Moyzis RK, Buckingham JM, Cram LS, Dani M, Deaven LL, Jones MD, et al. A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci U S A. 1988;85(18):6622–6. https://doi.org/10.1073/pnas.85.18.6622.
Article CAS PubMed PubMed Central Google Scholar
Blackburn EH, Epel ES, Lin J. Human telomere biology: a contributory and interactive factor in aging, disease risks, and protection. Science. 2015;350(6265):1193–8. https://doi.org/10.1126/science.aab3389.
Article CAS PubMed Google Scholar
Demanelis K, Jasmine F, Chen LS, Chernoff M, Tong L, Delgado D, et al. Determinants of telomere length across human tissues. Science. 2020;369(6509):eaaz6876. https://doi.org/10.1126/science.aaz6876.
Ding H, Chen C, Shaffer JR, Liu L, Xu Y, Wang X, et al. Telomere length and risk of stroke in Chinese. Stroke. 2012;43(3):658–63. https://doi.org/10.1161/STROKEAHA.111.637207.
Article CAS PubMed Google Scholar
van der Harst P, van der Steege G, de Boer RA, Voors AA, Hall AS, Mulder MJ, et al. Telomere length of circulating leukocytes is decreased in patients with chronic heart failure. J Am Coll Cardiol. 2007;49(13):1459–64. https://doi.org/10.1016/j.jacc.2007.01.027.
Article CAS PubMed Google Scholar
Brouilette S, Singh RK, Thompson JR, Goodall AH, Samani NJ. White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol. 2003;23(5):842–6. https://doi.org/10.1161/01.ATV.0000067426.96344.32.
Article CAS PubMed Google Scholar
De Meyer T, Rietzschel ER, De Buyzere ML, Van Criekinge W, Bekaert S. Telomere length and cardiovascular aging: the means to the ends? Ageing Res Rev. 2011;10(2):297–303. https://doi.org/10.1016/j.arr.2010.11.001.
Article CAS PubMed Google Scholar
Fyhrquist F, Saijonmaa O, Strandberg T. The roles of senescence and telomere shortening in cardiovascular disease. Nat Rev Cardiol. 2013;10(5):274–83. https://doi.org/10.1038/nrcardio.2013.30.
Article CAS PubMed Google Scholar
Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, et al. Body mass index and leukocyte telomere length dynamics among older adults: results from the ESTHER cohort. Exp Gerontol. 2016;74:1–8. https://doi.org/10.1016/j.exger.2015.11.019.
Article CAS PubMed Google Scholar
Shiels PG, Mcglynn LM, Macintyre A, Johnson PC, Batty GD, Burns H, et al. Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort. PLoS ONE. 2011;6(7): e22521. https://doi.org/10.1371/journal.pone.0022521.
Article CAS PubMed PubMed Central Google Scholar
Needham BL, Adler N, Gregorich S, Rehkopf D, Lin J, Blackburn EH, et al. Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999–2002. Soc Sci Med. 2013;85:1–8. https://doi.org/10.1016/j.socscimed.2013.02.023.
Article PubMed PubMed Central Google Scholar
Weischer M, Bojesen SE, Cawthon RM, Freiberg JJ, Tybjærg-Hansen A, Nordestgaard BG. Short telomere length, myocardial infarction, ischemic heart disease, and early death. Arterioscler Thromb Vasc Biol. 2012;32(3):822–9. https://doi.org/10.1161/ATVBAHA.111.237271.
Article CAS PubMed Google Scholar
Aung N, Wang Q, van Duijvenboden S, Burns R, Stoma S, Raisi-Estabragh Z, et al. Association of longer leukocyte telomere length with cardiac size, function, and heart failure. JAMA Cardiol. 2023;8(9):808–15. https://doi.org/10.1001/jamacardio.2023.2167.
Article PubMed PubMed Central Google Scholar
Vecoli C, Borghini A, Pulignani S, Mercuri A, Turchi S, Picano E, et al. Independent and combined effects of telomere shortening and mtDNA4977 deletion on long-term outcomes of patients with coronary artery disease. Int J Mol Sci. 2019;20(21):5508. https://doi.org/10.3390/ijms20215508.
Zhang A, Fan L, Bao X, Xu Z, Yin Z, Zhuo Y, et al. Leukocyte telomere length shortening implies plaque instability and major adverse cardiovascular events in patients with angiographically intermediate lesions. Front Cardiovasc Med. 2022;8:812363. https://doi.org/10.3389/fcvm.2021.812363.
