Abulseoud OA, Karpyak VM, Schneekloth T, Hall-Flavin DK, Loukianova LL, Geske JR, Biernacka JM, Mrazek DA, Frye MA (2013) A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence. Am J Addict 22:437–442. https://doi.org/10.1111/j.1521-0391.2013.12021.x

Article  PubMed  PubMed Central  Google Scholar 

Albrechet-Souza L, Schratz CL, Gilpin NW (2020) Sex differences in traumatic stress reactivity in rats with and without a history of alcohol drinking. Biol Sex Differ 11:27. https://doi.org/10.1186/s13293-020-00303-w

Article  CAS  PubMed  PubMed Central  Google Scholar 

Albrechet-Souza L, Kasten CR, Bertagna NB, Wills TA (2024) Sex-specific negative affect-like behaviour and parabrachial nucleus activation induced by BNST stimulation in adult mice with adolescent alcohol history. Addict Biol 29:e13366. https://doi.org/10.1111/adb.13366

Article  CAS  PubMed  PubMed Central  Google Scholar 

Asok A, Schulkin J, Rosen JB (2016) Corticotropin releasing factor type-1 receptor antagonism in the dorsolateral bed nucleus of the stria terminalis disrupts contextually conditioned fear, but not unconditioned fear to a predator odor. Psychoneuroendocrinology 70:17–24. https://doi.org/10.1016/j.psyneuen.2016.04.021

Article  CAS  PubMed  PubMed Central  Google Scholar 

Back SE, Payne RL, Wahlquist AH, Carter RE, Stroud Z, Haynes L, Hillhouse M, Brady KT, Ling W (2011) Comparative profiles of men and women with opioid dependence: results from a national multisite effectiveness trial. Am J Drug Alcohol Abuse 37:313–323. https://doi.org/10.3109/00952990.2011.596982

Article  PubMed  PubMed Central  Google Scholar 

Bale TL, Vale WW (2004) CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 44:525–557. https://doi.org/10.1146/annurev.pharmtox.44.101802.121410

Article  CAS  PubMed  Google Scholar 

Bangasser DA (2013) Sex differences in stress-related receptors: ″micro″ differences with ″macro″ implications for mood and anxiety disorders. Biol Sex Differ 4:2. https://doi.org/10.1186/2042-6410-4-2

Article  PubMed  PubMed Central  Google Scholar 

Bertagna NB, Wilson L, Bailey CK, Cruz FC, Albrechet-Souza L, Wills TA (2024) Long-lasting mechanical hypersensitivity and CRF receptor type-1 neuron activation in the BNST following adolescent ethanol exposure. Alcohol Clin Exp Res (Hoboken) 48:48–57. https://doi.org/10.1111/acer.15228

Article  CAS  PubMed  Google Scholar 

Brandner AJ, Baratta AM, Rathod RS, Ferguson C, Taylor BK, Farris SP (2023) Mechanical and heat hyperalgesia upon withdrawal from chronic intermittent ethanol vapor depends on sex, exposure duration, and blood alcohol concentration in mice. J Pain 24:1262–1274. https://doi.org/10.1016/j.jpain.2023.02.024

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brennan PL, Schutte KK, Moos RH (2005) Pain and use of alcohol to manage pain: prevalence and 3-year outcomes among older problem and non-problem drinkers. Addiction 100:777–786. https://doi.org/10.1111/j.1360-0443.2005.01074.x

Article  PubMed  Google Scholar 

Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL (1994) Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53:55–63. https://doi.org/10.1016/0165-0270(94)90144-9

Article  CAS  PubMed  Google Scholar 

Conway KP, Compton W, Stinson FS, Grant BF (2006) Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the national epidemiologic survey on Alcohol and related conditions. J Clin Psychiatry 67:247–257. https://doi.org/10.4088/jcp.v67n0211

Article  CAS  PubMed  Google Scholar 

Dong HW, Petrovich GD, Swanson LW (2001) Topography of projections from amygdala to bed nuclei of the stria terminalis. Brain Res Brain Res Rev 38:192–246. https://doi.org/10.1016/s0165-0173(01)00079-0

Article  CAS  PubMed  Google Scholar 

Egli M, Koob GF, Edwards S (2012) Alcohol dependence as a chronic pain disorder. Neurosci Biobehav Rev 36:2179–2192. https://doi.org/10.1016/j.neubiorev.2012.07.010

Article  PubMed  PubMed Central  Google Scholar 

Fox HC, Sinha R (2009) Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. Harv Rev Psychiatry 17:103–119. https://doi.org/10.1080/10673220902899680

Article  PubMed  PubMed Central  Google Scholar 

Grant BF, Dawson DA (1997) Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J Subst Abuse 9:103–110. https://doi.org/10.1016/s0899-3289(97)90009-2

Article  CAS  PubMed  Google Scholar 

Ide S, Hara T, Ohno A, Tamano R, Koseki K, Naka T, Maruyama C, Kaneda K, Yoshioka M, Minami M (2013) Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats. J Neurosci 33:5881–5894. https://doi.org/10.1523/JNEUROSCI.4278-12.2013

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kaneko T, Kaneda K, Ohno A, Takahashi D, Hara T, Amano T, Ide S, Yoshioka M, Minami M (2016) Activation of adenylate cyclase-cyclic AMP-protein kinase A signaling by corticotropin-releasing factor within the dorsolateral bed nucleus of the stria terminalis is involved in pain-induced aversion. Eur J Neurosci 44:2914–2924. https://doi.org/10.1111/ejn.13419

Article  PubMed  Google Scholar 

Kasten CR, Carzoli KL, Sharfman NM, Henderson T, Holmgren EB, Lerner MR, Miller MC, Wills TA (2020) Adolescent alcohol exposure produces sex differences in negative affect-like behavior and group I mGluR BNST plasticity. Neuropsychopharmacology 45:1306–1315. https://doi.org/10.1038/s41386-020-0670-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kasten CR, Holmgren EB, Lerner MR, Wills TA (2021) BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress. Transl Psychiatry 11:178. https://doi.org/10.1038/s41398-021-01285-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE (2005) Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62(6):617–627. https://doi.org/10.1001/archpsyc.62.6.617

Article  PubMed  PubMed Central  Google Scholar 

Koob GF (2020) Neurobiology of opioid addiction: opponent process, Hyperkatifeia, and negative reinforcement. Biol Psychiatry 87:44–53. https://doi.org/10.1016/j.biopsych.2019.05.023

Article  CAS  PubMed  Google Scholar 

Koob GF (2021) Drug addiction: Hyperkatifeia/Negative reinforcement as a Framework for Medications Development. Pharmacol Rev 73:163–201. https://doi.org/10.1124/pharmrev.120.000083

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koob GF, Le Moal M (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24:97–129. https://doi.org/10.1016/S0893-133X(00)00195-0

Article  CAS  PubMed  Google Scholar 

Koob GF, Le Moal M (2005) Neurobiology of addiction. Cambridge, Academic Press

Koob GF, Volkow ND (2016) Neurobiology of addiction: a neurocircuitry analysis. Lancet Psychiatry 3:760–773. https://doi.org/10.1016/S2215-0366(16)00104-8

Article  PubMed  PubMed Central  Google Scholar 

Kudielka BM, Kirschbaum C (2005) Sex differences in HPA axis responses to stress: a review. Biol Psychol 69:113–132. https://doi.org/10.1016/j.biopsycho.2004.11.009

Article  PubMed  Google Scholar 

Kwako LE, Spagnolo PA, Schwandt ML, Th