Abilify Asimtufii® (aripiprazole). Prescribing information. Otsuka America Pharmaceutical, Inc., 2023.

Abilify Maintena® (aripiprazole). Prescribing information. Otsuka America Pharmaceutical, Inc., 2020.

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.

Book  Google Scholar 

American Psychiatric Association. Practice guideline for the treatment of patients with bipolar disorder. 2nd ed. Arlington, VA: American Psychiatric Association; 2010.

Google Scholar 

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2022.

Book  Google Scholar 

Bartoli F, Bachi B, Calabrese A, et al. Effect of long-acting injectable antipsychotics on emergency department visits and hospital admissions in people with bipolar disorder: a retrospective mirror-image analysis from the Northern Milan Area Cohort (NOMIAC) study. J Affect Disord. 2022;318:88–93.

Article  CAS  PubMed  Google Scholar 

Blanco C, Compton WM, Saha TD, et al. Epidemiology of DSM-5 bipolar I disorder: results from the national epidemiologic survey on alcohol and related conditions–III. J Psychiatr Res. 2017;84:310–7.

Article  PubMed  Google Scholar 

Brenner CJ, Shyn SI. Diagnosis and management of bipolar disorder in primary care. Med Clin North Am. 2014;98(5):1025–48.

Article  PubMed  Google Scholar 

Calabrese JR, Sanchez R, Jin N, et al. Efficacy and safety of aripiprazole once-monthly in the maintenance treatment of bipolar I disorder: a double-blind, placebo-controlled, 52-week randomized withdrawal study. J Clin Psychiatry. 2017;78(3):324–31.

Article  PubMed  Google Scholar 

Chakrabarty T, Torres IJ, Bond DJ, Yatham LN. Inflammatory cytokines and cognitive functioning in early-stage bipolar I disorder. J Affect Disord. 2019;245:679–85.

Article  CAS  PubMed  Google Scholar 

Chen AT, Nasrallah HA. Neuroprotective effects of the second generation antipsychotics. Schizophr Res. 2019;208:1–7.

Article  CAS  PubMed  Google Scholar 

Cirone C, Secci I, Favole I, et al. What do we know about the long-term course of early onset bipolar disorder? A review of the current evidence. Brain Sci. 2021;11(3):341.

Article  PubMed  PubMed Central  Google Scholar 

Clemente AS, Diniz BS, Nicolato R, et al. Bipolar disorder prevalence: a systematic review and meta-analysis of the literature. Braz J Psychiatry. 2015;37(2):155–61.

Article  PubMed  Google Scholar 

Cotton SM, Berk M, Jackson H, et al. Improving functional outcomes in early-stage bipolar disorder: the protocol for the REsearch into COgnitive and behavioural VERsatility trial. Early Interv Psychiatry. 2019;13(6):1470–9.

Article  PubMed  Google Scholar 

Craddock N, Sklar P. Genetics of bipolar disorder. Lancet. 2013;381(9878):1654–62.

Article  CAS  PubMed  Google Scholar 

Grewal M, Dragon J, Golub JS. Age-related disparities in the treatment of borderline/mild hearing loss in the United States. OTO Open. 2022;6(1):2473974X221083092.

Article  PubMed  PubMed Central  Google Scholar 

He L, Xie X, Xue J, et al. Association of the systemic immune-inflammation index with all-cause mortality in patients with arteriosclerotic cardiovascular disease. Front Cardiovasc Med. 2022;9:952953.

Article  CAS  PubMed  PubMed Central  Google Scholar 

He P, Ye Z, Liu M, et al. Association of handgrip strength and/or walking pace with incident chronic kidney disease: a UK biobank observational study. J Cachexia Sarcopenia Muscle. 2023;14(2):805–14.

Article  PubMed  PubMed Central  Google Scholar 

Innala L, Berglin E, Möller B, et al. Age at onset determines severity and choice of treatment in early rheumatoid arthritis: a prospective study. Arthritis Res Ther. 2014;16(2):R94.

Article  PubMed  PubMed Central  Google Scholar 

Lähteenvuo M, Paljärvi T, Tanskanen A, et al. Real-world effectiveness of pharmacological treatments for bipolar disorder: register-based national cohort study. Br J Psychiatry. 2023;223(4):456–64.

