Cannabidiol (CBD) modulates the transcriptional profile of ethanol-exposed human dermal fibroblast cells

Adamek A, Kasprzak A (2018) Insulin-like growth factor (IGF) system in liver diseases. Int J Mol Sci 19(5):1308. https://doi.org/10.3390/ijms19051308

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alves P, Amaral C, Teixeira N, Correia-da-Silva G (2021) Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts. Arch Toxicol 95:3393–3406. https://doi.org/10.1007/s00204-021-03122-z

Article  CAS  PubMed  Google Scholar 

Anand U, Jones B, Korchev Y, Bloom SR, Pacchetti B, Anand P, Sodergren MH (2020) CBD effects on TRPV1 signaling pathways in cultured DRG neurons. J Pain Res 13:2269–2278. https://doi.org/10.2147/JPR.S258433

Article  CAS  PubMed  PubMed Central  Google Scholar 

Anders S, Pyl PT, Huber W (2015) HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics 31:166–169. https://doi.org/10.1093/bioinformatics/btu638

Article  CAS  PubMed  Google Scholar 

Atalay S, Jarocka-Karpowicz I, Skrzydlewska E (2019) Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants 9(1):21. https://doi.org/10.3390/antiox9010021

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bataller R, Brenner DA (2005) Liver fibrosis. J Clin Invest 115:209–218. https://doi.org/10.1172/JCI24282

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhunia S, Kolishetti N, Arias AY, Vashist A, Nair M (2022) Cannabidiol for neurodegenerative disorders: a comprehensive review. Front Pharmacol 13:989717. https://doi.org/10.3389/fphar.2022.989717

Article  CAS  PubMed  PubMed Central  Google Scholar 

Booz GW (2011) Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med 51:1054–1061. https://doi.org/10.1016/j.freeradbiomed.2011.01.007

Article  CAS  PubMed  PubMed Central  Google Scholar 

Campos AC, Fogaça MV, Sonego AB, Guimarães FS (2016) Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacol Res 112:119–127. https://doi.org/10.1016/j.phrs.2016.01.033

Article  CAS  PubMed  Google Scholar 

Casañas-Sánchez V, Pérez JA, Quinto-Alemany D, Díaz M (2016) Sub-toxic ethanol exposure modulates gene expression and enzyme activity of antioxidant systems to provide neuroprotection in hippocampal HT22 cells. Front Physiol 7:312. https://doi.org/10.3389/fphys.2016.00312

Article  PubMed  PubMed Central  Google Scholar 

Casares L, García V, Garrido-Rodríguez M, Millán E, Collado JA, García-Martín A, Peñarando J, Calzado MA, de la Vega L, Muñoz E (2020) Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol 28:101321. https://doi.org/10.1016/j.redox.2019.101321

Article  CAS  PubMed  Google Scholar 

Cerretani D, Collodel G, Brizzi A, Fiaschi AI, Menchiari A, Moretti E, Moltoni L, Micheli L (2020) Cytotoxic effects of cannabinoids on human HT-29 colorectal adenocarcinoma cells: different mechanisms of THC, CBD, and CB83. Int J Mol Sci 21(15):5533. https://doi.org/10.3390/ijms21155533

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chang Y, Xia L, Song M, Tang M, Patpur BK, Li J, Yang W, Yang C (2020) The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis. Life Sci 251:117595. https://doi.org/10.1016/j.lfs.2020.117595

Article  CAS  PubMed  Google Scholar 

Chen K-A, Farrar MA, Cardamone M, Lawson JA (2018) Cannabis for paediatric epilepsy: challenges and conundrums. Med J Aust 208:132–136. https://doi.org/10.5694/mja17.00699

Article  PubMed  Google Scholar 

Chung Y-H, Huang Y-H, Chu T-H, Chen C-L, Lin P-R, Huang S-C, Wu D-C, Huang C-C, Hu T-H, Kao Y-H, Tai M-H (2018) BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling. Lab Invest 98:999–1013. https://doi.org/10.1038/s41374-018-0069-9

