Bonjour P, Clark P, Cooper C, Dawson-Hughes B, De Laet C, Delmas P, et al. WHO scientific group on the assessment of osteoporosis at primary health care level. Summary meeting report. 2004. Brussels, Belgium, 5–7 May 2004.

Van den Bergh JP, van Geel TA, Geusens PP. Osteoporosis, frailty and fracture: implications for case finding and therapy. Nat Rev Rheumatol. 2012;8:163–72.

Article  PubMed  Google Scholar 

Fini M, Salamanna F, Veronesi F, Torricelli P, Nicolini A, Benedicenti S, et al. Role of obesity, alcohol and smoking on bone health. Front Biosci (Elite Ed). 2012;4:2686–706.

Google Scholar 

Engelke K, Gluer CC. Quality and performance measures in bone densitometry. I. Errors and diagnosis. Osteoporos Int. 2006;17:1283–92.

Article  CAS  PubMed  Google Scholar 

Gluer CC, Lu Y, Engelke K. Quality and performance measures in bone densitometry. II. Fracture risk. Osteoporos Int. 2006;17:1449–58.

Article  CAS  PubMed  Google Scholar 

Blake GM, Fogelman I. Role of dual-energy X-ray absorptiometry in the diagnosis and treatment of osteoporosis. J Clin Densitom. 2007;10:102–10.

Article  PubMed  Google Scholar 

Kanis JA, McCloskey EV, Johansson H, Cooper C, Rizzoli R, Reginster JY, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. 2013;24:23–57.

Article  CAS  PubMed  Google Scholar 

Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, et al. National osteoporosis foundation. Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2014;25:2359–81.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lentle B, Cheung AM, Hanley DA, Leslie WD, Lyons D, Papaioannou A, et al. Scientific Advisory Council of Osteoporosis Canada. Osteoporosis Canada 2010 guidelines for the assessment of fracture risk. Can Assoc Radiol J. 2011;62:243–50.

Article  PubMed  PubMed Central  Google Scholar 

Lau EMC, Sambrook P, Seeman E, Leong KH, Leung PC, Delmas P. Guidelines for diagnosing, prevention and treatment of osteoporosis in Asia. APLAR J Rheumatol. 2006;9:24–36.

Article  Google Scholar 

Al-Saleh Y, Sulimani R, Sabico S, Raef H, Fouda M, Alshahrani F, et al. Guidelines for osteoporosis in Saudi Arabia: recommendations from the Saudi Osteoporosis Society. Ann Saudi Med. 2015;35:1–12.

Article  PubMed  PubMed Central  Google Scholar 

Maalouf G, Gannagé-Yared MH, Ezzedine J, Larijani B, Badawi S, Rached A, et al. Middle East and North Africa consensus on osteoporosis. J Musculoskelet Neuronal Interact. 2007;7:131–43.

CAS  PubMed  Google Scholar 

Pecina JL, Romanovsky L, Merry SP, Kennel KA, Thacher TD. Comparison of clinical risk tools for predicting osteoporosis in women ages 50–64. J Am Board Fam Med. 2016;29:233–9.

Article  PubMed  Google Scholar 

Delmas PD, Eastell R, Garnero P, Seibel MJ, Stepan J. The use of biochemical markers of bone turnover in osteoporosis. Committee of Scientific Advisors of the International Osteoporosis Foundation. Osteoporos Int. 2000;11:S2–S17.

Article  PubMed  Google Scholar 

Johnell O, Oden A, De Laet C, Garnero P, Delmas PD, Kanis JA. Biochemical indices of bone turnover and the assessment of fracture probability. Osteoporos Int. 2002;13:523–6.

Article  CAS  PubMed  Google Scholar 

Adami S, Bertoldo F, Brandi ML, Cepollaro C, Filipponi P, Fiore E, et al. Società Italiana dell’Osteoporosi, del Metabolismo Minerale e delle Malattie dello Scheletro. Guidelines for the diagnosis, prevention and treatment of osteoporosis. Reumatismo. 2009;61:260–84.

