The PPOS protocol mitigates the detrimental effects of high BMI on embryo and clinical pregnancy outcomes

Rich-Edwards JW, Goldman MB, Willett WC, Hunter DJ, Stampfer MJ, Colditz GA, et al. Adolescent body mass index and infertility caused by ovulatory disorder. Am J Obstet Gynecol. 1994;171(1):171–7.

Article  PubMed  CAS  Google Scholar 

Rich-Edwards JW, Spiegelman D, Garland M, Hertzmark E, Hunter DJ, Colditz GA, et al. Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology. 2002;13(2):184–90.

Article  PubMed  Google Scholar 

Esmaeilzadeh S, Delavar MA, Basirat Z, Shafi H. Physical activity and body mass index among women who have experienced infertility. Arch Med Sci. 2013;9(3):499–505.

Article  PubMed  PubMed Central  Google Scholar 

Rittenberg V, Seshadri S, Sunkara SK, Sobaleva S, Oteng-Ntim E, El-Toukhy T. Effect of body mass index on IVF treatment outcome: an updated systematic review and meta-analysis. Reprod Biomed Online. 2011;23(4):421–39.

Article  PubMed  Google Scholar 

Rittenberg V, Sobaleva S, Ahmad A, Oteng-Ntim E, Bolton V, Khalaf Y, et al. Influence of BMI on risk of miscarriage after single blastocyst transfer. Hum Reprod. 2011;26(10):2642–50.

Article  PubMed  Google Scholar 

McTigue K, Larson JC, Valoski A, Burke G, Kotchen J, Lewis CE, et al. Mortality and cardiac and vascular outcomes in extremely obese women. JAMA. 2006;296(1):79–86.

Article  PubMed  CAS  Google Scholar 

Luke B, Brown MB, Stern JE, Missmer SA, Fujimoto VY, Leach R, et al. Female obesity adversely affects assisted reproductive technology (ART) pregnancy and live birth rates. Hum Reprod. 2011;26(1):245–52.

Article  PubMed  Google Scholar 

Zhang JJ, Feret M, Chang L, Yang M, Merhi Z. Obesity adversely impacts the number and maturity of oocytes in conventional IVF not in minimal stimulation IVF. Gynecol Endocrinol. 2015;31(5):409–13.

Article  PubMed  Google Scholar 

Bellver J, Ayllon Y, Ferrando M, Melo M, Goyri E, Pellicer A, et al. Female obesity impairs in vitro fertilization outcome without affecting embryo quality. Fertil Steril. 2010;93(2):447–54.

Article  PubMed  Google Scholar 

Bellver J, Martinez-Conejero JA, Labarta E, Alama P, Melo MA, Remohi J, et al. Endometrial gene expression in the window of implantation is altered in obese women especially in association with polycystic ovary syndrome. Fertil Steril. 2011;95(7):2335–41. 41 e1-8.

Article  PubMed  CAS  Google Scholar 

Qiu M, Tao Y, Kuang Y, Wang Y. Effect of body mass index on pregnancy outcomes with the freeze-all strategy in women with polycystic ovarian syndrome. Fertil Steril. 2019;112(6):1172–9.

Article  PubMed  CAS  Google Scholar 

Zhang J, Liu H, Mao X, Chen Q, Fan Y, Xiao Y, et al. Effect of body mass index on pregnancy outcomes in a freeze-all policy: an analysis of 22,043 first autologous frozen-thawed embryo transfer cycles in China. BMC Med. 2019;17(1):114.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sermondade N, Huberlant S, Bourhis-Lefebvre V, Arbo E, Gallot V, Colombani M et al. Female obesity is negatively associated with live birth rate following IVF: a systematic review and meta-analysis. (1460–2369 (Electronic)).

Jain A, Polotsky AJ, Rochester D, Berga SL, Loucks T, Zeitlian G, et al. Pulsatile luteinizing hormone amplitude and progesterone metabolite excretion are reduced in obese women. J Clin Endocrinol Metab. 2007;92(7):2468–73.

Article  PubMed  CAS  Google Scholar 

Moragianni VA, Jones SM, Ryley DA. The effect of body mass index on the outcomes of first assisted reproductive technology cycles. Fertil Steril. 2012;98(1):102–8.

Article  PubMed  Google Scholar 

Esinler I, Bozdag G, Esinler D, Lale KS, Yarali H. Luteal-long GnRH agonist versus flexible-multidose GnRH antagonist protocols for overweight and obese patients who underwent ICSI. J Obstet Gynaecol. 2015;35(3):297–301.

