Argaman Y, Kisler LB, Granovsky Y, Coghill RC, Sprecher E, Manor D, Weissman-Fogel I (2020) The endogenous analgesia signature in the resting brain of healthy adults and migraineurs. J Pain 21(7–8):905–918

Article  CAS  PubMed  Google Scholar 

Ashina M, Terwindt GM, Al-Karagholi MA, de Boer I, Lee MJ, Hay DL, Schulte LH, Hadjikhani N, Sinclair AJ, Ashina H, Schwedt TJ, Goadsby PJ (2021) Migraine: disease characterisation, biomarkers, and precision medicine. Lancet 397(10283):1496–1504

Article  CAS  PubMed  Google Scholar 

Ashina S, Melo-Carrillo A, Szabo E, Borsook D, Burstein R (2023) Pre-treatment non-ictal cephalic allodynia identifies responders to prophylactic treatment of chronic and episodic migraine patients with galcanezumab: a prospective quantitative sensory testing study (NCT04271202). Cephalalgia 43(3):3331024221147881

Article  PubMed  Google Scholar 

Ashina S, Terwindt GM, Steiner TJ, Lee MJ, Porreca F, Tassorelli C, Schwedt TJ, Jensen RH, Diener HC, Lipton RB (2023) Medication overuse headache. Nat Rev Dis Primers 9(1):5

Article  PubMed  Google Scholar 

Barone M, Imaz F, De la Torre Canales G, Venosta M, Dri J, Intelangelo L (2024) Somatosensory and psychosocial profile of migraine patients: a cross-sectional study. Musculoskelet Sci Pract 70:102924

Article  PubMed  Google Scholar 

Brines M, Culver DA, Ferdousi M, Tannemaat MR, van Velzen M, Dahan A, Malik RA (2018) Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy. Sci Rep 8(1):4734

Article  PubMed  PubMed Central  Google Scholar 

Burstein R, Jakubowski M, Garcia-Nicas E, Kainz V, Bajwa Z, Hargreaves R, Becerra L, Borsook D (2010) Thalamic sensitization transforms localized pain into widespread allodynia. Ann Neurol 68(1):81–91

Article  PubMed  PubMed Central  Google Scholar 

Choi JY, Oh K, Kim BJ, Chung CS, Koh SB, Park KW (2009) Usefulness of a photophobia questionnaire in patients with migraine. Cephalalgia 29(9):953–959

Article  PubMed  Google Scholar 

De Icco R, Fiamingo G, Greco R, Bottiroli S, Demartini C, Zanaboni AM, Allena M, Guaschino E, Martinelli D, Putortì A, Grillo V, Sances G, Tassorelli C (2020) Neurophysiological and biomolecular effects of erenumab in chronic migraine: an open label study. Cephalalgia 40(12):1336–1345

Article  PubMed  Google Scholar 

De Icco R, Perrotta A, Grillo V, Cosentino G, Sances G, Sandrini G, Tassorelli C (2020) Experimentally induced spinal nociceptive sensitization increases with migraine frequency: a single-blind controlled study. Pain 161(2):429–438

Article  PubMed  Google Scholar 

de la Coba P, Bruehl S, Del Paso GAR (2021) Slowly repeated evoked pain (SREP) as a central sensitization marker in episodic migraine patients. Sci Rep 11(1):4582

Article  PubMed  PubMed Central  Google Scholar 

de Tommaso M, Losito L, Difruscolo O, Sardaro M, Libro G, Guido M, Lamberti P, Livrea P (2005) Capsaicin failed in suppressing cortical processing of CO2 laser pain in migraine patients. Neurosci Lett 384(1–2):150–155

Article  PubMed  Google Scholar 

de Tommaso M, Sardaro M, Pecoraro C, Di Fruscolo O, Serpino C, Lamberti P, Livrea P (2007) Effects of the remote C fibres stimulation induced by capsaicin on the blink reflex in chronic migraine. Cephalalgia 27(8):881–890

Article  PubMed  Google Scholar 

de Tommaso M, Baumgartner U, Sardaro M, Difruscolo O, Serpino C, Treede RD (2008) Effects of distraction versus spatial discrimination on laser-evoked potentials in migraine. Headache 48(3):408–416

Article  PubMed  Google Scholar 

Di Antonio S, Arendt-Nielsen L, Ponzano M, Bovis F, Torelli P, Finocchi C, Castaldo M Trigeminocervical pain sensitivity during the migraine cycle depends on headache frequency. Neurol Sci 2023:1–12

Elizagaray-Garcia I, Carvalho GF, Szikszay TM, Adamczyk WM, Navarro-Fernandez G, Alvarez-Testillano P, Diaz-de-Teran J, Luedtke K, Gil-Martinez A (2022) Psychophysical testing in chronic migraine and chronic tension type headache: an observational study. Cephalalgia 42(7):618–630

Article  PubMed  Google Scholar 

Gazerani P, Fuglsang R, Pedersen JG, Sørensen J, Kjeldsen JL, Yassin H, Nedergaard BS (2019) A randomized, double-blinded, placebo-controlled, parallel trial of vitamin D(3) supplementation in adult patients with migraine. Curr Med Res Opin 35(4):715–723

