Exosomes and solid cancer therapy: where are we now?

Kim TK, Vandsemb EN, Herbst RS, Chen L. Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunities. Nat Rev Drug Discov. 2022;21(7):529–40. https://doi.org/10.1038/s41573-022-00493-5.

Article  CAS  PubMed  Google Scholar 

Mellman I, Chen DS, Powles T, Turley SJ. The cancer-immunity cycle: Indication, genotype, and immunotype. Immunity. 2023;56(10):2188–205. https://doi.org/10.1016/j.immuni.2023.09.011.

Article  CAS  PubMed  Google Scholar 

Clancy JW, D’Souza-Schorey C. Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment. Annu Rev Pathol. 2023;24(18):205–29. https://doi.org/10.1146/annurev-pathmechdis-031521-022116.

Article  CAS  Google Scholar 

Han QF, Li WJ, Hu KS, Gao J, Zhai WL, Yang JH, Zhang SJ. Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer. Mol Cancer. 2022;21(1):207. https://doi.org/10.1186/s12943-022-01671-0.

Article  PubMed  PubMed Central  Google Scholar 

Wan Z, Dong Y, Wei M, Gao X, Yang G, Zhang J, Liu L. Exosomes in tumor immunotherapy: mediator, drug carrier, and prognostic biomarker. Adv Biosyst. 2020;4(11):e2000061. https://doi.org/10.1002/adbi.202000061.

Article  PubMed  Google Scholar 

Welsh JA, Goberdhan DCI, O’Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku’ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW (2024) Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles 13(2):e12404. https://doi.org/10.1002/jev2.12404 Erratum in: J Extracell Vesicles. 2024;13(5):e12451. https://doi.org/10.1002/jev2.12451

Arya SB, Collie SP, Parent CA. The ins-and-outs of exosome biogenesis, secretion, and internalization. Trends Cell Biol. 2024;34(2):90–108. https://doi.org/10.1016/j.tcb.2023.06.006.

Article  CAS  PubMed  Google Scholar 

Zuo B, Zhang Y, Zhao K, Wu L, Qi H, Yang R, Gao X, Geng M, Wu Y, Jing R, Zhou Q, Seow Y, Yin H. Universal immunotherapeutic strategy for hepatocellular carcinoma with exosome vaccines that engage adaptive and innate immune responses. J Hematol Oncol. 2022;15(1):46. https://doi.org/10.1186/s13045-022-01266-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang L, Rong Y, Tang X, Yi K, Qi P, Hou J, Liu W, He Y, Gao X, Yuan C, Wang F. Engineered exosomes as an in situ DC-primed vaccine to boost antitumor immunity in breast cancer. Mol Cancer. 2022;21(1):45. https://doi.org/10.1186/s12943-022-01515-x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Whiteside TL. Exosome and mesenchymal stem cell cross-talk in the tumor microenvironment. Semin Immunol. 2018;35:69–79. https://doi.org/10.1016/j.smim.2017.12.00.

Article  CAS  PubMed  Google Scholar 

Zhang Q, Xiao Q, Yin H, Xia C, Pu Y, He Z, Hu Q, Wang J, Wang Y. Milk-exosome based pH/light sensitive drug system to enhance anticancer activity against oral squamous cell carcinoma. RSC Adv. 2020;10(47):28314–23. https://doi.org/10.1039/d0ra05630h.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang B, Zhuang X, Deng ZB, Jiang H, Mu J, Wang Q, Xiang X, Guo H, Zhang L, Dryden G, Yan J, Miller D, Zhang HG. Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit. Mol Ther. 2014;22(3):522–34. https://doi.org/10.1038/mt.2013.190.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sriwastva MK, Deng ZB, Wang B, Teng Y, Kumar A, Sundaram K, Mu J, Lei C, Dryden GW, Xu F, Zhang L, Yan J, Zhang X, Park JW, Merchant ML, Egilmez NK, Zhang HG. Exosome-like nanoparticles from Mulberry bark prevent DSS-induced colitis via the AhR/COPS8 pathway. EMBO Rep. 2022;23(3):e53365. https://doi.org/10.15252/embr.202153365.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie S, Zhang Q, Jiang L. Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications. Membranes (Basel). 2022;12(5):498. https://doi.org/10.3390/membranes12050498.

Article  CAS  PubMed  Google Scholar 

Kim HI, Park J, Zhu Y, Wang X, Han Y, Zhang D. Recent advances in extracellular vesicles for therapeutic cargo delivery. Exp Mol Med. 2024;56(4):836–49. https://doi.org/10.1038/s12276-024-01201-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tian T, Zhu YL, Zhou YY, Liang GF, Wang YY, Hu FH, Xiao ZD. Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery. J Biol Chem. 2014;289(32):22258–67. https://doi.org/10.1074/jbc.M114.588046.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nolte-’t Hoen E, Cremer T, Gallo RC, Margolis LB. Extracellular vesicles and viruses: are they close relatives? Proc Natl Acad Sci U S A. 2016;113(33):9155–61. https://doi.org/10.1073/pnas.1605146113.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles. 2014;4:3. https://doi.org/10.3402/jev.v3.24641.

Article  CAS  Google Scholar 

Joshi BS, de Beer MA, Giepmans BNG, Zuhorn IS. Endocytosis of extracellular vesicles and release of their cargo from endosomes. ACS Nano. 2020;14(4):4444–55. https://doi.org/10.1021/acsnano.9b10033.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Polanco JC, Hand GR, Briner A, Li C, Götz J. Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathol. 2021;141(2):235–56. https://doi.org/10.1007/s00401-020-02254-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hazawa M, Tomiyama K, Saotome-Nakamura A, Obara C, Yasuda T, Gotoh T, Tanaka I, Yakumaru H, Ishihara H, Tajima K. Radiation increases the cellular uptake of exosomes through CD29/CD81 complex formation. Biochem Biophys Res Commun. 2014;446(4):1165–71. https://doi.org/10.1016/j.bbrc.2014.03.067.

Article  CAS  PubMed  Google Scholar 

Prada I, Meldolesi J. Binding and fusion of extracellular vesicles to the plasma membrane of their cell targets. Int J Mol Sci. 2016;17(8):1296. https://doi.org/10.3390/ijms17081296.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Purushothaman A, Bandari SK, Liu J, Mobley JA, Brown EE, Sanderson RD. Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions. J Biol Chem. 2016;291(4):1652–63. https://doi.org/10.1074/jbc.M115.686295.

Article  CAS  PubMed  Google Scholar 

Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R. Suppression of exosomal PD-L1 induces systemic anti-tumor immunity and memory. Cell. 2019;177(2):414-27.e13. https://doi.org/10.1016/j.cell.2019.02.016.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mack M, Kleinschmidt A, Brühl H, Klier C, Nelson PJ, Cihak J, Plachý J, Stangassinger M, Erfle V, Schlöndorff D. Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat Med. 2000;6(7):769–75. https://doi.org/10.1038/77498.

Article  CAS  PubMed  Google Scholar 

Korkut C, Li Y, Koles K, Brewer C, Ashley J, Yoshihara M, Budnik V. Regulation of postsynaptic retrograde signaling by presynaptic exosome release. Neuron. 2013;77(6):1039–46. https://doi.org/10.1016/j.neuron.2013.01.013.

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif