Dash NR, Alsafar HS, Ragab M, Schmelter F, Sina C, Busch H, Ibrahim SM (2023) Uncovering the relationship between gut microbial dysbiosis, metabolomics, and dietary intake in type 2 diabetes mellitus and in healthy volunteers: a multi-omics analysis. Sci Rep 13(1):17943

Article  CAS  PubMed  PubMed Central  Google Scholar 

Allen CL, Bayraktutan U (2009) Oxidative stress and its role in the pathogenesis of ischaemic stroke. Int J Stroke 4(6):461–470. https://doi.org/10.1111/j.1747-4949.2009.00387

Article  CAS  PubMed  Google Scholar 

Asada Y, Yamashita A, Sato Y, Hatakeyama K (2020) Pathophysiology of atherothrombosis: mechanisms of thrombus formation on disrupted atherosclerotic plaques. Pathol Int 70(6):309–322. https://doi.org/10.1111/pin.12921

Article  PubMed  PubMed Central  Google Scholar 

Asano T, Tateishi NN, Matsui T, Mori T, Kagamiishi Y, Sato S, Katsube N (2003) Functional modulation of astrocytes by a novel agent ONO-2506 mitigates delayed infarct expansion with a wide therapeutic time window, inducing prompt neurological recovery through reduction of the extracellular level of glutamate. Int Congr Ser 1252:147–151. https://doi.org/10.1016/S0531-5131(03)00028-1

Article  CAS  Google Scholar 

Asarcikli LD, Kafes H, Sen T, Ipek EG, Beton O, Temizhan A, Yilmaz MB (2022) Which is the best for the warfarin monitoring: following up by fixed or variable physician? North Clin Istanbul. https://doi.org/10.14744/nci.2021.06981

Article  Google Scholar 

Ballou S, Keefer L (2017) The impact of irritable bowel syndrome on daily functioning: characterizing and understanding daily consequences of IBS. Neurogastroenterology Motil 29(4):12982. https://doi.org/10.1111/nmo.12982

Article  Google Scholar 

Bejček J, Spiwok V, Kmoníčková E, Rimpelová S (2021) Na+/K+-ATPase revisited: on its mechanism of action, role in cancer, and activity modulation. Molecules 26(7):1905. https://doi.org/10.3390/molecules26071905

Article  CAS  PubMed  PubMed Central  Google Scholar 

Belov KD, Kriska J, Tureckova J, Anderova M (2020) Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells. Front Cell Neurosci 14:51

Article  Google Scholar 

Benakis C, Brea D, Caballero S, Faraco G, Moore J, Murphy M, Sita G, Racchumi G, Ling L, Pamer EG, Iadecola C (2016) Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells. Nat Med 22(5):516–523

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boehme AK, Esenwa C, Elkind MS (2017) Stroke risk factors, genetics, and prevention. Circul Res 120(3):472–495. https://doi.org/10.1161/CIRCRESAHA.116.308398

Article  CAS  Google Scholar 

Candelli M, Franza L, Pignataro G, Ojetti V, Covino M, Piccioni A, Gasbarrini A, Franceschi F (2021) Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases. Int J Mol Sci 22(12):6242. https://doi.org/10.3390/ijms22126242

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cekanaviciute E, Buckwalter MS (2016) Astrocytes: integrative regulators of neuroinflammation in stroke and other neurological diseases. Neurotherapeutics 13(4):685–701. https://doi.org/10.1007/s13311-016-0477-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chang Y, Woo HG, Jeong JH, Kim GH, Park KD, Song TJ (2021) Microbiota dysbiosis and functional outcome in acute ischemic stroke patients. Sci Rep 11(1):10977

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen R, Xu Y, Wu P, Zhou H, Lasanajak Y, Fang Y, Tang L, Ye L, Li X, Cai Z, Zhao J (2019) Transplantation of fecal microbiota rich in short chain fatty acids and butyric acid treat cerebral ischemic stroke by regulating gut microbiota. Pharmacol Res 148:104403. https://doi.org/10.1016/j.phrs.2019.104403

