Harnessing the power of exosomes for diagnosis, prognosis, and treatment of hematological malignancies

Karagianni P, Giannouli S, Voulgarelis M. From the (Epi)genome to metabolism and Vice Versa; examples from hematologic malignancy. Int J Mol Sci [Internet]. 2021 22(12).

Juliusson G, Hough R, Leukemia. 2016 [cited 1/19/2024]. In: Tumors in Adolescents and Young Adults [Internet]. S.Karger AG, [cited 1/19/2024]; [0]. Available from: https://doi.org/10.1159/000447076

Damlaj M, El Fakih R, Hashmi SK. Evolution of survivorship in lymphoma, myeloma and leukemia: metamorphosis of the field into long term follow-up care. Blood Rev. 2019;33:63–73.

Article  PubMed  Google Scholar 

Parikh SA. Chronic lymphocytic leukemia treatment algorithm 2018. Blood Cancer J. 2018;8(10):93.

Article  PubMed  PubMed Central  Google Scholar 

Mardani R, Jafari Najaf Abadi MH, Motieian M, Taghizadeh-Boroujeni S, Bayat A, Farsinezhad A, et al. MicroRNA in leukemia: Tumor suppressors and oncogenes with prognostic potential. J Cell Physiol. 2019;234(6):8465–86.

Article  CAS  PubMed  Google Scholar 

Litwińska Z, Łuczkowska K, Machaliński B. Extracellular vesicles in hematological malignancies. Leuk Lymphoma. 2019;60(1):29–36.

Article  PubMed  Google Scholar 

Colombo M, Raposo G, Théry C. Biogenesis, Secretion, and Intercellular Interactions of Exosomes and other Extracellular vesicles. Annu Rev Cell Dev Biol. 2014;30(1):255–89.

Article  CAS  PubMed  Google Scholar 

Théry C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol. 2002;2(8):569–79.

Article  PubMed  Google Scholar 

Bobrie A, Colombo M, Raposo G, Théry C. Exosome Secretion: Molecular mechanisms and roles in Immune responses. Traffic. 2011;12(12):1659–68.

Article  CAS  PubMed  Google Scholar 

Théry C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009;9(8):581–93.

Article  PubMed  Google Scholar 

Wolfers J, Lozier A, Raposo G, Regnault A, Théry C, Masurier C, et al. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med. 2001;7(3):297–303.

Article  CAS  PubMed  Google Scholar 

Dai S, Wan T, Wang B, Zhou X, Xiu F, Chen T, et al. More efficient induction of HLA-A*0201-Restricted and Carcinoembryonic Antigen (CEA)–Specific CTL response by immunization with Exosomes prepared from heat-stressed CEA-Positive tumor cells. Clin Cancer Res. 2005;11(20):7554–63.

Article  CAS  PubMed  Google Scholar 

Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z. Human tumor-derived exosomes selectively impair lymphocyte responses to Interleukin-2. Cancer Res. 2007;67(15):7458–66.

Article  CAS  PubMed  Google Scholar 

Huber V, Fais S, Iero M, Lugini L, Canese P, Squarcina P, et al. Human colorectal Cancer cells induce T-Cell death through release of proapoptotic microvesicles: role in Immune escape. Gastroenterology. 2005;128(7):1796–804.

Article  CAS  PubMed  Google Scholar 

Clayton A, Mitchell JP, Court J, Linnane S, Mason MD, Tabi Z. Human tumor-derived Exosomes Down-Modulate NKG2D Expression1. J Immunol. 2008;180(11):7249–58.

Article  CAS  PubMed  Google Scholar 

Liu C, Yu S, Zinn K, Wang J, Zhang L, Jia Y, et al. Murine mammary carcinoma exosomes promote Tumor Growth by suppression of NK Cell Function1. J Immunol. 2006;176(3):1375–85.

Article  CAS  PubMed  Google Scholar 

Szajnik M, Czystowska M, Szczepanski MJ, Mandapathil M, Whiteside TL. Tumor-Derived microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg). PLoS ONE. 2010;5(7):e11469.

Article  PubMed  PubMed Central  Google Scholar 

Valenti R, Huber V, Filipazzi P, Pilla L, Sovena G, Villa A, et al. Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth Factor-β–Mediated suppressive activity on T lymphocytes. Cancer Res. 2006;66(18):9290–8.

