National Human Genome Research Institute. Precision Medicine. https://www.genome.gov/genetics-glossary/Precision-Medicine (2024).
Costa, A. et al. From “Inclusion in What” to “Equity in What”: (Re)thinking the question of in/equity in precision medicine and health. Am. J. Bioeth. 24, 89–91 (2024).
CDC. Health Equity. https://www.cdc.gov/healthequity/whatis/index.html (2024).
Khoury, M. J. et al. Health equity in the implementation of genomics and precision medicine: a public health imperative. Genet. Med. 24, 1630–1639 (2022).
Article CAS PubMed PubMed Central Google Scholar
Allen, C. G. et al. Extending an antiracism lens to the implementation of precision public health interventions. Am. J. Public. Health 113, 1210–1218 (2023).
Article PubMed PubMed Central Google Scholar
Matthew, D. B. Two threats to precision medicine equity. Ethn. Dis. 29, 629–640 (2019).
Article PubMed PubMed Central Google Scholar
Odutola, J. & Ward, M. M. Ethnic and socioeconomic disparities in health among patients with rheumatic disease. Curr. Opin. Rheumatol. 17, 147–152 (2005).
Khoury, M. J., Iademarco, M. F. & Riley, W. T. Precision public health for the era of precision medicine. Am. J. Prev. Med. 50, 398–401 (2016).
Cohn, E. G., Henderson, G. E. & Appelbaum, P. S. Distributive justice, diversity, and inclusion in precision medicine: what will success look like? Genet. Med. 19, 157–159 (2017).
Sabatello, M. Precision medicine, health disparities, and ethics: the case for disability inclusion. Genet. Med. 20, 397–399 (2018).
Cho, M. K. et al. Words matter: the language of difference in human genetics. Genet. Med. 25, 100343 (2023).
Article CAS PubMed Google Scholar
Lopez, K. N. & Fuentes-Afflick, E. Engaging pediatric subspecialists in pursuit of health equity-breaking out of the silo. JAMA Pediatr. 176, 841–842 (2022).
Richardson, A., Darst, B., Wojcik, G., Wagle, N. & Haricharan, S. Research silos in cancer disparities: obstacles to improving clinical outcomes for underserved patient populations. Clin. Cancer Res. 29, 1194–1199 (2023).
Article PubMed PubMed Central Google Scholar
Pryor, K. P., Barbhaiya, M., Costenbader, K. H. & Feldman, C. H. Disparities in lupus and lupus nephritis care and outcomes among US Medicaid beneficiaries. Rheum. Dis. Clin. North. Am. 47, 41–53 (2021).
Gillis, J. Z. et al. Medicaid and access to care among persons with systemic lupus erythematosus. Arthritis Rheum. 57, 601–607 (2007).
Article PubMed PubMed Central Google Scholar
Widdifield, J. et al. Access to rheumatologists among patients with newly diagnosed rheumatoid arthritis in a Canadian universal public healthcare system. BMJ Open. 4, e003888 (2014).
Article PubMed PubMed Central Google Scholar
Barnabe, C. Disparities in rheumatoid arthritis care and health service solutions to Equity. Rheum. Dis. Clin. North. Am. 46, 685–692 (2020).
Green, S., Prainsack, B. & Sabatello, M. The roots of (in)equity in precision medicine: gaps in the discourse. Per. Med. 21, 5–9 (2024).
Article CAS PubMed Google Scholar
Green, S., Prainsack, B. & Sabatello, M. Precision medicine and the problem of structural injustice. Med. Health Care Philos. 26, 433–450 (2023).
Article PubMed PubMed Central Google Scholar
Tabery, J. Tyranny of the Gene. Personalized Medicine and its Tread to Public Health. (Penguin Random House, 2023).
Ory, M. G., Adepoju, O. E., Ramos, K. S., Silva, P. S. & Vollmer Dahlke, D. Health equity innovation in precision medicine: current challenges and future directions. Front. Public. Health 11, 1119736 (2023).
Article PubMed PubMed Central Google Scholar
Ramos, P. S. & Lim, S. S. Clarity for the language of race, ethnicity and genetic ancestry in rheumatology. Nat. Rev. Rheumatol. 384, 474–454 (2024).
Borrell, L. N. et al. Race and genetic ancestry in medicine — a time for reckoning with racism. N. Engl. J. Med. 384, 474–480 (2021).
Article PubMed PubMed Central Google Scholar
Gordon, N. P., Lin, T. Y., Rau, J. & Lo, J. C. Aggregation of Asian-American subgroups masks meaningful differences in health and health risks among Asian ethnicities: an electronic health record based cohort study. BMC Public. Health 19, 1551 (2019).
Article PubMed PubMed Central Google Scholar
Hudson, D. L. et al. Are benefits conferred with greater socioeconomic position undermined by racial discrimination among African American men? J. Mens Health 9, 127–136 (2012).
Article PubMed PubMed Central Google Scholar
Colen, C. G., Ramey, D. M., Cooksey, E. C. & Williams, D. R. Racial disparities in health among nonpoor African Americans and Hispanics: the role of acute and chronic discrimination. Soc. Sci. Med. 199, 167–180 (2018).
Williams, D. R., Mohammed, S. A., Leavell, J. & Collins, C. Race, socioeconomic status, and health: complexities, ongoing challenges, and research opportunities. Ann. NY Acad. Sci. 1186, 69–101 (2010).
National Academies of Sciences, Engineering & Medicine. Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field. (The National Academies Press, 2023).
Roth, W. D. The multiple dimensions of race. Ethn. Racial Stud. 39, 1310–1338 (2016).
Chae, D. H., Nuru-Jeter, A. M., Lincoln, K. D. & Francis, D. D. Conceptualizing racial disparities in health: advancement of a socio-psychobiological approach. Du Bois Rev. 8, 63–77 (2011).
Feero, W. G. et al. Guidance on use of race, ethnicity, and geographic origin as proxies for genetic ancestry groups in biomedical publications. JAMA 331, 1276–1278 (2024).
Engel, G. L. The need for a new medical model: a challenge for biomedicine. Science 196, 129–136 (1977).
Article CAS PubMed Google Scholar
Clark, R., Anderson, N. B., Clark, V. R. & Williams, D. R. Racism as a stressor for African Americans. A biopsychosocial model. Am. Psychol. 54, 805–816 (1999).
Article CAS PubMed Google Scholar
Gee, G. C. & Payne-Sturges, D. C. Environmental health disparities: a framework integrating psychosocial and environmental concepts. Env. Health Perspect. 112, 1645–1653 (2004).
Harrell, C. J. et al. Multiple pathways linking racism to health outcomes. Du Bois Rev. 8, 143–157 (2011).
Article PubMed PubMed Central Google Scholar
Martenies, S. E., Milando, C. W., Williams, G. O. & Batterman, S. A. Disease and health inequalities attributable to air pollutant exposure in Detroit, Michigan. Int. J. Environ. Res. Public Health 14, 1243 (2017).
Chambliss, S. E. et al. Local- and regional-scale racial and ethnic disparities in air pollution determined by long-term mobile monitoring. Proc. Natl Acad. Sci. USA 118, e2109249118 (2021).
Article CAS PubMed PubMed Central Google Scholar
Jbaily, A. et al. Air pollution exposure disparities across US population and income groups. Nature 601, 228–233 (2022).
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