Article  CAS  PubMed  Google Scholar 

Chen S, Xu P, Fang Y, Lenahan C (2020) The updated role of the blood brain barrier in subarachnoid hemorrhage: from basic and clinical studies. Curr Neuropharmacol 18(12):1266–1278. https://doi.org/10.2174/1570159X18666200914161231

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen G, Shi F, Yin W, Guo Y, Liu A, Shuai J, Sun J (2022) Gut microbiota dysbiosis: the potential mechanisms by which alcohol disrupts gut and brain functions. Front Microbiol 13:916765. https://doi.org/10.3389/fmicb.2022.916765

Article  PubMed  PubMed Central  Google Scholar 

Chen G, Du X, Cui J, Song J, Xiong M, Zeng X, Yang H, Xu K (2024) Role of gut microbiota in ischemic stroke: a narrative review of human and animal studies. Neuroprotection. https://doi.org/10.1002/nep3.44

Article  Google Scholar 

Cheon GJ, Kang SY, Rahim MK, Kim YI, Kang HJ, Shin HY, Kang KW, Chung JK, Kim EE, Lee DS (2017) Clinical significance of pretreatment FDG PET/CT in MIBG-avid pediatric neuroblastoma. Nuclear Med Mol Imaging 51:154–160

Article  Google Scholar 

Daffertshofer M, Gass A, Ringleb P, Sitzer M, Sliwka U, Els T, Sedlaczek O, Koroshetz WJ, Hennerici MG (2005) Transcranial low-frequency ultrasound-mediated thrombolysis in brain ischemia: increased risk of haemorrhage with combined ultrasound and tissue plasminogen activator: results of a phase II clinical trial. Stroke 36(7):1441–1446. https://doi.org/10.1161/01.STR.0000170707.86793.1a

Article  PubMed  Google Scholar 

Dehghani F, Abdollahi S, Shidfar F, Clark CC, Soltani S (2023) Probiotics supplementation and brain-derived neurotrophic factor (BDNF): a systematic review and meta-analysis of randomized controlled trials. Nutr Neurosci 26(10):942–952. https://doi.org/10.1080/1028415X.2022.2110664

Article  PubMed  Google Scholar 

Delpont B, Blanc C, Osseby GV, Hervieu-Bègue M, Giroud M, Béjot Y (2018) Pain after stroke: a review. Rev Neurol 174(10):671–674. https://doi.org/10.1016/j.neurol.2017.11.011

Article  CAS  PubMed  Google Scholar 

Dimidi E, Christodoulides S, Scott SM, Whelan K (2017) Mechanisms of action of probiotics and the gastrointestinal microbiota on gut motility and constipation. Adv Nutr 8(3):484–494. https://doi.org/10.3945/an.116.014407

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dinan TG, Cryan JF (2017) Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. J Physiol 595(2):489–503. https://doi.org/10.1113/JP273106

Article  CAS  PubMed  Google Scholar 

Dong R, Huang R, Wang J, Liu H, Xu Z (2021) Effects of microglial activation and polarization on brain injury after stroke. Front Neurol 12:620948. https://doi.org/10.3389/fneur.2021.620948

Article  PubMed  PubMed Central  Google Scholar 

Doyle KP, Cekanaviciute E, Mamer LE, Buckwalter MS (2010) TGFβ signalling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke. J Neuroinflamm 7:1–13

Article  Google Scholar 

Duan J, Gao S, Tu S, Lenahan C, Shao A, Sheng J (2021) Pathophysiology and therapeutic potential of NADPH oxidases in ischemic stroke-induced oxidative stress. Oxidative Med Cell Longev 2021(1):6631805. https://doi.org/10.1155/2021/6631805

Article  CAS  Google Scholar 

Duan T, Du Y, Xing C, Wang HY, Wang RF (2022) Toll-like receptor signalling and its role in cell-mediated immunity. Front Immunol 13:812774. https://doi.org/10.3389/fimmu.2022.812774

Article  CAS  PubMed  PubMed Central