∗Department of Cardiology, Affiliated Hospital of Zunyi Medical University, Guizhou, China

†Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China

Received 23 Mar 2023; first review completed 17 Apr 2023; accepted in final form 27 Jul 2023

Address reprint requests to Bei Shi, MD, Department of Cardiology, Affiliated Hospital of Zunyi Medical University, Guizhou, China. E- mail: [email protected]; Co-correspondence: Junbo Ge, MD, Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China. E-mail: [email protected]; Ranzun Zhao PhD, Department of Cardiology, Affiliated Hospital of Zunyi Medical University, Guizhou, China. E-mail: [email protected]

Yu Zhang, Yan Wang, and Jiao Li contributed equally to this work.

Funding: This study was supported by a scientific research project by the National Natural Science Foundation of China (grant nos 82200316, 82160057, and 81860061) and by the Guizhou Province Science and Technology Plan Project (grant nos [2021]353 and [2022]628). This study was also supported by the Science and Technology Fund of the Guizhou Provincial Health and Health Commission (gzwjkj2020-1-064).

Data availability statement: The datasets used and analyzed during the current study are available from the corresponding author upon reasonable request.

Author Contributions: Bei Shi, Junbo Ge, and Ranzun Zhao designed the study. Yan Wang, Yu Zhang, and Jiao Li completed the experimental process. Chaofu Li and Weiwei Liu participated in part of the experiments. XianPing Long and Zhenglong Wang analyzed the data and performed statistical analysis. Bei Shi, Yu Zhang, and Yan Wang wrote and revised the manuscript with contributions from all other authors. All authors reviewed and approved the final manuscript.

Declaration of interests: The authors have no conflicts of interest to declare.

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