Article  CAS  PubMed  Google Scholar 

Yang C, Yang H, Liu J, Zhu L, Yu S, Zhang X, et al. Focus on exosomes: novel pathogenic components of leukemia. Am J cancer Res. 2019;9(8):1815.

CAS  PubMed  PubMed Central  Google Scholar 

Sato-Kuwabara Y, Melo SA, Soares FA, Calin GA. The fusion of two worlds: non-coding RNAs and extracellular vesicles-diagnostic and therapeutic implications. Int J Oncol. 2015;46(1):17–27.

Article  CAS  PubMed  Google Scholar 

Huan J, Hornick NI, Shurtleff MJ, Skinner AM, Goloviznina NA, Roberts CT Jr, et al. RNA trafficking by acute myelogenous leukemia exosomes. Cancer Res. 2013;73(2):918–29.

Article  CAS  PubMed  Google Scholar 

Garzon R, Pichiorri F, Palumbo T, Visentini M, Aqeilan R, Cimmino A, et al. MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene. 2007;26(28):4148–57.

Article  CAS  PubMed  Google Scholar 

Hatem AS, Ghonaim R, Haggag R. Prognostic impact of microRNAs (miR-155, miR-10a, let-7a) on the outcome of adult patients with Acute myeloid leukemia. Zagazig Univ Med J. 2021;27(5):810–25.

Google Scholar 

Emmrich S, Henke K, Li Z, Schöning J, Schambach A, Reinhardt D, et al. Deciphering the role of Mir-99∼ 125 clusters in the hematopoietic system. Blood. 2011;118(21):213.

Article  Google Scholar 

Zhu Y-D, Wang L, Sun C, Fan L, Zhu D-X, Fang C, et al. Distinctive microRNA signature is associated with the diagnosis and prognosis of acute leukemia. Med Oncol. 2012;29:2323–31.

Article  CAS  PubMed  Google Scholar 

Szczepanek J. Role of microRNA dysregulation in childhood acute leukemias: Diagnostics, monitoring and therapeutics: a comprehensive review. World J Clin Oncol. 2020;11(6):348.

Article  PubMed  PubMed Central  Google Scholar 

Kinjyo I, Bragin D, Grattan R, Winter SS, Wilson BS. Leukemia-derived exosomes and cytokines pave the way for entry into the brain. J Leukoc Biol. 2019;105(4):741–53.

Article  CAS  PubMed  Google Scholar 

Mineo M, Garfield SH, Taverna S, Flugy A, De Leo G, Alessandro R, et al. Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion. Angiogenesis. 2012;15:33–45.

Article  CAS  PubMed  Google Scholar 

Mineo DM, Garfield SH, Alessandro R, Kohn. EC, editors. Exosomes released by K562 chronic myeloid leukemia cells promote endothelial cell tubular differentiation through uptake and cell-to-cell transfer. Cancer Research; 2011: amer assoc cancer research 615 chestnut ST, 17th floor, philadelphia, PA &#8230.

Abdolmohammadi K, Mahmoudi T, Alimohammadi M, Tahmasebi S, Zavvar M, Hashemi SM. Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation. Life Sci. 2023;312:121206.

Article  CAS  PubMed  Google Scholar 

Eshghi F, Tahmasebi S, Alimohammadi M, Soudi S, Khaligh SG, Khosrojerdi A, et al. Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation. Life Sci. 2022;310:120938.

Article  CAS  PubMed  Google Scholar 

Sadeghi S, Tehrani FR, Tahmasebi S, Shafiee A, Hashemi SM. Exosome engineering in cell therapy and drug delivery. Inflammopharmacology. 2023;31(1):145–69.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nielsen T, Kristensen SR, Gregersen H, Teodorescu EM, Christiansen G, Pedersen S. Extracellular vesicle-associated procoagulant phospholipid and tissue factor activity in multiple myeloma. PLoS ONE. 2019;14(1):e0210835.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Purushothaman A, Bandari SK, Liu J, Mobley JA, Brown EE, Sanderson RD. Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions. J Biol Chem. 2016;291(4):1652–63.

Article  CAS  PubMed 

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