Article  CAS  PubMed  Google Scholar 

Ciftciler R, Ozenirler S, Yucel AA, Cengiz M, Erkan G, Buyukdemirci E, Sönmez C, Esendaglı GY (2017) The importance of serum biglycan levels as a fibrosis marker in patients with chronic hepatitis B. J Clin Lab Anal 31(15):e22109. https://doi.org/10.1002/jcla.22109

Article  CAS  PubMed  Google Scholar 

De Ternay J, Naassila M, Nourredine M, Louvet A, Bailly F, Sescousse G, Maurage P, Cottencin O, Carrieri PM, Rolland B (2019) Therapeutic prospects of cannabidiol for alcohol use disorder and alcohol-related damages on the liver and the brain. Front Pharmacol 10:627. https://doi.org/10.3389/fphar.2019.00627

Article  CAS  PubMed  PubMed Central  Google Scholar 

Del Río C, Ruiz-Pino F, Prados ME, Fiebich BL, Tena-Sempere M, Muñoz E (2022) Cannabidiol markedly alleviates skin and liver fibrosis. Front Pharmacol 13:981817. https://doi.org/10.3389/fphar.2022.981817

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deutsch DG (2016) A personal retrospective: elevating anandamide (AEA) by targeting fatty acid amide hydrolase (FAAH) and the fatty acid binding proteins (FABPs). Front Pharmacol 7:370. https://doi.org/10.3389/fphar.2016.00370

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devinsky O, Cilio MR, Cross H, Fernandez-Ruiz J, French J, Hill C, Katz R, Di Marzo V, Jutras-Aswad D, Notcutt WG, Martinez-Orgado J, Robson PJ, Rohrback BG, Thiele E, Whalley B, Friedman D (2014) Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia 55:791–802. https://doi.org/10.1111/epi.12631

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29:15–21. https://doi.org/10.1093/bioinformatics/bts635

Article  CAS  PubMed  Google Scholar 

Dodt M, Roehr JT, Ahmed R, Dieterich C (2012) FLEXBAR-flexible barcode and adapter processing for next-generation sequencing platforms. Biology 1:895–905. https://doi.org/10.3390/biology1030895

Article  PubMed  PubMed Central  Google Scholar 

Dolganiuc A, Szabo G (2009) In vitro and in vivo models of acute alcohol exposure. World J Gastroenterol 15:1168–1177. https://doi.org/10.3748/wjg.15.1168

Article  PubMed  PubMed Central  Google Scholar 

Fagone P, Mangano K, Mammana S, Pesce A, Pesce A, Caltabiano R, Giorlandino A, Portale TR, Cavalli E, Lombardo GAG, Coco M, Puleo S, Nicoletti F (2015) Identification of novel targets for the diagnosis and treatment of liver fibrosis. Int J Mol Med 36:747–752. https://doi.org/10.3892/ijmm.2015.2264

Article  CAS  PubMed  Google Scholar 

Filev R, Engelke DS, Da Silveira DX, Mello LE, Santos-Junior JG (2017) THC inhibits the expression of ethanol-induced locomotor sensitization in mice. Alcohol 65:31–35. https://doi.org/10.1016/j.alcohol.2017.06.004

Article  CAS  PubMed  Google Scholar 

Gleich T, Spitta G, Butler O, Zacharias K, Aydin S, Sebold M, Garbusow M, Rapp M, Schubert F, Buchert R, Heinz A, Gallinat J (2021) Dopamine D2/3 receptor availability in alcohol use disorder and individuals at high risk: towards a dimensional approach. Addict Biol 26:e12915. https://doi.org/10.1111/adb.12915

Article  CAS  PubMed  Google Scholar 

Gonzalez-Cuevas G, Martin-Fardon R, Kerr TM, Stouffer DG,

留言 (0)

沒有登入
gif