Consensus on the key characteristics of metabolism disruptors

Smith, M. T. et al. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Env. Health Perspect. 124, 713–721 (2016).

Article  CAS  Google Scholar 

Guyton, K. Z. et al. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 39, 614–622 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Smith, M. T. et al. The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them. Cancer Epidemiol. Biomark. Prev. 29, 1887–1903 (2020).

Article  CAS  Google Scholar 

Atwood, S. T., Lunn, R. M., Garner, S. C. & Jahnke, G. D. New perspectives for cancer hazard evaluation by the report on carcinogens: a case study using read-across methods in the evaluation of haloacetic acids found as water disinfection by-products. Env. Health Perspect. 127, 125003 (2019).

Article  Google Scholar 

International Agency for Research on Cancer. IARC Monographs on the Identification of Carcinogenic Hazards to Humans: Preamble. IARC monographs.iarc.fr/wp-content/uploads/2019/07/Preamble-2019.pdf (2019).

Reproductive and Cancer Hazard Assessment Branch. Proposition 65: Evidence on the Carcinogenicity of Coumarin. Office of Environmental Health Hazard Assessment oehha.ca.gov/media/downloads/crnr/coumarinhid.pdf (2017).

National Academies of Sciences, Engineering, and Medicine. Using 21st Century Science to Improve Risk-Related Evaluations. NAP nap.nationalacademies.org/read/24635/chapter/1 (2017).

La Merrill, M. A. et al. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat. Rev. Endocrinol. 16, 45–57 (2020).

Article  PubMed  Google Scholar 

Arzuaga, X. et al. Proposed key characteristics of male reproductive toxicants as an approach for organizing and evaluating mechanistic evidence in human health hazard assessments. Env. Health Perspect. 127, 65001 (2019).

Article  Google Scholar 

Luderer, U. et al. Proposed key characteristics of female reproductive toxicants as an approach for organizing and evaluating mechanistic data in hazard assessment. Env. Health Perspect. 127, 75001 (2019).

Article  CAS  Google Scholar 

Rusyn, I. et al. Key characteristics of human hepatotoxicants as a basis for identification and characterization of the causes of liver toxicity. Hepatology 74, 3486–3496 (2021).

Article  CAS  PubMed  Google Scholar 

Lind, L. et al. Key characteristics of cardiovascular toxicants. Env. Health Perspect. 129, 95001 (2021).

Article  CAS  Google Scholar 

Germolec, D. R. et al. Consensus on the key characteristics of immunotoxic agents as a basis for hazard identification. Env. Health Perspect. 130, 105001 (2022).

Article  CAS  Google Scholar 

Heindel, J. J. et al. Obesity II: establishing causal links between chemical exposures and obesity. Biochem. Pharmacol. 199, 115015 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heindel, J. J. et al. Metabolism disrupting chemicals and metabolic disorders. Reprod. Toxicol. 68, 3–33 (2017).

Article  CAS  PubMed  Google Scholar 

Heindel, J. J. et al. Parma consensus statement on metabolic disruptors. Environ. Health 14, 54 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Kouidhi, S. & Clerget-Froidevaux, M. S. Integrating thyroid hormone signaling in hypothalamic control of metabolism: crosstalk between nuclear receptors. Int. J. Mol. Sci. 19, 2017 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Lustig, R. H. et al. Obesity I: overview and molecular and biochemical mechanisms. Biochem. Pharmacol. 199, 115012 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

McIntyre, R. S., Kwan, A. T. H., Rosenblat, J. D., Teopiz, K. M. & Mansur, R. B. Psychotropic drug-related weight gain and its treatment. Am. J. Psychiatry 181, 26–38 (2024).

Article  PubMed  Google Scholar 

Newbold, R. R., Padilla-Banks, E. & Jefferson, W. N. Environmental estrogens and obesity. Mol. Cell. Endocrinol. 304, 84–89 (2009).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Solmi, M. et al. Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects. World Psychiatry 19, 214–232 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Stienstra, R., Tack, C. J., Kanneganti, T. D., Joosten, L. A. & Netea, M. G. The inflammasome puts obesity in the danger zone. Cell Metab. 15, 10–18 (2012).

Article  CAS  PubMed  Google Scholar 

Mantovani, A. Plasma trans-fatty acid and risk of nonalcoholic fatty liver disease: new data from National Health and Nutrition Examination Survey (NHANES). Int. J. Cardiol. 272, 329–330 (2018).

Article  PubMed  Google Scholar 

Eckard, A. R. & McComsey, G. A. Weight gain and integrase inhibitors. Curr. Opin. Infect. Dis. 33, 10–19 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Shang, Q. et al. Serological data analyses show that adenovirus 36 infection is associated with obesity: a meta-analysis involving 5739 subjects. Obesity 22, 895–900 (2014).

Article  PubMed  Google Scholar 

Ogilvie, R. P. & Patel, S. R. The epidemiology of sleep and obesity. Sleep. Health 3, 383–388 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Huang, W., Ramsey, K. M., Marcheva, B. & Bass, J. Circadian rhythms, sleep, and metabolism. J. Clin. Invest. 121, 2133–2141 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Esser, N., Utzschneider, K. M. & Kahn, S. E. Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia. Diabetologia 63, 2007–2021 (2020).

Article  PubMed  Google Scholar 

Bodin, J. et al. Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice. Toxicol. Sci. 137, 311–323 (2014).

Article  CAS  PubMed  Google Scholar 

Bodin, J. et al. Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice. Toxicol. Rep. 2, 99–110 (2015).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sako, Y. & Grill, V. E. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology 127, 1580–1589 (1990).

Article  CAS  PubMed  Google Scholar 

Zhou, Y. P. & Grill, V. E. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J. Clin. Invest. 93, 870–876 (1994).

Article  CAS  PubMed  PubMed Central  Google Scholar 

U.K. Prospective Diabetes Study Group. U.K. prospective diabetes study 16. Overview of 6 years’ therapy of type II diabetes: a progressive disease. Diabetes 44, 1249–1258 (1995).

Article  Google Scholar 

Kahn, S. E. et al. Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT. Diabetes 60, 1552–1560 (2011).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kurita, H. et al. Aryl hydrocarbon receptor-mediated effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on glucose-stimulated insulin secretion in mice. J. Appl. Toxicol. 29, 689–694 (2009).

Article  CAS  PubMed 

留言 (0)

沒有登入
gif