Obesity and overweight fact sheet World Health Organization. [Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight

Brouwers FP, de Boer RA, van der Harst P, Voors AA, Gansevoort RT, Bakker SJ, et al. Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND. Eur Heart J. 2013;34(19):1424–31.

Article  CAS  PubMed  Google Scholar 

Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, et al. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013;6(2):279–86.

Article  PubMed  Google Scholar 

Kitzman DW, Shah SJ. The HFpEF obesity phenotype: the elephant in the room. J Am Coll Cardiol. 2016;68(2):200–3.

Article  PubMed  Google Scholar 

Pandey A, LaMonte M, Klein L, Ayers C, Psaty BM, Eaton CB, et al. Relationship between physical activity, body mass index, and risk of heart failure. J Am Coll Cardiol. 2017;69(9):1129–42.

Article  PubMed  PubMed Central  Google Scholar 

Rao VN, Zhao D, Allison MA, Guallar E, Sharma K, Criqui MH, et al. Adiposity and incident heart failure and its subtypes: MESA (multi-ethnic study of atherosclerosis). JACC Heart Fail. 2018;6(12):999–1007.

Article  PubMed  PubMed Central  Google Scholar 

Haass M, Kitzman DW, Anand IS, Miller A, Zile MR, Massie BM, et al. Body mass index and adverse cardiovascular outcomes in heart failure patients with preserved ejection fraction: results from the Irbesartan in Heart failure with preserved ejection fraction (I-PRESERVE) trial. Circ Heart Fail. 2011;4(3):324–31.

Article  PubMed  PubMed Central  Google Scholar 

Savji N, Meijers WC, Bartz TM, Bhambhani V, Cushman M, Nayor M, et al. The association of obesity and cardiometabolic traits with Incident HFpEF and HFrEF. JACC Heart Fail. 2018;6(8):701–9.

Article  PubMed  PubMed Central  Google Scholar 

Pieske B, Tschope C, de Boer RA, Fraser AG, Anker SD, Donal E, et al. How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur Heart J. 2019;40(40):3297–317.

Article  PubMed  Google Scholar 

Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. A simple, evidence-based approach to help guide diagnosis of heart failure with preserved ejection fraction. Circulation. 2018;138(9):861–70.

Article  PubMed  PubMed Central  Google Scholar 

Mueller C, McDonald K, de Boer RA, Maisel A, Cleland JGF, Kozhuharov N, et al. Heart Failure Association of the European Society of Cardiology practical guidance on the use of natriuretic peptide concentrations. Eur J Heart Fail. 2019;21(6):715–31.

Article  CAS  PubMed  Google Scholar 

Collaboration NCDRF. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants. Lancet. 2016;387(10026):1377–96.

Article  Google Scholar 

Rothman KJ. BMI-related errors in the measurement of obesity. Int J Obes (Lond). 2008;32(Suppl 3):S56–9.

Article  PubMed  Google Scholar 

Berrington de Gonzalez A, Hartge P, Cerhan JR, Flint AJ, Hannan L, MacInnis RJ, et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010;363(23):2211–9.

Article  CAS  PubMed  Google Scholar 

Global BMIMC, Di Angelantonio E, Bhupathiraju Sh N, Wormser D, Gao P, Kaptoge S, et al. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet. 2016;388(10046):776–86.

Article  Google Scholar 

Bosy-Westphal A, Muller MJ. Diagnosis of obesity based on body composition-associated health risks-time for a change in paradigm. Obes Rev. 2021;22(Suppl 2):e13190.

Article  PubMed  Google Scholar 

Srikanthan P, Horwich TB, Tseng CH. Relation of muscle mass and fat mass to cardiovascular disease mortality. Am J Cardiol. 2016;117(8):1355–60.

Article  PubMed  Google Scholar 

Abbasi A, Peelen LM, Corpeleijn E, van der Schouw YT, Stolk RP, Spijkerman AM, et al. Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study. BMJ. 2012;345:e5900.

