Moving towards more personalized approaches in locally advanced and metastatic colorectal cancer

Yaeger, R. et al. Efficacy and safety of adagrasib plus cetuximab in patients with KRASG12C-mutated metastatic colorectal cancer. Cancer Discov. 14, 982–993 (2024).

Article  PubMed  PubMed Central  Google Scholar 

Yaeger, R. et al. Adagrasib with or without cetuximab in colorectal cancer with mutated KRAS G12C. N. Engl. J. Med. 388, 44–54 (2023).

Article  CAS  PubMed  Google Scholar 

Adam, R. et al. Liver transplantation plus chemotherapy versus chemotherapy alone in patients with permanently unresectable colorectal liver metastases (TransMet): results from a multicentre, open-label, prospective, randomised controlled trial. Lancet 404, 1107–1118 (2024).

Article  CAS  PubMed  Google Scholar 

Adam, R. et al. Safety and feasibility of chemotherapy followed by liver transplantation for patients with definitely unresectable colorectal liver metastases: insights from the TransMet randomised clinical trial. eClinicalMedicine 72, 102608 (2024).

Article  PubMed  PubMed Central  Google Scholar 

Chalabi, M. et al. Neoadjuvant immunotherapy in locally advanced mismatch repair–deficient colon cancer. N. Engl. J. Med. 390, 1949–1958 (2024).

Article  CAS  PubMed  Google Scholar 

Creasy, J. M. et al. Actual 10-year survival after hepatic resection of colorectal liver metastases: what factors preclude cure? Surgery 163, 1238–1244 (2018).

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif