Verkhratsky A, Parpura V, Rodriguez-Arellano JJ, Zorec R. Astroglia in Alzheimer’s Disease. Adv Exp Med Biol. 2019;1175:273–324.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Verkhratsky A, Butt A, Li B, Illes P, Zorec R, Semyanov A, et al. Astrocytes In Human Central Nervous System Diseases: A Frontier For New Therapies. Signal Transduct Target Ther. 2023;8:1–37.

Google Scholar 

Sonninen T-M, Hämäläinen RH, Koskuvi M, Oksanen M, Shakirzyanova A, Wojciechowski S, et al. Metabolic Alterations In Parkinson’s Disease Astrocytes. Sci Rep. 2020;10:14474.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tripathi P, Rodriguez-Muela N, Klim JR, de Boer AS, Agrawal S, Sandoe J, et al. Reactive Astrocytes Promote Als-Like Degeneration And Intracellular Protein Aggregation In Human Motor Neurons By Disrupting Autophagy Through Tgf-Β1. Stem Cell Rep. 2017;9:667–80.

Article  CAS  Google Scholar 

Fontana IC, Scarpa M, Malarte M-L, Rocha FM, Ausellé-Bosch S, Bluma M, et al. Astrocyte Signature in Alzheimer’s Disease Continuum through a Multi-PET Tracer Imaging Perspective. Cells. 2023;12:1469.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matyash V, Kettenmann H. Heterogeneity In Astrocyte Morphology And Physiology. Brain Res Rev. 2010;63:2–10.

Article  CAS  PubMed  Google Scholar 

Molofsky AV, Deneen B. Astrocyte development: A Guide for the Perplexed. Glia. 2015;63:1320–9.

Article  PubMed  Google Scholar 

Namihira M, Kohyama J, Semi K, Sanosaka T, Deneen B, Taga T, et al. Committed Neuronal Precursors Confer Astrocytic Potential On Residual Neural Precursor Cells. Dev Cell. 2009;16:245–55.

Article  CAS  PubMed  Google Scholar 

Barnabé-Heider F, Wasylnka JA, Fernandes KJL, Porsche C, Sendtner M, Kaplan DR, et al. Evidence That Embryonic Neurons Regulate The Onset Of Cortical Gliogenesis Via Cardiotrophin-1. Neuron. 2005;48:253–65.

Article  PubMed  Google Scholar 

Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, Christopherson KS, et al. A Transcriptome Database For Astrocytes, Neurons, And Oligodendrocytes: A New Resource For Understanding Brain Development And Function. J Neurosci Off J Soc Neurosci. 2008;28:264–78.

Article  CAS  Google Scholar 

Escartin C, Galea E, Lakatos A, O’Callaghan JP, Petzold GC, Serrano-Pozo A, et al. Reactive Astrocyte Nomenclature, Definitions, And Future Directions. Nat Neurosci. 2021;24:312–25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nishiyama A, Suzuki R, Zhu X. Ng2 Cells (Polydendrocytes) In Brain Physiology And Repair. Front Neurosci. 2014;8:133.

Article  PubMed  PubMed Central  Google Scholar 

Un nuevo proceder para la impregnación de la neuroglia [A new procedure for the impregnation of neuroglia]. Boletín de la Sociedad Española de Biologia. 2:104–8.

Schober AL, Wicki-Stordeur LE, Murai KK, Swayne LA. Foundations And Implications Of Astrocyte Heterogeneity During Brain Development And Disease. Trends Neurosci. 2022;45:692–703.

Article  CAS  PubMed  Google Scholar 

Fan Y-Y, Huo J. A1/A2 Astrocytes In Central Nervous System Injuries And Diseases: Angels Or Devils? Neurochem Int. 2021;148: 105080.

Article  CAS  PubMed  Google Scholar 

Rodríguez-Giraldo M, González-Reyes RE, Ramírez-Guerrero S, Bonilla-Trilleras CE, Guardo-Maya S, Nava-Mesa MO. Astrocytes as a Therapeutic Target in Alzheimer’s Disease-Comprehensive Review and Recent Developments. Int J Mol Sci. 2022;23:13630.

