Abe O, Okubo T, Hayashi N, Saito N, Iriguchi N, Shirouzu I, Kojima Y, Masumoto T, Ohtomo K, Sasaki Y (2000) Temporal changes of the apparent diffusion coefficients of water and metabolites in rats with hemispheric infarction: experimental study of transhemispheric diaschisis in the contralateral hemisphere at 7 tesla. J Cereb Blood Flow Metab 20:726–735
Albeanu DF, Provost AC, Agarwal P, Soucy ER, Zak JD, Murthy VN (2018) Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map. Nat Commun 9:5073
Article PubMed Central Google Scholar
Beal CC (2010) Gender and stroke symptoms: a review of the current literature. J Neurosci Nurs 42:80–87
Becker K, Kindrick D, Relton J, Harlan J, Winn R (2001) Antibody to the alpha4 integrin decreases infarct size in transient focal cerebral ischemia in rats. Stroke 32:206–211
Bramlett HM, Dietrich WD (2004) Pathophysiology of cerebral ischemia and brain trauma: similarities and differences. J Cereb Blood Flow Metab 24:133–150
Chang LH, Lin HC, Huang SS, Chen IC, Chu KW, Chih CL, Liang YW, Lee YC, Chen YY, Lee YH, Lee IH (2018) Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation. Sci Rep 8:118
Article PubMed Central Google Scholar
Chen Y, Tian H, Yao E, Tian Y, Zhang H, Xu L, Yu Z, Fang Y, Wang W, Du P, Xie M (2017) Soluble epoxide hydrolase inhibition promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in mice. Sci Rep 7:7758
Article PubMed Central Google Scholar
Chhor V, Le Charpentier T, Lebon S, Ore MV, Celador IL, Josserand J, Degos V, Jacotot E, Hagberg H, Savman K, Mallard C, Gressens P, Fleiss B (2013) Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro. Brain Behav Immun 32:70–85
Article PubMed Central CAS Google Scholar
Dintica CS, Marseglia A, Rizzuto D, Wang R, Seubert J, Arfanakis K, Bennett DA, Xu W (2019) Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain. Neurology 92:e700–e709
Article PubMed Central Google Scholar
Doty RL (2017) Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate? Lancet Neurol 16:478–488
Fonteyn S, Huart C, Deggouj N, Collet S, Eloy P, Rombaux P (2014) Non-sinonasal-related olfactory dysfunction: a cohort of 496 patients. Eur Ann Otorhinolaryngol Head Neck Dis 131:87–91
Han L, Cai W, Mao L, Liu J, Li P, Leak RK, Xu Y, Hu X, Chen J (2015) Rosiglitazone promotes White Matter Integrity and Long-Term Functional Recovery after focal cerebral ischemia. Stroke 46:2628–2636
Article PubMed Central CAS Google Scholar
Heckmann JG, Stossel C, Lang CJ, Neundorfer B, Tomandl B, Hummel T (2005) Taste disorders in acute stroke: a prospective observational study on taste disorders in 102 stroke patients. Stroke 36:1690–1694
Hochmeister S, Engel O, Adzemovic MZ, Pekar T, Kendlbacher P, Zeitelhofer M, Haindl M, Meisel A, Fazekas F, Seifert-Held T (2016) Lipocalin-2 as an infection-related biomarker to Predict Clinical Outcome in ischemic stroke. PLoS ONE 11:e0154797
Article PubMed Central Google Scholar
Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, Gao Y, Chen J (2012) Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 43:3063–3070
Hummel T et al (2017) Position paper on olfactory dysfunction. Rhinol Suppl 54:1–30
Hung YW, Hung SW, Wu YC, Wong LK, Lai MT, Shih YH, Lee TS, Lin YY (2015) Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain Behav Immun 43:118–129
Hung TH, Shyue SK, Wu CH, Chen CC, Lin CC, Chang CF, Chen SF (2017) Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury. Oncotarget 8:103236–103260
Article PubMed Central Google Scholar