Article  PubMed  PubMed Central  Google Scholar 

Suthahar N, Wang K, Zwartkruis VW, Bakker SJL, Inzucchi SE, Meems LMG, et al. Associations of relative fat mass, a new index of adiposity, with type-2 diabetes in the general population. Eur J Intern Med. 2023;109:73–8.

Article  PubMed  Google Scholar 

Woolcott OO, Bergman RN. Relative fat mass (RFM) as a new estimator of whole-body fat percentage horizontal line a cross-sectional study in American adult individuals. Sci Rep. 2018;8(1):10980.

Article  PubMed  PubMed Central  Google Scholar 

Krakauer NY, Krakauer JC. A new body shape index predicts mortality hazard independently of body mass index. PLoS ONE. 2012;7(7):e39504.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thomas DM, Bredlau C, Bosy-Westphal A, Mueller M, Shen W, Gallagher D, et al. Relationships between body roundness with body fat and visceral adipose tissue emerging from a new geometrical model. Obes (Silver Spring). 2013;21(11):2264–71.

Article  Google Scholar 

Park Y, Kim NH, Kwon TY, Kim SG. A novel adiposity index as an integrated predictor of cardiometabolic disease morbidity and mortality. Sci Rep. 2018;8(1):16753.

Article  PubMed  PubMed Central  Google Scholar 

Suthahar N, Meems LMG, Withaar C, Gorter TM, Kieneker LM, Gansevoort RT, et al. Relative fat mass, a new index of adiposity, is strongly associated with incident heart failure: data from PREVEND. Sci Rep. 2022;12(1):147.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bernhardt V, Babb TG. Exertional dyspnoea in obesity. Eur Respir Rev. 2016;25(142):487–95.

Article  PubMed  PubMed Central  Google Scholar 

Sin DD, Jones RL, Man SF. Obesity is a risk factor for dyspnea but not for airflow obstruction. Arch Intern Med. 2002;162(13):1477–81.

Article  PubMed  Google Scholar 

Jones RL, Nzekwu MM. The effects of body mass index on lung volumes. Chest. 2006;130(3):827–33.

Article  PubMed  Google Scholar 

Ofir D, Laveneziana P, Webb KA, O’Donnell DE. Ventilatory and perceptual responses to cycle exercise in obese women. J Appl Physiol (1985). 2007;102(6):2217–26.

Article  PubMed  Google Scholar 

Pankow W, Podszus T, Gutheil T, Penzel T, Peter J, Von Wichert P. Expiratory flow limitation and intrinsic positive end-expiratory pressure in obesity. J Appl Physiol (1985). 1998;85(4):1236–43.

Article  CAS  PubMed  Google Scholar 

Naimark A, Cherniack RM. Compliance of the respiratory system and its components in health and obesity. J Appl Physiol. 1960;15:377–82.

Article  CAS  PubMed  Google Scholar 

Sharp JT, Henry JP, Sweany SK, Meadows WR, Pietras RJ. The total work of breathing in normal and obese men. J Clin Invest. 1964;43(4):728–39.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Witte J, Singh H, Turk Y, van Huisstede A, Birnie E, Hiemstra P et al. Effect of bariatric surgery on lung function and asthma control after 8 years of follow-up. Allergy Asthma Proc. 2023;44(3):165– 70.

Wearing SC, Hennig EM, Byrne NM, Steele JR, Hills AP. Musculoskeletal disorders associated with obesity: a biomechanical perspective. Obes Rev. 2006;7(3):239–50.

Article  CAS  PubMed  Google Scholar 

Buckwalter JA, Saltzman C, Brown T. The impact of osteoarthritis: implications for research. Clin Orthop Relat Res. 2004(427 Suppl):S6–15.

Lidgren L. The bone and joint decade and the global economic and healthcare burden of musculoskeletal disease. J Rheumatol Suppl. 2003;67:4–5.

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