Article  PubMed  PubMed Central  Google Scholar 

Šerý O, Goswami N, Balcar VJ. Chapter 4 - CD36 gene polymorphisms and Alzheimer’s disease. In: Martin CR, Preedy VR, editors. Genet Neurol Behav Diet Dement. Academic Press; 2020. p. 57–70. Available from: https://www.sciencedirect.com/science/article/pii/B9780128158685000049.  Cited 2024 Jun 20.

Krencik R, Zhang S-C. Directed Differentiation of Functional Astroglial Subtypes from Human Pluripotent Stem Cells. Nat Protoc. 2011;6:1710–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tyzack G, Lakatos A, Patani R. Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological Disorders. Curr Stem Cell Rep. 2016;2:236–47.

Article  PubMed  PubMed Central  Google Scholar 

Tcw J, Wang M, Pimenova AA, Bowles KR, Hartley BJ, Lacin E, et al. An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells. Stem Cell Rep. 2017;9:600–14.

Article  CAS  Google Scholar 

Foo LC, Allen NJ, Bushong EA, Ventura PB, Chung W-S, Zhou L, et al. Development of a Novel Method for the Purification and Culture of Rodent Astrocytes. Neuron. 2011;71:799–811.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magistri M, Khoury N, Mazza EMC, Velmeshev D, Lee JK, Bicciato S, et al. A Comparative Transcriptomic Analysis Of Astrocytes Differentiation From Human Neural Progenitor Cells. Eur J Neurosci. 2016;44:2858–70.

Article  PubMed  PubMed Central  Google Scholar 

Perriot S, Mathias A, Perriard G, Canales M, Jonkmans N, Merienne N, et al. Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines. Stem Cell Rep. 2018;11:1199–210.

Article  CAS  Google Scholar 

Perriot S, Canales M, Mathias A, Du Pasquier R. Differentiation of functional astrocytes from human-induced pluripotent stem cells in chemically defined media. STAR Protoc. 2021;2: 100902.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Y, Sloan SA, Clarke LE, Caneda C, Plaza CA, Blumenthal PD, et al. Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse. Neuron. 2016;89:37–53.

Article  CAS  PubMed  Google Scholar 

Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, et al. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science. 1997;278:477–83.

Article  CAS  PubMed  Google Scholar 

Chandrasekaran A, Avci HX, Leist M, Kobolák J, Dinnyés A. Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research. Front Cell Neurosci. 2016;10:215.

Article  PubMed  PubMed Central  Google Scholar 

Mulica P, Venegas C, Landoulsi Z, Badanjak K, Delcambre S, Tziortziou M, et al. Comparison Of Two Protocols For The Generation Of Ipsc-Derived Human Astrocytes. Biol Proced Online. 2023;25:26.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Szeky B, Feher A, Zana M, Kucera R, Lochman J, Dinnyes A. Differentiation of Astrocytes from Human iPSC-derived NPCs. protocols.io. 2024. https://doi.org/10.17504/protocols.io.x54v9pb4mg3e/v1

Chambers SM, Fasano CA, Papapetrou EP, Tomishima M, Sadelain M, Studer L. Highly Efficient Neural Conversion Of Human Es And Ips Cells By Dual Inhibition Of Smad Signaling. Nat Biotechnol. 2009;27:275–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, et al. Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation. Stem Cells Int. 2016;2016:4937689.

Article  PubMed  Google Scholar 

Chandrasekaran A, Avci HX, Ochalek A, Rösingh LN, Molnár K, László L, et al. Comparison Of 2d And 3d Neural Induction Methods For The Generation Of Neural Progenitor Cells From Human Induced Pluripotent Stem Cells. Stem Cell Res. 2017;25:139–51.

Article  CAS  PubMed  Google Scholar 

Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, et