Article  CAS  PubMed  Google Scholar 

Granovsky Y, Shor M, Shifrin A, Sprecher E, Yarnitsky D, Bar-Shalita T (2018) Assessment of responsiveness to Everyday Non-noxious Stimuli in Pain-Free Migraineurs with Versus without Aura. J Pain 19(8):943–951

Article  PubMed  Google Scholar 

Guldiken YC, Petropoulos IN, Malik A, Malik RA, Yüksel R, Budak F, Selekler HM (2023) Corneal confocal microscopy identifies corneal nerve fiber loss in patients with migraine. Cephalalgia 43(5):3331024231170810

Article  PubMed  Google Scholar 

Guy N, Voisin D, Mulliez A, Clavelou P, Dallel R (2018) Medication overuse reinstates conditioned pain modulation in women with migraine. Cephalalgia 38(6):1148–1158

Article  PubMed  Google Scholar 

Headache_Classification_Committee_of_the_International_Headache_Society (2018); 38(1):1-211

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane 2023

Kennedy DL, Kemp HI, Ridout D, Yarnitsky D, Rice ASC (2016) Reliability of conditioned pain modulation: a systematic review. Pain 157(11):2410–2419

Article  PubMed  PubMed Central  Google Scholar 

Kinard KI, Smith AG, Singleton JR, Lessard MK, Katz BJ, Warner JE, Crum AV, Mifflin MD, Brennan KC, Digre KB (2015) Chronic migraine is associated with reduced corneal nerve fiber density and symptoms of dry eye. Headache 55(4):543–549

Article  PubMed  PubMed Central  Google Scholar 

King CD, Wong F, Currie T, Mauderli AP, Fillingim RB, Riley JL 3 (2009) Deficiency in endogenous modulation of prolonged heat pain in patients with irritable bowel syndrome and temporomandibular disorder. Pain 143(3):172–178

Kisler LB, Granovsky Y, Coghill RC, Sprecher E, Manor D, Yarnitsky D, Weissman-Fogel I (2018) Do patients with interictal migraine modulate pain differently from healthy controls? A psychophysical and brain imaging study. Pain 159(12):2667–2677

Article  PubMed  Google Scholar 

Kisler LB, Weissman-Fogel I, Coghill RC, Sprecher E, Yarnitsky D, Granovsky Y (2019) Individualization of Migraine Prevention: a randomized controlled trial of psychophysical-based prediction of Duloxetine Efficacy. Clin J Pain 35(9):753–765

Article  PubMed  Google Scholar 

Kroll LS, Hammarlund CS, Gard G, Jensen RH, Bendtsen L (2018) Has aerobic exercise effect on pain perception in persons with migraine and coexisting tension-type headache and neck pain? A randomized, controlled, clinical trial. Eur J Pain 22(8):1399–1408

Article  Google Scholar 

Lutolf R, Rosner J, Curt A, Hubli M (2022) Indicators of central sensitization in chronic neuropathic pain after spinal cord injury. Eur J Pain 26(10):2162–2175

Article  PubMed  PubMed Central  Google Scholar 

Malo-Urriés M, Estébanez-de-Miguel E, Bueno-Gracia E, Tricás-Moreno JM, Santos-Lasaosa S, Hidalgo-García C (2020) Sensory function in headache: a comparative study among patients with cluster headache, migraine, tension-type headache, and asymptomatic subjects. Neurol Sci 41(10):2801–2810

Article  PubMed  Google Scholar 

McGuinness LA, Higgins JPT (2021) Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods 12(1):55–61

Article  PubMed  Google Scholar 

Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8(5):336–341

Article  PubMed  Google Scholar 

Nahman-Averbuch H, Granovsky Y, Coghill RC, Yarnitsky D, Sprecher E, Weissman-Fogel I (2013) Waning of conditioned pain modulation: a novel expression of subtle pronociception in migraine. Headache 53(7):1104–1115

Article  PubMed  Google Scholar 

Nahman-Averbuch H, Shefi T, Schneider VJ 2nd, Li D, Ding L, King CD, Coghill RC (2018) Quantitative sensory testing in patients with migraine: a systematic review and meta-analysis. Pain 159(7):1202–1223

Nahman-Averbuch H, Schneider VJ 2nd, Chamberlin LA, Van Kroon AM, Peugh JL, Lee GR, Radhakrishnan R, Hershey AD, Powers SW, Coghill RC, King CD (2021) Identification of neural and psychophysical predictors of headache reduction after cognitive behavioral therapy in adolescents with migraine. Pain 162(2):372–381

Neziri AY, Haesler S, Petersen-Felix S, Muller M, Arendt-Nielsen L, Manresa JB, Andersen OK, Curatolo M (2010) Generalized expansion of nociceptive reflex receptive fields in chronic pain patients. Pain 151(3):798–805

Article  PubMed  Google Scholar 

Niesters M, Proto PL, Aarts L, Sarton EY, Drewes AM, Dahan A (2014) Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy. Br J Anaesth 113(1):148–156

Article  CAS  PubMed