Andreazza AC, Cassini C, Rosa AR et al (2007) Serum S100B and antioxidant enzymes in bipolar patients. J Psychiatr Res 41(6):523–529

Article  PubMed  Google Scholar 

Bhatt S, Nagappa AN, Patil CR (2020) Role of oxidative stress in depression. Drug Discov Today 25(7):1270–1276

Article  CAS  PubMed  Google Scholar 

Cavanagh JT, Carson AJ, Sharpe M et al (2003) Psychological autopsy studies of suicide: a systematic review. Psychol Med 33(3):395–405

Article  CAS  PubMed  Google Scholar 

Correia AS, Cardoso A, Vale N (2023) Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity. Antioxidants (Basel) 12(2):470. https://doi.org/10.3390/antiox12020470

Article  CAS  PubMed  Google Scholar 

Das TK, Javadzadeh A, Dey A et al (2019) Antioxidant defense in schizophrenia and bipolar disorder: A meta-analysis of MRS studies of anterior cingulate glutathione. Prog Neuropsychopharmacol Biol Psychiatry 91:94–102

Article  CAS  PubMed  Google Scholar 

Draganov M, Vives-Gilabert Y, de Diego-Adeliño J et al (2020) Glutamatergic and GABA-ergic abnormalities in First-episode depression. A 1-year follow-up 1H-MR spectroscopic study. J Affect Disord 266:572–577

Article  CAS  PubMed  Google Scholar 

Dringen R (2000) Metabolism and functions of glutathione in brain. Prog Neurobiol 62(6):649–671

Article  CAS  PubMed  Google Scholar 

Dwivedi D, Megha K, Mishra R et al (2020) Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Therapeutic Role in Brain Disorders. Neurochem Res 45(7):1461–1480

Article  CAS  PubMed  Google Scholar 

Erritzoe D, Godlewska BR, Rizzo G et al (2023) Brain Serotonin Release Is Reduced in Patients With Depression: A [11C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge. Biol Psychiat 93(12):1089–1098

Article  CAS  PubMed  Google Scholar 

Faulkner P, Paioni SL, Kozhuharova P et al (2021) Relationship between depression, prefrontal creatine and grey matter volume. J Psychopharmacol 35(12):1464–1472

Article  PubMed  PubMed Central  Google Scholar 

Fernández A, Rodriguez-Palancas A, López-Ibor M et al (2005) Increased occipital delta dipole density in major depressive disorder determined by magnetoencephalography. J Psychiatry Neurosci 30(1):17–23

PubMed  PubMed Central  Google Scholar 

Filatova EV, Shadrina MI, Slominsky PA (2021) Major depression: one brain, one disease, one set of intertwined processes. Cells 10(6):1283

Article  CAS  PubMed  PubMed Central  Google Scholar 

Freed RD, Hollenhorst CN, Weiduschat N et al (2017) A pilot study of cortical glutathione in youth with depression. Psychiatry Res Neuroimaging 270:54–60

Article  PubMed  Google Scholar 

Gawryluk JW, Wang JF, Andreazza AC et al (2011) Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. Int J Neuropsychopharmacol 14(1):123–130

Article  CAS  PubMed  Google Scholar 

Godlewska BR, Near J, Cowen PJ (2015) Neurochemistry of major depression: a study using magnetic resonance spectroscopy. Psychopharmacology 232(3):501–507

Article  CAS  PubMed  Google Scholar 

Guan M, Liu X, Guo L et al (2021) Improved Pre-attentive Processing With Occipital rTMS Treatment in Major Depressive Disorder Patients Revealed by MMN. Front Hum Neurosci 15:648816

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hermens DF, Hatton SN, Lee RSC et al (2018) In vivo imaging of oxidative stress and fronto-limbic white matter integrity in young adults with mood disorders. Eur Arch Psychiatry Clin Neurosci 268(2):145–156

Article  PubMed  Google Scholar 

Evaluation IoHMa (2021) Global Health Data Exchange (GHDx). Available at: http://ghdx.healthdata.org/gbd-results-tool?params=gbd-api-2019-permalink/d780dffbe8a381b25e1416884959e88b. Accessed 5 Nov 2024

Kodydková J, Vávrová L, Zeman M et al (2009) Antioxidative enzymes and increased oxidative stress in depressive women. Clin Biochem 42(13–14):1368–1374

Article  PubMed  Google Scholar 

Kurutas EB (2016) The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. Nutr J 15(1):71

Article  PubMed  PubMed Central  Google Scholar 

Ladd ME, Bachert P, Meyerspeer M et al (2018) Pros and cons of ultra-high-field MRI/MRS for human application. Prog Nucl Magn Reson Spectrosc 109:1–50

Article  CAS  PubMed  Google Scholar 

Lapidus KA, Gabbay V, Mao X et al (2014) In vivo (1)H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder. Neurosci Lett 569:74–79

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62(10):e1-34

Article  PubMed  Google Scholar 

Maes M, Mihaylova I, Kubera M et al (2011) Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression. Neuro Endocrinol Lett 32(2):133–140

PubMed  Google Scholar 

Maes M, Fišar Z, Medina M et al (2012) New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates—Nrf2 activators and GSK-3 inhibitors. Inflammopharmacology 20(3):127–150

Article  CAS  PubMed  Google Scholar 

Maller JJ, Thomson RHS, Rosenfeld JV et al (2014) Occipital bending in depression. Brain 137(6):1830–1837

Article  PubMed  Google Scholar 

Merritt K, McCutcheon RA, Aleman A et al (2023) Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis. Mol Psychiatry. https://doi.org/10.1038/s41380-023-01991-7

Article  PubMed  PubMed Central  Google Scholar 

Morris G, Anderson G, Dean O et al (2014) The glutathione system: a new drug target in neuroimmune disorders. Mol Neurobiol 50(3):1059–1084

Article  CAS  PubMed  Google Scholar 

Murray AJ, Humpston CS, Wilson M et al (2024) Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders — A systematic review and Meta-Analysis. Brain Behav Immun 115:3–12

Article  CAS  PubMed  Google Scholar 

Osimo EF, Pillinger T, Rodriguez IM et al (2020) Inflammatory markers in depression: A meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls. Brain Behav Immun 87:901–909

Article  CAS  PubMed  PubMed Central  Google Scholar 

Poljsak B, Šuput D, Milisav I (2013) Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants. Oxid Med Cell Longev 2013:956792

Article  PubMed  PubMed Central  Google Scholar 

Pradhan S, Bonekamp S, Gillen JS et al (2015) Comparison of single voxel brain MRS AT 3T and 7T using 32-channel head coils. Magn Reson Imaging 33(8):1013–1018

Article  PubMed  PubMed Central  Google Scholar