∗Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

†Pittsburgh Trauma & Transfusion Medicine Research Center, University of Pittsburgh, Pittsburgh, PA

‡Department of Surgery, Brigham and Women's Hospital/Harvard Medical School, Boston, MA

§Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA

Received 30 Aug 2022; first review completed 20 Sep 2022; accepted in final form 28 Oct 2022

Address reprint requests to: Anupamaa Seshadri, MD, Beth Israel Deaconess Medical Center, 110 Francis St, Lowry 2G, Boston, MA 02215. E-mail: [email protected]

MDN is on Scientific Advisory Board of Haima Therapeutics and receives research funding from DoD, NIH, Janssen, Haemonetics, and Instrumentation Laboratory and honoraria from Meredian, Haemonetics, and CSL Behring. The other authors report no conflicts of interest.