Article  PubMed  CAS  Google Scholar 

Wan Q, Qian Y, Xia MJ, Tan L, Lv XY, Meng XQ, et al. Young obese patients may benefit from GnRH-a long protocol contributing to higher implantation rate and live birth rate of fresh IVF-ET cycles. Heliyon. 2023;9(10):e20016.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tu J, Lin G, Lu C, Gong F. A novel modified ultra-long agonist protocol improves the outcome of high body mass index women with polycystic ovary syndrome undergoing IVF/ICSI. Gynecol Endocrinol. 2014;30(3):209–12.

Article  PubMed  Google Scholar 

Kuang Y, Hong Q, Chen Q, Lyu Q, Ai A, Fu Y, et al. Luteal-phase ovarian stimulation is feasible for producing competent oocytes in women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment, with optimal pregnancy outcomes in frozen-thawed embryo transfer cycles. Fertil Steril. 2014;101(1):105–11.

Article  PubMed  CAS  Google Scholar 

Kuang Y, Chen Q, Fu Y, Wang Y, Hong Q, Lyu Q, et al. Medroxyprogesterone acetate is an effective oral alternative for preventing premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation for in vitro fertilization. Fertil Steril. 2015;104(1):62–e703.

Article  PubMed  CAS  Google Scholar 

Massin N. New stimulation regimens: endogenous and exogenous progesterone use to block the LH surge during ovarian stimulation for IVF. Hum Reprod Update. 2017;23(2):211–20.

PubMed  CAS  Google Scholar 

Ata B, Capuzzo M, Turkgeldi E, Yildiz S, La Marca A. Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses. Hum Reprod Update. 2021;27(1):48–66.

Article  PubMed  CAS  Google Scholar 

Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O’Neill CL, et al. Forty years of IVF. Fertil Steril. 2018;110(2):185–324. e5.

Article  PubMed  Google Scholar 

Wang L, Yin M, Liu Y, Chen Q, Wang Y, Ai A, et al. Effect of frozen embryo transfer and progestin-primed ovary stimulation on IVF outcomes in women with high body mass index. Sci Rep. 2017;7(1):7447.

Article  PubMed  PubMed Central  Google Scholar 

Yang Z, Zhao X, Hu X, Ou X, Yin T, Yang J, et al. Body Mass Index showed no impact on the outcome of in Vitro Fertilization in Progestin-primed ovarian stimulation protocol. Evid Based Complement Alternat Med. 2021;2021:9979972.

PubMed  PubMed Central  Google Scholar 

Shen X, Xie Y, Chen D, Guo W, Feng G, Jiang W, et al. Effect of female and male body Mass Index on cumulative live birth rates in the freeze-all strategy. J Clin Endocrinol Metab. 2022;107(4):e1467–76.

Article  PubMed  Google Scholar 

Zhou BF, Cooperative Meta-Analysis Group of the Working Group on Obesity in C. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults–study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Biomed Environ Sci. 2002;15(1):83–96.

PubMed  Google Scholar 

Obesity. preventing and managing the global epidemic. Report of a WHO consultation. (0512–3054 (Print)).

revision Jcfg. 2016 Chinese guidelines for the management of dyslipidemia in adults. (1671–5411 (Print)).

Cummins JM, Breen TM, Harrison KL, Shaw JM, Wilson LM, Hennessey JF. A formula for scoring human embryo growth rates in in vitro fertilization: its value in predicting pregnancy and in comparison with visual estimates of embryo quality. J Vitro Fert Embryo Transf. 1986;3(5):284–95.

Article  CAS  Google Scholar 

Pr-C AL, Arciniegas A, Pr R, Gutierrez H, Toscano RA, Villasenor JL, et al. Iodanthine, a pyrrolizidine alkaloid from senecio iodanthus and senecio bracteatus. J Nat Prod. 1999;62(7):1039–43.

Article  Google Scholar 

Jungheim ES, Schon SB, Schulte MB, DeUgarte DA, Fowler SA, Tuuli MG. IVF outcomes in obese donor oocyte recipients: a systematic review and meta-analysis. Hum Reprod. 2013;28(10):2720–7.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Provost MP, Acharya KS, Acharya CR, Yeh JS, Steward RG, Eaton JL, et al. Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor/recipient cycles from the 2008–2010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry. Fertil Steril. 2016;105(2):364–8.

Article  PubMed  Google Scholar 

Klenov VE, Jungheim ES. Obesity and reproductive function: a review of the evidence. Curr Opin Obstet Gynecol. 2014;26(6):455–60.

Article  PubMed  Google Scholar 

Provost MP, Acharya KS, A

留言 (0)

沒有登入
gif