Iliff JJ, Alkayed NJ (2009) Soluble Epoxide Hydrolase Inhibition: Targeting multiple mechanisms of ischemic brain Injury with a single Agent. Future Neurol 4:179–199
Article PubMed Central CAS Google Scholar
Imig JD (2012) Epoxides and soluble epoxide hydrolase in cardiovascular physiology. Physiol Rev 92:101–130
Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD (2013) Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS ONE 8:e80922
Article PubMed Central Google Scholar
Jayaraj RL, Azimullah S, Beiram R, Jalal FY, Rosenberg GA (2019) Neuroinflammation: friend and foe for ischemic stroke. J Neuroinflammation 16:142
Article PubMed Central Google Scholar
Jin R, Yang G, Li G (2010) Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol 87:779–789
Article PubMed Central CAS Google Scholar
Kagoya R, Toma-Hirano M, Yamagishi J, Matsumoto N, Kondo K, Ito K (2022) Immunological status of the olfactory bulb in a murine model of toll-like receptor 3-mediated upper respiratory tract inflammation. J Neuroinflammation 19:13
Article PubMed Central CAS Google Scholar
Kim E, Cho S (2016) Microglia and Monocyte-Derived macrophages in Stroke. Neurotherapeutics 13:702–718
Article PubMed Central CAS Google Scholar
Kim J, Ahn M, Choi Y, Ekanayake P, Park CM, Moon C, Jung K, Tanaka A, Matsuda H, Shin T (2019) Gene expression profile of olfactory transduction signaling in an animal model of human multiple sclerosis. Exp Neurobiol 28:74–84
Article PubMed Central Google Scholar
Koerner IP, Zhang W, Cheng J, Parker S, Hurn PD, Alkayed NJ (2008) Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia. Front Biosci 13:2833–2841
Article PubMed Central CAS Google Scholar
Kohl Z, Schlachetzki JC, Feldewerth J, Hornauer P, Munch M, Adame A, Riemenschneider MJ, Winkler J, Masliah E (2017) Distinct pattern of microgliosis in the olfactory bulb of neurodegenerative proteinopathies. Neural Plast 2017:3851262
Kuo YM, Lee YH (2022) Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system. Chin J Physiol 65:1–11
Kuriakose D, Xiao Z (2020) Pathophysiology and treatment of stroke: present status and future perspectives. Int J Mol Sci 21:7609
Kuruppath P, Xue L, Pouille F, Jones ST, Schoppa NE (2023) Hyperexcitability in the olfactory bulb and impaired fine odor discrimination in the Fmr1 KO mouse model of Fragile X Syndrome. J Neurosci 43:8243–8258
Article PubMed Central CAS Google Scholar
Lai AY, Todd KG (2006) Microglia in cerebral ischemia: molecular actions and interactions. Can J Physiol Pharmacol 84:49–59
Lalancette-Hebert M, Phaneuf D, Soucy G, Weng YC, Kriz J (2009) Live imaging of toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation. Brain 132:940–954
Lalancette-Hebert M, Moquin A, Choi AO, Kriz J, Maysinger D (2010) Lipopolysaccharide-QD micelles induce marked induction of TLR2 and lipid droplet accumulation in olfactory bulb microglia. Mol Pharm 7:1183–1194
Lazarini F, Gabellec MM, Torquet N, Lledo PM (2012) Early activation of microglia triggers long-lasting impairment of adult neurogenesis in the olfactory bulb. J Neurosci 32:3652–3664
Article PubMed Central CAS Google Scholar
Lipton P (1999) Ischemic cell death in brain neurons. Physiol Rev 79:1431–1568
Liu Y, Wan Y, Fang Y, Yao E, Xu S, Ning Q, Zhang G, Wang W, Huang X, Xie M (2016) Epoxyeicosanoid Signaling provides Multi-target Protective effects on neurovascular unit in rats after focal ischemia. J Mol Neurosci 58:254–265
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