Postmortem examination holds a pivotal role in our society. The implications of this procedure are vast, ranging from medicolegal consequences to characterisation of heritable genetic syndromes and closure for those proximal to the deceased. Despite its widespread intrinsic value, a surprising 1%–5% of postmortem examinations will lack revealing gross, histologic, or laboratory findings that inform the cause of death.1 2 The so-called ‘negative autopsy’ is a challenge for the medical system and relatives of the deceased alike.

A specific list of differential diagnoses is considered in the setting of a negative autopsy. Among potential causes, cardiac aetiologies are common due to the complex nature of the organ and the electrical systems within. Specifically, arrhythmogenic …