Mills KT, Stefanescu A, He J. The global epidemiology of hypertension. Nat Rev Nephrol. 2020;16(4):223–37. https://doi.org/10.1038/s41581-019-0244-2.
Article CAS PubMed PubMed Central Google Scholar
Cheng G, Wang L, Dai M, Wei F, Xu D. Shorter leukocyte telomere length coupled with lower expression of telomerase genes in patients with essential hypertension. Int J Med Sci. 2020;17(14):2180–6. https://doi.org/10.7150/ijms.48456.
Article CAS PubMed PubMed Central Google Scholar
Fyhrquist F, Silventoinen K, Saijonmaa O, Kontula K, Devereux RB, de Faire U, et al. Telomere length and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study. J Hum Hypertens. 2011;25(12):711–8. https://doi.org/10.1038/jhh.2011.57.
Article CAS PubMed Google Scholar
Codd V, Denniff M, Swinfield C, Warner SC, Papakonstantinou M, Sheth S, et al. Measurement and initial characterization of leukocyte telomere length in 474,074 participants in UK Biobank. Nat Aging. 2022;2(2):170–9. https://doi.org/10.1038/s43587-021-00166-9.
Article CAS PubMed Google Scholar
Yang Z, Huang X, Jiang H, Zhang Y, Liu H, Qin C, et al. Short telomeres and prognosis of hypertension in a chinese population. Hypertension. 2009;53(4):639–45. https://doi.org/10.1161/HYPERTENSIONAHA.108.123752.
Opstad TB, Kalstad AA, Pettersen AÅ, Arnesen H, Seljeflot I. Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. Exp Gerontol. 2019;119:53–60. https://doi.org/10.1016/j.exger.2019.01.020.
Article CAS PubMed Google Scholar
Deng Y, Li Q, Zhou F, Li G, Liu J, Lv J, et al. Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study. Front Cardiovasc Med. 2022;9:1012615. https://doi.org/10.3389/fcvm.2022.1012615.
Poulter NR, Prabhakaran D, Caulfield M. Hypertension. Lancet. 2015;386(9995):801–12. https://doi.org/10.1016/S0140-6736(14)61468-9.
Schneider CV, Schneider KM, Teumer A, Rudolph KL, Hartmann D, Rader DJ, et al. Association of telomere length with risk of disease and mortality. JAMA Intern Med. 2022;182(3):291–300. https://doi.org/10.1001/jamainternmed.2021.7804.
Article CAS PubMed PubMed Central Google Scholar
Romaine SPR, Denniff M, Codd V, Nath M, Koekemoer A, Anker SD, et al. Telomere length is independently associated with all-cause mortality in chronic heart failure. Heart. 2021;108(2):124–9. https://doi.org/10.1136/heartjnl-2020-318654.
Article CAS PubMed Google Scholar
Fazzini F, Lamina C, Raschenberger J, Schultheiss UT, Kotsis F, Schönherr S, et al. Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease. Kidney Int. 2020;98(2):488–97. https://doi.org/10.1016/j.kint.2020.02.034.
Article CAS PubMed Google Scholar
Fitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, et al. Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2011;66(4):421–9. https://doi.org/10.1093/gerona/glq224.
Article PubMed Central Google Scholar
Arbeev KG, Verhulst S, Steenstrup T, Kark JD, Bagley O, Kooperberg C, et al. Association of leukocyte telomere length with mortality among adult participants in 3 longitudinal studies. JAMA Netw Open. 2020;3(2): e200023. https://doi.org/10.1001/jamanetworkopen.2020.0023.
Article PubMed PubMed Central Google Scholar
Astuti Y, Wardhana A, Watkins J, Wulaningsih W, PILAR Research Network. Cigarette smoking and telomere length: a systematic review of 84 studies and meta-analysis. Environ Res. 2017;158:480–9. https://doi.org/10.1016/j.envres.2017.06.038.
Article CAS PubMed PubMed Central Google Scholar
Huang J, Okuka M, Lu W, Tsibris JC, Mclean MP, Keefe DL, et al. Telomere shortening and DNA damage of embryonic stem cells induced by cigarette smoke. Reprod Toxicol. 2013;35:89–95. https://doi.org/10.1016/j.reprotox.2012.07.003.
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