iRhom2 deficiency reduces sepsis-induced mortality associated with the attenuation of lung macrophages in mice

Adrain C, Zettl M, Christova Y, Taylor N, Freeman M (2012) Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. Science (new York, NY) 335(6065):225–228. https://doi.org/10.1126/science.1214400

Article  CAS  Google Scholar 

Alvira CM (2014) Nuclear factor-kappa-B signaling in lung development and disease: one pathway, numerous functions. Birth Defects Res A Clin Mol Teratol 100(3):202–216. https://doi.org/10.1002/bdra.23233

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beck-Schimmer B, Schwendener R, Pasch T, Reyes L, Booy C, Schimmer RC (2005) Alveolar macrophages regulate neutrophil recruitment in endotoxin-induced lung injury. Respir Res 6(1):61. https://doi.org/10.1186/1465-9921-6-61

Article  CAS  PubMed  PubMed Central  Google Scholar 

Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385(6618):729–733. https://doi.org/10.1038/385729a0

Article  CAS  PubMed  Google Scholar 

Calligaris M, Cuffaro D, Bonelli S, Spanò DP, Rossello A, Nuti E, Scilabra SD (2021) Strategies to target ADAM17 in disease: from its discovery to the irhom revolution. Molecules. https://doi.org/10.3390/molecules26040944

Article  PubMed  PubMed Central  Google Scholar 

Cauvi DM, Song D, Vazquez DE, Hawisher D, Bermudez JA, Williams MR, Bickler S, Coimbra R, De Maio A (2012) Period of irreversible therapeutic intervention during sepsis correlates with phase of innate immune dysfunction. J Biol Chem 287(24):19804–19815. https://doi.org/10.1074/jbc.M112.359562

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chenxu G, Minxuan X, Yuting Q, Tingting G, Jinxiao L, Mingxing W, Sujun W, Yongjie M, Deshuai L, Qiang L, Linfeng H, Jun T (2018) iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress. Redox Biol 19:147–157. https://doi.org/10.1016/j.redox.2018.08.009

Article  CAS  PubMed  PubMed Central  Google Scholar 

Costa EL, Schettino IA, Schettino GP (2006) The lung in sepsis: guilty or innocent? Endocr Metab Immune Disord Drug Targets 6(2):213–216. https://doi.org/10.2174/187153006777442413

Article  CAS  PubMed  Google Scholar 

Dushianthan A, Grocott MP, Postle AD, Cusack R (2011) Acute respiratory distress syndrome and acute lung injury. Postgrad Med J 87(1031):612–622. https://doi.org/10.1136/pgmj.2011.118398

Article  CAS  PubMed  Google Scholar 

Fan EKY, Fan J (2018) Regulation of alveolar macrophage death in acute lung inflammation. Respir Res 19(1):50. https://doi.org/10.1186/s12931-018-0756-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Georgescu AM, Banescu C, Azamfirei R, Hutanu A, Moldovan V, Badea I, Voidazan S, Dobreanu M, Chirtes IR, Azamfirei L (2020) Evaluation of TNF-α genetic polymorphisms as predictors for sepsis susceptibility and progression. BMC Infect Dis 20(1):221. https://doi.org/10.1186/s12879-020-4910-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gharamti AA, Samara O, Monzon A, Montalbano G, Scherger S, DeSanto K, Chastain DB, Sillau S, Montoya JG, Franco-Paredes C, Henao-Martínez AF, Shapiro L (2022) Proinflammatory cytokines levels in sepsis and healthy volunteers, and tumor necrosis factor-alpha associated sepsis mortality: a systematic review and meta-analysis. Cytokine 158:156006. https://doi.org/10.1016/j.cyto.2022.156006

Article  CAS  PubMed  Google Scholar 

Gong H, Chen Y, Chen M, Li J, Zhang H, Yan S, Lv C (2022) Advanced development and mechanism of sepsis-related acute respiratory distress syndrome. Front Med (lausanne) 9:1043859. https://doi.org/10.3389/fmed.2022.1043859

Article  PubMed  Google Scholar 

Hirano Y, Aziz M, Yang WL, Wang Z, Zhou M, Ochani M, Khader A, Wang P (2015) Neutralization of osteopontin attenuates neutrophil migration in sepsis-induced acute lung injury. Crit Care 19(1):53. https://doi.org/10.1186/s13054-015-0782-3

Article  PubMed  PubMed Central  Google Scholar 

Hubbard WJ, Choudhry M, Schwacha MG, Kerby JD, Rue LW 3rd, Bland KI, Chaudry IH (2005) Cecal ligation and puncture. Shock 24(Suppl 1):52–57. https://doi.org/10.1097/01.shk.0000191414.94461.7e

Article  PubMed  Google Scholar 

Karin M, Lin A (2002) NF-kappaB at the crossroads of life and death. Nat Immunol 3(3):221–227. https://doi.org/10.1038/ni0302-221

Article  CAS  PubMed  Google Scholar 

Kasten KR, Tschöp J, Adediran SG, Hildeman DA, Caldwell CC (2010) T cells are potent early mediators of the host response to sepsis. Shock 34(4):327–336. https://doi.org/10.1097/SHK.0b013e3181e14c2e

Article  CAS  PubMed  Google Scholar 

Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG (2010) Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research. J Pharmacol Pharmacother 1(2):94–99. https://doi.org/10.4103/0976-500x.72351

Article  PubMed  PubMed Central  Google Scholar 

Kim JH, Kim J, Chun J, Lee C, Im JP, Kim JS (2018) Role of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury. Sci Rep 8(1):3797. https://doi.org/10.1038/s41598-018-22218-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kishta OA, Goldberg P, Husain SN (2012) Gadolinium chloride attenuates sepsis-induced pulmonary apoptosis and acute lung injury. ISRN Inflamm 2012:393481. https://doi.org/10.5402/2012/393481

Article  PubMed  PubMed Central  Google Scholar 

Koh SJ, Kim JM, Kim IK, Kim N, Jung HC, Song IS, Kim JS (2011) Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice. Am J Physiol Gastrointest Liver Physiol 301(1):G9-19. https://doi.org/10.1152/ajpgi.00267.2010

Article  CAS  PubMed  Google Scholar 

Koh J, Kwak Y, Kim J, Kim WH (2020) High-throughput multiplex immunohistochemical imaging of the tumor and its microenvironment. Cancer Res Treat 52(1):98–108. https://doi.org/10.4143/crt.2019.195

Article  CAS  PubMed  Google Scholar 

Kumar V (2020) Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury. Front Immunol 11:1722. https://doi.org/10.3389/fimmu.2020.01722

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee C, Chun J, Hwang SW, Kang SJ, Im JP, Kim JS (2014) Enalapril inhibits nuclear factor-κB signaling in intestinal epithelial cells and peritoneal macrophages and attenuates experimental colitis in mice. Life Sci 95(1):29–39. https://doi.org/10.1016/j.lfs.2013.11.005

Article  CAS  PubMed  Google Scholar 

Lee J, Son W, Hong J, Song Y, Yang CS, Kim YH (2021) Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis. J Control Release 336:344–353. https://doi.org/10.1016/j.jconrel.2021.06.022

Article  CAS  PubMed  Google Scholar 

Li XH, Gong X, Zhang L, Jiang R, Li HZ, Wu MJ, Wan JY (2013) Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1. Mediators Inflamm 2013:354087. https://doi.org/10.1155/2013/354087

Article  CAS  PubMed  PubMed Central 

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