Article  PubMed  PubMed Central  Google Scholar 

Narasimhan M, Bruce TO, Masand P. Review of olanzapine in the management of bipolar disorders. Neuropsychiatr Dis Treat. 2007;3(5):579–87.

CAS  PubMed  PubMed Central  Google Scholar 

Nasrallah HA, Chen AT. Multiple neurotoxic effects of haloperidol resulting in neuronal death. Ann Clin Psychiatry. 2017;29(3):195–202.

PubMed  Google Scholar 

Patel M, Jain R, Tohen M, et al. Efficacy of cariprazine in bipolar I depression across patient characteristics: a post hoc analysis of pooled randomized, placebo-controlled studies. Int Clin Psychopharmacol. 2021;36(2):76–83.

Article  PubMed  Google Scholar 

Peters AT, West AE, Eisner L, et al. The burden of repeated mood episodes in bipolar I disorder: results from the national epidemiological survey on alcohol and related conditions. J Nerv Ment Dis. 2016;204(2):87–94.

Article  PubMed  PubMed Central  Google Scholar 

Poranen J, Koistinaho A, Tanskanen A, et al. Twenty-year medication use trends in first-episode bipolar disorder. Acta Psychiatr Scand. 2022;146(6):583–93.

Article  PubMed  PubMed Central  Google Scholar 

Quiroz JA, Yatham LN, Palumbo JM, et al. Risperidone long-acting injectable monotherapy in the maintenance treatment of bipolar I disorder. Biol Psychiatry. 2010;68(2):156–62.

Article  CAS  PubMed  Google Scholar 

Ratheesh A, Hett D, Ramain J, et al. A systematic review of interventions in the early course of bipolar disorder I or II: a report of the International Society for Bipolar Disorders Taskforce on early intervention. Int J Bipolar Disord. 2023;11(1):1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Risperdal Consta® (risperidone). Prescribing information. Janssen Pharmaceuticals, Inc., 2021.

Shi W, Su L, Wang J, et al. Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003–2018. Ann Med. 2022;54(1):1395–402.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stip E, Javaid S, Bayard-Diotte J, et al. Use of long acting antipsychotics and relationship to newly diagnosed bipolar disorder: a pragmatic longitudinal study based on a Canadian health registry. Ther Adv Psychopharmacol. 2020;10:2045125320957118.

Article  PubMed  PubMed Central  Google Scholar 

Tohen M, Goldberg JF, Hassoun Y, Sureddi S. Identifying profiles of patients with bipolar I disorder who would benefit from maintenance therapy with a long-acting injectable antipsychotic. J Clin Psychiatry. 2020;81(4):OT19046AH1.

Article  Google Scholar 

Verdolini N, Hidalgo-Mazzei D, Del Matto L, et al. Long-term treatment of bipolar disorder type I: a systematic and critical review of clinical guidelines with derived practice algorithms. Bipolar Disord. 2021;23(4):324–40.

Article  PubMed  Google Scholar 

Vieta E, Montgomery S, Sulaiman AH, et al. A randomized, double-blind, placebo-controlled trial to assess prevention of mood episodes with risperidone long-acting injectable in patients with bipolar I disorder. Eur Neuropsychopharmacol. 2012;22(11):825–35.

Article  CAS  PubMed  Google Scholar 

Vieta E, Salagre E, Grande I, et al. Early intervention in bipolar disorder. Am J Psychiatry. 2018;175(5):411–26.

Article  PubMed  Google Scholar 

Vöhringer PA, Perlis RH. Discriminating between bipolar disorder and major depressive disorder. Psychiatr Clin North Am. 2016;39(1):1–10.

Article  PubMed  Google Scholar 

Wong SCY, Ng MCM, Chan JKN, et al. Altered risk-taking behavior in early-stage bipolar disorder with a history of psychosis. Front Psychiatry. 2021;12: 763545.

Article  PubMed  PubMed Central  Google Scholar 

Yan T, Greene M, Chang E, et al. Medication adherence and discontinuation of aripiprazole once-monthly 400 mg (AOM 400) versus oral antipsychotics in patients with schizophrenia or bipolar I disorder: a real-world study using US claims data. Adv Ther. 2018;35(10):1612