CAS  PubMed  Google Scholar 

Nordin BE, Morris HA. Osteoporosis and vitamin D. J Cell Biochem. 1992;49:19–25.

Article  CAS  PubMed  Google Scholar 

Richy F, Schacht E, Bruyere O, Ethgen O, Gourlay M, Reginster JY. Vitamin D analogs versus native vitamin D in preventing bone loss and osteoporosis-related fractures: a comparative meta-analysis. Calcif Tissue Int. 2005;76:176–86.

Article  CAS  PubMed  Google Scholar 

Ström O, Borgstrom F, Kanis JA, Compston JE, Cooper C, McCloskey E, et al. Osteoporosis: burden, health care provision and opportunities in the EU. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos. 2011;6:59–155. doi:10.1007/s11657-011-0060-1.

Article  PubMed  Google Scholar 

Weaver CM, Alexander DD, Boushey CJ, Dawson-Hughes B, Lappe JM, LeBoff MS, et al. Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporos Int. 2016;27:367–76.

Article  CAS  PubMed  Google Scholar 

Brannon PM, Yetley EA, Bailey RL, Picciano MF. Vitamin D and health in the 21st century: an update. Am J Clin Nutr. 2008;88:483S–90S.

Article  CAS  PubMed  Google Scholar 

Wöbke TK, Sorg BL, Steinhilber D. Vitamin D in inflammatory diseases. Front Physiol. 2014;5:244.

PubMed  PubMed Central  Google Scholar 

Lagishetty V, Liu NQ, Hewison M. Vitamin D metabolism and innate immunity. Mol Cell Endocrinol. 2011;347:97–105.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mathieu C, Badenhoop K. Vitamin D and type 1 diabetes mellitus: state of the art. Trends Endocrinol Metab. 2005;16:261–6.

Article  CAS  PubMed  Google Scholar 

Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, Gudbjartsson DF, Walters GB, Ingvarsson T, et al. Multiple genetic loci for bone mineral density and fractures. N Engl J Med. 2008;358:2355–65.

Article  CAS  PubMed  Google Scholar 

Holick MF, MacLaughlin JA, Clark MB, Holick SA, Potts JT. Photosynthesis of previtamin D3 in human skin and the physiologic consequences. Science. 1980;210:203–5.

Article  CAS  PubMed  Google Scholar 

Mac Laughlin JA, Anderson RR, Holick MF. Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science. 1982;216:1001–3.

Article  CAS  PubMed  Google Scholar 

Lehmann B, Meurer M. Vitamin D metabolism. Dermatol Ther. 2010;23:2–12.

Article  PubMed  Google Scholar 

Prosser DE, Jones G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem Sci. 2004;29:664–73.

Article  CAS  PubMed  Google Scholar 

Ohyama Y, Yamasaki T. Eight cytochrome P450S catalyze vitamin D metabolism. Front Biosci. 2005;10:608–19.

Google Scholar 

Jones G. Pharmacokinetics of vitamin D toxicity. Am J Clin Nutr. 2008;88:582S–6S.

Article  CAS  PubMed  Google Scholar 

Holick MF. Vitamin D, deficiency. N Engl J Med. 2007;357:266–81.

Article  CAS  PubMed  Google Scholar 

Heaney RP. Assessing vitamin D status. Curr Opin Clin Nutr Metab Care. 2011;14:440–4.

Article  CAS  PubMed  Google Scholar 

Martin A, David V, Quarles LD. Regulation and function of the fgf23/klotho endocrine pathways. Physiol Rev. 2012;92:131–55.

Article  CAS  PubMed  Google Scholar 

Henry HL. The 25(OH)D3/1α,25(OH)2D3-24R-hydroxylase: a catabolic or biosynthetic enzyme? Steroids. 2001;66:391–8.

Article