Wang W, Jiang B, Sun H, Ru X, Sun D, Wang L, et al. Prevalence, incidence, and mortality of stroke in China: results from a nationwide population-based survey of 480 687 adults. Circulation. 2017;135(8):759–71. https://doi.org/10.1161/circulationaha.116.025250.
Zhao Y, Hua X, Ren X, Ouyang M, Chen C, Li Y, et al. Increasing burden of stroke in China: a systematic review and meta-analysis of prevalence, incidence, mortality, and case fatality. Int J Stroke. 2023;18(3):259–67. https://doi.org/10.1177/17474930221135983.
Article CAS PubMed Google Scholar
Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics-2019 update: a report from the American Heart Association. Circulation. 2019;139(10):e56–528. https://doi.org/10.1161/cir.0000000000000659.
Rabinstein AA. Update on treatment of acute ischemic stroke. Continuum (Minneap Minn). 2020;26(2):268–86. https://doi.org/10.1212/con.0000000000000840.
Campbell BCV, Majoie C, Albers GW, Menon BK, Yassi N, Sharma G, et al. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019;18(1):46–55. https://doi.org/10.1016/s1474-4422(18)30314-4.
Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, et al. Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. N Engl J Med. 2019;380(19):1795–803. https://doi.org/10.1056/NEJMoa1813046.
Del Zoppo GJ, Saver JL, Jauch EC, Adams HP Jr. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke. 2009;40(8):2945–8. https://doi.org/10.1161/strokeaha.109.192535.
Article PubMed PubMed Central Google Scholar
Polivka J Jr, Polivka J, Pesta M, Rohan V, Celedova L, Mahajani S, et al. Risks associated with the stroke predisposition at young age: facts and hypotheses in light of individualized predictive and preventive approach. EPMA J. 2019;10(1):81–99. https://doi.org/10.1007/s13167-019-00162-5.
Article PubMed PubMed Central Google Scholar
Torres Crigna A, Link B, Samec M, Giordano FA, Kubatka P, Golubnitschaja O. Endothelin-1 axes in the framework of predictive, preventive and personalised (3p) medicine. EPMA J. 2021;12(3):265–305. https://doi.org/10.1007/s13167-021-00248-z.
Article PubMed PubMed Central Google Scholar
Koklesova L, Mazurakova A, Samec M, Biringer K, Samuel SM, Büsselberg D, et al. Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person. EPMA J. 2021;12(4):477–505. https://doi.org/10.1007/s13167-021-00263-0.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Polivka J Jr, Potuznik P, Pesta M, Stetkarova I, Mazurakova A, et al. The paradigm change from reactive medical services to 3pm in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor and ai-based multi-professional data interpretation. EPMA J. 2024;15(1):1–23. https://doi.org/10.1007/s13167-024-00356-6.
Article PubMed PubMed Central Google Scholar
Xiao Y, Xiao X, Zhang X, Yi D, Li T, Hao Q, et al. Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects. EPMA J. 2024;15(2):207–20. https://doi.org/10.1007/s13167-024-00360-w.
Koklesova L, Mazurakova A, Samec M, Kudela E, Biringer K, Kubatka P, et al. Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine. EPMA J. 2022;13(2):177–93. https://doi.org/10.1007/s13167-022-00281-6.
Article PubMed PubMed Central Google Scholar
Evsevieva M, Sergeeva O, Mazurakova A, Koklesova L, Prokhorenko-Kolomoytseva I, Shchetinin E, et al. Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring. EPMA J. 2022;13(3):351–66. https://doi.org/10.1007/s13167-022-00294-1.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O. Mitochondrion: the subordinated partner who agreed to come short but insists in healthy life. In: Wang W, editor. All around suboptimal health: advanced approaches by predictive, preventive and personalised medicine for healthy populations. Cham: Springer Nature Switzerland; 2024. p. 17–29.
Golubnitschaja O. What is the routine mitochondrial health check-up good for? A holistic approach in the framework of 3p medicine. In: Podbielska H, Kapalla M, editors. Predictive, preventive, and personalised medicine: from bench to bedside. Cham: Springer International Publishing; 2023. p. 19–44.
Kropp M, Golubnitschaja O, Mazurakova A, Koklesova L, Sargheini N, Vo TKS, et al. Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications-risks and mitigation. EPMA J. 2023;14(1):21–42. https://doi.org/10.1007/s13167-023-00314-8.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Flammer J. Individualised patient profile: clinical utility of Flammer syndrome phenotype and general lessons for predictive, preventive and personalised medicine. EPMA J. 2018;9(1):15–20. https://doi.org/10.1007/s13167-018-0127-9.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Liskova A, Koklesova L, Samec M, Biringer K, Büsselberg D, et al. Caution, “normal” bmi: health risks associated with potentially masked individual underweight-epma position paper 2021. EPMA J. 2021;12(3):243–64. https://doi.org/10.1007/s13167-021-00251-4.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Kapinova A, Sargheini N, Bojkova B, Kapalla M, Heinrich L, et al. Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care-clinically relevant 3pm innovation. EPMA J. 2024;15(2):163–205. https://doi.org/10.1007/s13167-024-00358-4.
Article PubMed PubMed Central Google Scholar
Golubnitschaja O, Potuznik P, Polivka J Jr, Pesta M, Kaverina O, Pieper CC, et al. Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach. EPMA J. 2022;13(4):535–45. https://doi.org/10.1007/s13167-022-00307-z.
Article PubMed PubMed Central Google Scholar
Kropp M, De Clerck E, Vo TKS, Thumann G, Costigliola V, Golubnitschaja O. Short communication: unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities - preliminary data for pppm validation. EPMA J. 2023;14(1):43–51. https://doi.org/10.1007/s13167-023-00318-4.
Article PubMed PubMed Central Google Scholar
Zou D, Luo M, Han Z, Zhan L, Zhu W, Kang S, et al. Activation of alpha-7 nicotinic acetylcholine receptor reduces brain edema in mice with ischemic stroke and bone fracture. Mol Neurobiol. 2017;54(10):8278–86. https://doi.org/10.1007/s12035-016-0310-8.
Article CAS PubMed Google Scholar
Astrup J, Siesjö BK, Symon L. Thresholds in cerebral ischemia - the ischemic penumbra. Stroke. 1981;12(6):723–5. https://doi.org/10.1161/01.str.12.6.723.
Article CAS PubMed Google Scholar
Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999;22(9):391–7. https://doi.org/10.1016/s0166-2236(99)01401-0.
Article CAS PubMed Google Scholar
Ramos-Cabrer P, Campos F, Sobrino T, Castillo J. Targeting the ischemic penumbra. Stroke. 2011;42(1 Suppl):S7-11. https://doi.org/10.1161/strokeaha.110.596684.
Chamorro A, Hallenbeck J. The harms and benefits of inflammatory and immune responses in vascular disease. Stroke. 2006;37(2):291–3. https://doi.org/10.1161/01.STR.0000200561.69611.f8.
Article PubMed PubMed Central Google Scholar
Arbaizar-Rovirosa M, Gallizioli M, Lozano JJ, Sidorova J, Pedragosa J, Figuerola S, et al. Transcriptomics and translatomics identify a robust inflammatory gene signature in brain endothelial cells after ischemic stroke. J Neuroinflammation. 2023;20(1):207. https://doi.org/10.1186/s12974-023-02888-6.
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