Kingsbury, S. R. et al. Pain reduction with oral methotrexate in knee osteoarthritis: a randomized, placebo-controlled clinical trial. Ann. Intern. Med. 177, 1145–1156 (2024).

Article  PubMed  Google Scholar 

Bai, Z. et al. Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Sci. Transl. Med. 16, eadk3506 (2024).

Article  CAS  PubMed  Google Scholar 

Chen, C. et al. Neural circuit basis of placebo pain relief. Nature. 632, 1092–1100 (2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kolasinski, S. L. et al. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis Rheumatol. 72, 220–233 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Wang, Y. et al. Methotrexate to treat hand osteoarthritis with synovitis (METHODS): an Australian, multisite, parallel-group, double-blind, randomised, placebo-controlled trial. Lancet 402, 1764–1772 (2023).

Article  CAS  PubMed  Google Scholar 

Colloca, L. & Barsky, A. J. Placebo and nocebo effects. N. Engl. J. Med. 382, 554–561 (2020).

Article  CAS  PubMed  Google Scholar