TMEM106B amyloid filaments in the Biondi bodies of ependymal cells

Adams RD, Oksche A, and Haymaker W "Meninges, choroid plexuses, ependyma and their reactions. (1982) Part 2: Age-related changes and pathology." Histology and Histopathology of the Nervous System. Springfield, IL: Charles C. Thomas: 641–713.

Åslund A, Sigurdson CJ, Klingstedt T, Gratwohl S, Bolmont T, Dickstein DL et al (2009) Novel pentameric thiophene derivatives for in vitro and in vivo imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol 4:673–683

Article  PubMed  PubMed Central  Google Scholar 

Bacioglu M, Schweighauser M, Gray D, Lövestam S, Katsinelos A, Quaegebeur A et al (2024) Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems. Acta Neuropathol Commun 12:99

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bargmann W, Katritsis E (1966) Über die sogenannten Filamente und das Pigment im Plexus chorioideus des Menschen. Z Zellforsch 75:366–370

Article  CAS  PubMed  Google Scholar 

Bielschowsky M (1909) Eine Modifikation meines Silberimprägnationsverfahrens zur Darstellung der Neurofibrillen. J Psychol Neurol 12:135

Google Scholar 

Biondi G (1933) Ein neuer histologischer Befund am Epithel des Plexus chorioideus. Z ges Neurol Psychiat 144:161–165

Article  Google Scholar 

Biondi G (1934) Zur Histopathologie des menschlichen Plexus chorioideus und des Ependyms. Arch Psychiatr Nervenkrankh 101:66–728

Article  Google Scholar 

Bodian D (1936) A new method for staining nerve fibers and nerve endings in mounted paraffin sections. Anat Rec 65:89–97

Article  Google Scholar 

Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239–259

Article  CAS  PubMed  Google Scholar 

Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M et al (2022) Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell 185:1346–1355

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen VB, Arendall WB, Head JJ, Keedy DA, Immormino RM, Kaprai GI et al (2010) MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr D 66:12–21

Article  CAS  PubMed  Google Scholar 

Cottrell DA, Ince PG, Wardell TM, Turnbull DM, Johnson MA (2001) Accelerated ageing changes in the choroid plexus of a case with multiple mitochondrial DNA deletions. Neuropathol Appl Neurobiol 27:206–214

Article  CAS  PubMed  Google Scholar 

Croll TI (2018) ISOLDE: a physically realistic environment for model building into low-resolution electron density map. Acta Crystallogr D 74:519–530

Article  CAS  Google Scholar 

Del Rio Hortega P (1918) Noticia de un nuevo y fácil método para la coloración de la neuroglia y del tejido conjuntivo. Trab Lab Invest Biol Univ Madrid 15:367–378

Google Scholar 

Deng S, Gan L, Liu C, Xu T, Zhou S, Guo Y et al (2023) Roles of ependymal cells in the physiology and pathology of the central nervous system. Aging Dis 14:468–483

PubMed  PubMed Central  Google Scholar 

Divry P (1955) De la nature des formations argentophiles des plexus choroïdes. Acta Neurol Belg 55:282–283

CAS  Google Scholar 

Dohrmann GJ, Bucy PC (1970) Human choroid plexus: a light and electron microscopic study. J Neurosurg 33:506–516

Article  CAS  PubMed  Google Scholar 

Edwards GA, Wood CA, He Y, Nguyen Q, Kim PJ, Gomez-Gutierrez R et al (2024) TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy. Acta Neuropathol 147:61

Article  PubMed  Google Scholar 

Emsley P, Lohkamp B, Scott WG, Cowtan K (2010) Features and development of Coot. Acta Crystallogr D 66:486–501

Article  CAS  PubMed  PubMed Central  Google Scholar 

Eriksson L, Westermark P (1986) Intracellular neurofibrillary tangle-like aggregations. A constantly present amyloid alteration in the aging choroid plexus. Am J Pathol 125:124–129

CAS  PubMed  PubMed Central  Google Scholar 

Fan Y, Zhao Q, Xia W, Tao Y, Yu W, Chen M et al (2022) Generic amyloid formation of TMEM106B in a patient with Parkinson’s disease dementia and normal elders. Cell Res 32:585–588

Article  PubMed  PubMed Central  Google Scholar 

Feng T, Mai S, Roscoe JM, Shen RR, Ullah M, Zhang J et al (2020) Loss of TMEM106B and PRGN leads to severe lysosomal abnormalities and neurodegeneration in mice. EMBO Rep 21:e50219

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng T, Du H, Yang C, Wang Y, Hu F (2024) Loss of TMEM106B exacerbates tau pathology and neurodegeneration in PS19 mice. Acta Neuropathol 147:62

Article  CAS  PubMed  Google Scholar 

Guo H, Franken E, Deng Y, Benlekbir S, Lezcano GS, Janssen B et al (2020) Electron-event representation data enable efficient cryo-EM file storage with full preservation of spatial and temporal resolution. IUCrJ 7:860–869

Article  CAS  PubMed  PubMed Central  Google Scholar 

He S, Scheres SHW (2017) Helical reconstruction in RELION. J Struct Biol 193:163–176

Article  Google Scholar 

Hoq MR, Bharath SR, Hallinan GI, Fernandez A, Vago FS, Ozcan KA et al (2023) Cross-β helical filaments of tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia. Acta Neuropathol 145:707–710

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ikonomovic MD, Abrahamson EE, Price JC, Mathis CA, Klunk WE (2016) Positron emission tomography retention in choroid plexus: More than “off target” binding. Ann Neurol 80:307–308

Article  PubMed  PubMed Central  Google Scholar 

Ishikawa R, Yamazaki Y, Nakamori M, Takahashi T, Maruyama H (2023) Antibody recognizing residues 188–211 of TMEM106B exhibit immunohistochemical reactivity with the TMEM106B C-terminal fragment. Front Neurosci 17:1250547

Article  PubMed  PubMed Central  Google Scholar 

Jiang YX, Cao Q, Sawaya MR, Abskharon R, Ge OP, DeTure M et al (2022) Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature 605:304–309

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kelényi G (1967) Thioflavin S fluorescent and Congo red anisotropic stainings in the histologic demonstration of amyloid. Acta Neuropathol 7:336–348

Article  PubMed  Google Scholar 

Kimanius D, Dong L, Sharov G, Nakane T, Scheres SHW (2021) New tools for automated cryo-EM single-particle analysis in RELION-4.0. Biochem J 478:4169–4185

Article  CAS  PubMed  Google Scholar 

Marks JD, Ayuso VE, Carlomagno Y, Yue M, Todd TW, Hao Y et al (2024) TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Sci Transl Med 16(730):eadf9735

Article  CAS  PubMed  PubMed Central  Google Scholar 

May C, Kaye JA, Atack JR, Schapiro MB, Friedland RP, Rapoport SI (1990) Cerebrospinal fluid production is reduced in healthy aging. Neurology 40:500–503

Article  CAS  PubMed  Google Scholar 

Miklossy J, Kraftsik R, Pillevuit O, Lepori D, Genton C, Bosman FT (1998) Curly fiber and tangle-like inclusions in the ependyma and choroid plexus – a pathogenetic relationship with the cortical Alzheimer-type changes? J Neuropathol Exp Neurol 57:1202–1212

Article  CAS  PubMed  Google

留言 (0)

沒有登入
gif