World Health Organization. Ageing and health, https://www.who.int/news-room/fact-sheets/detail/ageing-and-health, Accessed 8 Sept 2024.
May RL. Rudolph the red-nosed reindeer. Chicago, Illinois, United States of America: Montgomery Ward. Applewood Books, U.S.;1939.
Kahan BC, Hindley J, Edwards M, Cro S, Morris TP. The estimands framework: a primer on the ICH E9(R1) addendum. BMJ. 2024;384: e076316.
Article PubMed PubMed Central Google Scholar
Kahan BC, Morris TP, Cro S. We must let the research question drive study methods. BMJ. 2024;384: q173.
Cro S, Kahan BC, Rehal S, Chis Ster A, Carpenter JR, White IR, et al. Evaluating how clear the questions being investigated in randomised trials are: systematic review of estimands. BMJ. 2022;378: e070146.
Article PubMed PubMed Central Google Scholar
Cro S. Time to improve the clarity of clinical trial reports by including estimands. BMJ. 2022;378: o2108.
Quartagno M, Morris TP, Gilbert DC, Langley RE, Nankivell MG, Parmar MK, et al. A comparison of different population-level summary measures for randomised trials with time-to-event outcomes, with a focus on non-inferiority trials. Clin Trials. 2023;20(6):594–602.
Article PubMed PubMed Central Google Scholar
Rombach I, Knight R, Peckham N, Stokes JR, Cook JA. Current practice in analysing and reporting binary outcome data—a review of randomised controlled trial reports. BMC Med. 2020;18(1):147.
Article PubMed PubMed Central Google Scholar
Kahan BC, Morris TP, White IR, Tweed CD, Cro S, Dahly D, et al. Treatment estimands in clinical trials of patients hospitalised for COVID-19: ensuring trials ask the right questions. BMC Med. 2020;18(1):286.
Article CAS PubMed PubMed Central Google Scholar
International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use. Addendum on Estimands and Sensitivity Analysis in Clinical Trials to the Guideline on Statistical Principles for Clinical Trials 20 November 2019. https://www.ema.europa.eu/en/documents/scientific-guideline/iche9-r1-addendum-estimands-and-sensitivity-analysis-clinical-trials-guideline-statistical-principles-clinical-trials-step-5_en.pdf.
Cro S, Morris TP, Kahan BC, Cornelius VR, Carpenter JR. A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic. BMC Med Res Methodol. 2020;20(1):208.
Article CAS PubMed PubMed Central Google Scholar
Van Lancker K, Tarima S, Bartlett J, Bauer M, Bharani-Dharan B, Bretz F, et al. Estimands and their estimators for clinical trials impacted by the COVID-19 pandemic: a report from the NISS Ingram Olkin Forum Series on unplanned clinical trial disruptions. Statistics in Biopharmaceutical Research. 2023;15(1):94–111.
Olarte Parra C, Daniel RM, Bartlett JW. Hypothetical estimands in clinical trials: a unification of causal inference and missing data methods. Stat Biopharm Res. 2023;15(2):421–32.
Kahan BC, Morris TP, White IR, Carpenter J, Cro S. Estimands in published protocols of randomised trials: urgent improvement needed. Trials. 2021;22(1):686.
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